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Pancreatic Ductal

Neurotensin receptors in pancreatic ductal carcinomas

Neurotensin receptors in pancreatic ductal carcinomas

... Pancreatic ductal carcinoma samples were collected at the Department of General, Visceral and Transplantation Surgery, University Hospital Heidelberg, Heidelberg, Germany, and at the Institute of Pathology, ...

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MAPLE PD trial (Mesenteric Approach vs  Conventional Approach for Pancreatic Cancer during Pancreaticoduodenectomy): study protocol for a multicenter randomized controlled trial of 354 patients with pancreatic ductal adenocarcinoma

MAPLE PD trial (Mesenteric Approach vs Conventional Approach for Pancreatic Cancer during Pancreaticoduodenectomy): study protocol for a multicenter randomized controlled trial of 354 patients with pancreatic ductal adenocarcinoma

... with pancreatic ductal adenocarcinoma scheduled to undergo pancreaticoduodenectomy are randomized before operation to either a conventional approach (arm A) or a mesenteric approach (arm ...

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The Changes of Autophagy in Pancreatic Stem
Cells for Patients with Pancreatic Ductal Cancer

The Changes of Autophagy in Pancreatic Stem Cells for Patients with Pancreatic Ductal Cancer

... Pancreatic ductal adenocarcinoma (PDAC) is the fourth leading cause of cancer death in United States and is ranked as the 10th~11th cancer frequently associated the cancer mortality in ...

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Pancreatic ductal cells in development, regeneration, and neoplasia

Pancreatic ductal cells in development, regeneration, and neoplasia

... The pancreas is a complex organ comprised of three critical cell lineages: islet (endocrine), acinar, and ductal. This review will focus upon recent insights and advances in the biology of pancreatic ...

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Angiogenesis in pancreatic ductal adenocarcinoma: A controversial issue

Angiogenesis in pancreatic ductal adenocarcinoma: A controversial issue

... Pancreatic ductal adenocarcinoma (PDAC) occurs in the majority of cases with early loco-regional spread and distant metastases at diagnosis, leading to dismal prognosis with a 5-year overall survival rate ...

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Rac1b negatively regulates TGF-β1-induced cell motility in pancreatic ductal epithelial cells by suppressing Smad signalling

Rac1b negatively regulates TGF-β1-induced cell motility in pancreatic ductal epithelial cells by suppressing Smad signalling

... of pancreatic ductal adenocarcinoma (PDAC) by enhancing epithelial-mesenchymal transition, cell migration/invasion, and metastasis, in part by cooperating with the small GTPase ...in pancreatic ...

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Interventional Nanotheranostics of Pancreatic Ductal Adenocarcinoma

Interventional Nanotheranostics of Pancreatic Ductal Adenocarcinoma

... Pancreatic ductal adenocarcinoma (PDAC) accounts for over 90% of all pancreatic cancer. Nanoparticles (NPs) offer new opportunities for image-guided therapy owing to the unique physicochemical ...

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Stromal fibronectin expression in patients with resected pancreatic ductal adenocarcinoma

Stromal fibronectin expression in patients with resected pancreatic ductal adenocarcinoma

... Pancreatic ductal adenocarcinoma (PDAC) is the third leading cause of cancer death, characterized by frequent metastases and profound chemoresistance ...of pancreatic cancer com- bined is 6 months, ...

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PKM2 is not required for pancreatic ductal adenocarcinoma

PKM2 is not required for pancreatic ductal adenocarcinoma

... in pancreatic can- cer have also been ...in pancreatic cancer cell lines ...of pancreatic cancer patients [20, 24, 27, ...in pancreatic cancer [30, ...

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T Cell Immunosurveillance in Pancreatic Ductal Adenocarcinoma

T Cell Immunosurveillance in Pancreatic Ductal Adenocarcinoma

... as pancreatic intraepithelial neoplasia (PanIN) (Hidalgo, ...Accordingly, pancreatic cancer in the mouse model is driven by the targeted expression of activating Kras G12D and dominant negative Trp53 R172H ...

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Targeting dendritic cells in pancreatic ductal adenocarcinoma

Targeting dendritic cells in pancreatic ductal adenocarcinoma

... In addition to the use of peptides as pulsation substance, lysed tumor cells can be used. Tumor lysate can be gen- erated by multiple freeze–thaw cycles or UV-irradiation of tumor cells. The potential benefits include a ...

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Prognostic value of microRNA 21 in pancreatic ductal adenocarcinoma: a meta analysis

Prognostic value of microRNA 21 in pancreatic ductal adenocarcinoma: a meta analysis

... should be convenient, sensitive, and credible. The majority of pooled studies detected the miR-21 expression in the tissue with qRT-PCR method. Elevated expression of miR- 21 in the serum sample also predicted poor ...

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Adjuvant chemotherapy after surgery for pancreatic ductal adenocarcinoma: retrospective real life data

Adjuvant chemotherapy after surgery for pancreatic ductal adenocarcinoma: retrospective real life data

... Data was obtained from in-house medical records and from the database of the comprehensive cancer center, as well as follow-up reports from oncologists and general practitioners. Examined parameters included patients’ ...

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Pancreatic cancer accompanied by a moderate-sized pseudocyst with extrapancreatic growth

Pancreatic cancer accompanied by a moderate-sized pseudocyst with extrapancreatic growth

... moderate-sized pancreatic cyst on the pancreatic body with extrapancreatic ...the pancreatic body was an extrapancreatic growth with poor enhancement, which was approximately 52 × 32 × 23 mm in ...

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The Ubiquitin-Proteasome Pathway Mediates Gelsolin Protein Downregulation in Pancreatic Cancer

The Ubiquitin-Proteasome Pathway Mediates Gelsolin Protein Downregulation in Pancreatic Cancer

... Antibody microarrays (BD Clontech 380, Cat. K1847-1, Lot. 2070683) were obtained from BD Biosciences Clontech (Palo Alto, CA, USA), and sample prepa- ration and processing procedures were performed as described in the ...

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Case Report Pancreatic intraglandular metastasis of the ductal adenocarcinoma: cases of 2 and literature review

Case Report Pancreatic intraglandular metastasis of the ductal adenocarcinoma: cases of 2 and literature review

... the pancreatic parenchyma and separated from the dominant; 2) a histo- logical appearance identical to that of the pri- mary tumor; 3) differentiated to the same degree as or less than the primary tumor; and 4) ...

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Research Progress of HOXA13/HOTTIP Gene and Digestive Tract Cancer

Research Progress of HOXA13/HOTTIP Gene and Digestive Tract Cancer

... in pancreatic ductal carcinoma than in normal pancreatic tissue; immunohistochemical results suggest that high expression of HOXA13 and pancreatic ductal adenocarcinoma with lymph node ...

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Predictors of Malignancy in Chronic Pancreatitis.

Predictors of Malignancy in Chronic Pancreatitis.

... and pancreatic carcinoma may present with the same ...differentiate pancreatic cancer from chronic pancreatitis, and, used in combination, they can accomplish these goals with considerable ...or ...

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Role of SATB2 in human pancreatic cancer: Implications in transformation and a promising biomarker

Role of SATB2 in human pancreatic cancer: Implications in transformation and a promising biomarker

... normal pancreatic ductal epithelial (HPNE) cells were purchased from American Type Culture Collection (ATCC), Manassas, ...mice. Pancreatic cancer cell lines were grown in Dulbecco’s Modified Eagle’s ...

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1 Introducing the "K- ShapedS ign", AN ew Finding on2 CT to DetectE arly- StageP ancreatic Cancer3

1 Introducing the "K- ShapedS ign", AN ew Finding on2 CT to DetectE arly- StageP ancreatic Cancer3

... between the extent of fatty infiltration in the pancreas and pancreatic ductal adenocarcinoma. 5) identified 3 cases of pancreatic carcinoma in situ and reported [r] ...

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