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Paracetamol induced liver toxicity

Evaluation of Hepatoprotective Activity of Zanthoxylum armatum on Paracetamol-induced Liver Toxicity in Rats

Evaluation of Hepatoprotective Activity of Zanthoxylum armatum on Paracetamol-induced Liver Toxicity in Rats

... for toxicity in rats at a dose of 2000 mg/kg, which revealed no mortality or any behavioural ...the paracetamol-induced liver toxicity model in rats at different concentrations (125, ...

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PHYTOCHEMICAL SCREENING AND HEPATOPROTECTIVE EFFICACY OF LEAVES EXTRACTS OF ANNONA SQUAMOSA AGAINST PARACETAMOL INDUCED LIVER TOXICITY IN RATS

PHYTOCHEMICAL SCREENING AND HEPATOPROTECTIVE EFFICACY OF LEAVES EXTRACTS OF ANNONA SQUAMOSA AGAINST PARACETAMOL INDUCED LIVER TOXICITY IN RATS

... tetrachloride, paracetamol or acetaminophen , ethanol, thioacetamide, rifampicin, isoniazid and pyrazinamide induced liver ...against paracetamol-induced liver toxicity ...

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Design and evaluation of herbal hepatoprotective formulation against paracetamol induced liver toxicity

Design and evaluation of herbal hepatoprotective formulation against paracetamol induced liver toxicity

... In liver injury, transport function of the hepatocytes gets disturbed, resulting in the leakage of plasma membrane and thereby causing an increased enzyme level in ...in liver. ALP is excreted by ...

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Hepatoprotective effect of Phytosome Curcumin against paracetamol-induced liver toxicity in mice

Hepatoprotective effect of Phytosome Curcumin against paracetamol-induced liver toxicity in mice

... on paracetamol induced liver damage in ...and toxicity was induced by paracetamol (500 mg/kg) during 7 ...and liver function markers (ALT, AST), hepatic antioxidants (SOD, ...

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Hepatoprotective effect of polyherbal preparation against paracetamol-induced liver toxicity in rats

Hepatoprotective effect of polyherbal preparation against paracetamol-induced liver toxicity in rats

... from liver damage which plays a pivotal role in amendable various physiological processes in the body, such as metabolism, secretion and .... Paracetamol promote development of free radicals and subsequent ...

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Protective and Therapeutic Effects of Cranberry extract against Paracetamol-induced Liver toxicity

Protective and Therapeutic Effects of Cranberry extract against Paracetamol-induced Liver toxicity

... analgesic paracetamol causes a potentially fatal, hepatic centrilobular necrosis when taken in ...against paracetamol-induced hepatotoxicity in ...elevated liver enzyme markers in a dose- ...

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Hepatoprotective effect of Rhodiola imbricata rhizome against paracetamol-induced liver toxicity in rats

Hepatoprotective effect of Rhodiola imbricata rhizome against paracetamol-induced liver toxicity in rats

... the liver where they are detoxified ( Clarke and Clarke, 1977 ). Liver transaminases such as AST (aspartate transaminase) or SGOT (serum glutamic oxaloacetic transaminase), and ALT (alanine transaminase) or ...

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Hepatoprotective effect of ethanolic extract of Trichosanthes lobata on paracetamol-induced liver toxicity in rats

Hepatoprotective effect of ethanolic extract of Trichosanthes lobata on paracetamol-induced liver toxicity in rats

... experimental liver damage ...with paracetamol, as indicated by elevated levels of serum markers (Table ...from paracetamol-induced leakage of serum markers ...

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EVALUATION OF THE HEPATOPROTECTIVE EFFECT OF UVARIA AFZELII AGAINST PARACETAMOL INDUCED LIVER TOXICITY IN WISTAR RATS

EVALUATION OF THE HEPATOPROTECTIVE EFFECT OF UVARIA AFZELII AGAINST PARACETAMOL INDUCED LIVER TOXICITY IN WISTAR RATS

... of liver and gall bladder disorders, including hepatitis, cirrhosis and ...the liver against poisoning from chemicals, environmental toxins, snake bites, insect stings, mushroom poisoning and alcohol 10 ...

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Hepatoprotective Effect of Extract of Black Cincau (Mesona palustris BL) on Paracetamol- Induced Liver Toxicity in Rats

Hepatoprotective Effect of Extract of Black Cincau (Mesona palustris BL) on Paracetamol- Induced Liver Toxicity in Rats

... cure fever, headache and other pains and is readily available without prescription. When taken in at toxic doses, it becomes a potent hepatotoxin, generating fulminated hepatic and renal tubular necrosis which is lethal ...

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Hepatoprotective action of various partitions of methanol extract of Bauhinia purpurea leaves against paracetamol induced liver toxicity: involvement of the antioxidant mechanisms

Hepatoprotective action of various partitions of methanol extract of Bauhinia purpurea leaves against paracetamol induced liver toxicity: involvement of the antioxidant mechanisms

... in liver injury, with the potential for liver failure progression [30, ...preferred toxicity model for the evaluation of hepatoprotective agents ...the liver into inactive components, ...

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Paracetamol-induced liver injury modelled in Xenopus laevis embryos

Paracetamol-induced liver injury modelled in Xenopus laevis embryos

... to paracetamol, which has similar therapeutic indications to paracetamol, such as analgesic ...and paracetamol for the depletion of GSH indicates Xenopus could have a similar toxic reaction to AMAP ...

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Does cytochrome P450 liver isoenzyme induction increase the risk of liver toxicity after paracetamol overdose?

Does cytochrome P450 liver isoenzyme induction increase the risk of liver toxicity after paracetamol overdose?

... reduces paracetamol glucuronidation by ...of paracetamol have increased urinary glucuronide conjugates compared with controls, alongside either reduced or unchanged mercapturic and cysteine conjugates, ...

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HEPATOPROTECTIVE ACTIVITY OF HERBAL FORMULATION IN PARACETAMOL INDUCED TOXICITY IN ALBINO RATS

HEPATOPROTECTIVE ACTIVITY OF HERBAL FORMULATION IN PARACETAMOL INDUCED TOXICITY IN ALBINO RATS

... Hence there is a significant reduction in the synthesis of glycogen in the disease control group of the present study. The plant extract activated the synthetic machinery of the hepatic tissue thus improving the glycogen ...

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Possible Protective Effects of Agomelatine against Paracetamol Induced Toxicity in Rats

Possible Protective Effects of Agomelatine against Paracetamol Induced Toxicity in Rats

... Abstract- Paracetamol has a reasonable safety profile when consumed in therapeutic ...(3) Paracetamol 1gm/kg for 1week orally (4) Agomelatine 40mg/kg for 2weeks and Paracetamol 1gm/kg for ...1week. ...

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LIVER FUNCTION OF WISTAR RATS FED THE COMBINED ETHANOLIC LEAF EXTRACT OF ALCHORNEA CORDIFOLIA AND COSTUS AFER IN PARACETAMOL INDUCED TOXICITY

LIVER FUNCTION OF WISTAR RATS FED THE COMBINED ETHANOLIC LEAF EXTRACT OF ALCHORNEA CORDIFOLIA AND COSTUS AFER IN PARACETAMOL INDUCED TOXICITY

... INTRODUCTION Medicinal plants are of particular importance because they contain useful secondary products with high potency in the management of human ailments. it is generally assumed that the active constituents ...

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Tremendous effect of Salsola tetrandra and Salsola baryosma on a liver toxicity using paracetamol overdose

Tremendous effect of Salsola tetrandra and Salsola baryosma on a liver toxicity using paracetamol overdose

... against paracetamol-instigated intense hepatorenal toxicity in ...rats. Toxicity was stimulated by administration of a single oral dose of paracetamol (3 g/kg body ...ameliorate liver ...

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Comparison of effects of high and low dose paracetamol treatment and toxicity on brain and liver in rats

Comparison of effects of high and low dose paracetamol treatment and toxicity on brain and liver in rats

... that paracetamol has opposite or paradoxical effects on brain ...example, paracetamol at a dose of 15 mg/kg was found to reduce brain damage and apoptosis after hypovolemia ...that paracetamol cor- ...
COMPARITIVE STUDY OF SOLANUM XANTHOCARTUM AND SILYMARINE IN PARACETAMOL INDUCED LIVER DAMAGE

COMPARITIVE STUDY OF SOLANUM XANTHOCARTUM AND SILYMARINE IN PARACETAMOL INDUCED LIVER DAMAGE

... positive influence of synthetic drugs in liver damage have urged researchers in this field to look for herbal drugs with better hepatoprotective action. Traditional medicines are effective in certain disease and ...

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HISTOPATHOLOGICAL AND BIOCHEMICAL EFFECTS OF PARACETAMOL INDUCED TOXICITY IN FRESHWATER FISH LABEO ROHITA

HISTOPATHOLOGICAL AND BIOCHEMICAL EFFECTS OF PARACETAMOL INDUCED TOXICITY IN FRESHWATER FISH LABEO ROHITA

... KEYWORDS: Histopathology, Biochemical, Antioxidant, liver markers, Labeo rohita. 1. INTRODUCTION Fish is very important dietary animal protein source in human nutrition. Production of aquatic species through ...

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