pancreatic cancers
Rs488087 single nucleotide polymorphism as predictive risk factor for pancreatic cancers
... of pancreatic cancer (adenocarcinoma) was made after histochemical analysis of the resected ...after pancreatic resection (duodeno-pancreatectomy) in patients diagnosed with either adenocarcinoma (PDAC; 30 ...
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Powerful Inhibition of Experimental Human Pancreatic Cancers by Receptor Targeted Cytotoxic LH-RH analog AEZS-108
... for pancreatic carcinoma; treatment methods vary by location and economic ...advanced pancreatic cancers; latest reviews from around the world express overall disappointment with these ...of ...
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Risk of multiple pancreatic cancers in CDKN2A-p16-Leiden mutation carriers
... In order to study the effect of BMP9 in vitro and in vivo on cancer cells and tumor growth, we used a soluble chimeric protein consisting of the ALK1 extracellular domain (ECD) fused to [r] ...
13
CCDC88A, a prognostic factor for human pancreatic cancers, promotes the motility and invasiveness of pancreatic cancer cells
... In this study, we showed that CCDC88A is a significant prognostic factor whose expression levels predict the overall survival of patients with PDAC. Individual clini- copathological factors were not significantly ...
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CETN1 is a cancer testis antigen with expression in prostate and pancreatic cancers
... pancreatic xenografts. Unexpectedly however, CETN1 expression was virtually absent in various cell lines until they were treated with the DNA demethylation agent 5 ’ AZA-2 ’ Deoxycytidine (AZA) but showed no ...
7
Subgroup analysis reveals molecular heterogeneity and provides potential precise treatment for pancreatic cancers
... of pancreatic cancer remains unclear. In this study, pancreatic cancer was divided into different subgroups to explore its specific molecular characteristics and potential therapeutic ...
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A case study of a collision tumor composed of cancers of the bile duct and pancreas
... collision cancers in which periampullary carcinoids and adenocarcinomas collided, the difference in the origins of the tumors was observed on CEA stain- ing ...of cancers presenting in the bile duct and the ...
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Distribution and pathological features of pancreatic, ampullary, biliary and duodenal cancers resected with pancreaticoduodenectomy
... In the large series by Winter et al. of 1,175 resected pancreatic cancers, 42% had a positive margin. Margin status has been shown to relate to survival outcomes. Yeo et al. showed in their series of 201 ...
7
Tumor-targeting Salmonella typhimurium A1-R arrests growth of breast-cancer brain metastasis
... and pancreatic cancers [11-13], including pancreatic cancer stem cells [14] and pancreatic cancer patient- derived orthotopic xenograft [PDOX] models [15], as well as sarcoma [12, 18] and ...
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Clinical significance of pancreatic circulating tumor cells using combined negative enrichment and immunostaining-fluorescence in situ hybridization
... of pancreatic cancers and centrosome abnormalities of chromosome 8 ap- peared in all of 16 analyzed pancreatic cell lines using FISH, thus, the variation of chromosome numbers could be reflected by ...
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Original Article Gene Expression Profiles Associated with Advanced Pancreatic Cancer
... of pancreatic cancer to advanced ...resected pancreatic cancers (stages pT2/T3), late stage unresectable cancers (stage pT4) and matched metastases to a variety of organ ...primary ...
12
Germline mutations in Japanese familial pancreatic cancer patients
... Familial Pancreatic Cancer Registry (JFPCR) was established in 2015 [29], 20 years after the American registry (the National Familial Pancreatic Tumor Registry, NFPTR) ...
9
<p>Significance of CXCL12/CXCR4 Ligand/Receptor Axis in Various Aspects of Acute Myeloid Leukemia</p>
... interactions. 7,16 To perform its activities, CXCL12 attaches to two namely receptors, CXCR4 and CXCR7 and further transduces on the mTOR pathway in pancreatic and gastric cancers, T cell leukemia, and the ...
11
Recent advances in the ARID family: focusing on roles in human cancer
... Like ARID4A, ARID4B has been found to be an mSIN3- HDAC complex-associated protein. The ARID4B gene is also known as breast cancer-associated antigen 1 (BRCAA1) and is highly expressed in human breast, lung, colon, ...
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B7x—from bench to bedside
... various cancers and in prostate cancer its expression is corelated with poorer ...various cancers promotes B7x expression and tumor immune ...in cancers and increasing B7x expression with fusion ...
5
Identification of potential biomarkers for diagnosis of pancreatic and biliary tract cancers by sequencing of serum microRNAs
... these cancers from control subjects, regardless of stage, can be ...distinguish cancers, we believe that ap- plication of our model without adjusting for ...
11
<p>Research progress of cystatin SN in cancer</p>
... cancer, pancreatic cancer, and colorectal cancer, high cystatin SN expression in cancer tissues but low cystatin SN expression in peritumoral normal tissues was ...cystatin, cancers, signaling pathway, ...
9
Sonidegib: mechanism of action, pharmacology, and clinical utility for advanced basal cell carcinomas
... Sonidegib may have a strong role as an adjunct therapy in the treatment of other cancers. With its observed potentiating effects in multiple cancer types, the approval of additional clinical applications for ...
9
Therapeutic potential of hedgehog signaling pathway agonist
... human cancers are presented with activated Hh signaling, including brain tumors, melanomas, leukemias, lymphomas, gastrointestinal, kidney, bladder, pancreatic, liver, prostate, lung, ovarian and breast ...
7
Higher Prevalence of Prostate Cancer among Veterans with Type 2 Diabetes
... for cancers in their joint position ...and cancers such as lung cancer and lymphomas; and reduced risk of prostate cancer among sub- jects with type 2 ...some cancers such as liver, pancreas, colon ...
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