PCL/HA
The combinatory effect of sinusoidal electromagnetic field and VEGF promotes osteogenesis and angiogenesis of mesenchymal stem cell-laden PCL/HA implants in a rat subcritical cranial defect
... on PCL/HA scaffold compared with other groups ...rBMSC-laden PCL/HA group in each time point ...MSC-laden PCL/HA group had the greatest bone formation in contrast to other groups ...
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Fabrication and characterization of pcl/ha/ppy composite scaffold using freeze-drying technique
... of PCL, PCL/HA and PCL/HA/PPY composite ...for PCL scaffold whereas for PCL/HA were between ...91.6μm. PCL/HA/PPY had pore sizes ranging from 50μm to ...
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Fabrication and characterization of chitosan coated and uncoated pcl/ha/ppy composite scaffoldsusing freeze drying technique
... measurement is the measurement technique used to determine the surface wettability of scaffolds. Properties that affects wettability measurement, includes;(1) chemical bonding, (2) surface morphology and (3) surface ...
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Characterization and development of polycaprolactone (PCL)/montmorillonite (MMT)/hydroxapaptite (HA) nanocomposites for fused deposition modelling (FDM) process
... of PCL/MMT blends increased with the decrement of tensile strength and impact ...of HA upon PCL/ MMT composite shows a slight improvement in elastic modulus, flexural modulus and flexural strength ...
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Fuzzy VIKOR Optimization for Designing High Performance Hydroxyapatite/Polycaprolactone Scaffolds for Hard Tissue Engineering
... of PCL and PCL/HA composite ...the PCL/HA composite scaffolds have better ranking than PCL scaffolds which can confirm the nanoparticles positive and significant effect on ...
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Nanocalcium-deficient hydroxyapatite–poly (ε-caprolactone)–polyethylene glycol–poly (ε-caprolactone) composite scaffolds
... Biocompatibility and osteogenesis in vivo of the n-CDAP– PCL–PEG–PCL and n-HA–PCL–PEG–PCL composite scaffolds were evaluated using histological methods. Briefly, 12 healthy New Zealand ...
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<p>Electrospun Icariin-Loaded Core-Shell Collagen, Polycaprolactone, Hydroxyapatite Composite Scaffolds for the Repair of Rabbit Tibia Bone Defects</p>
... 57 PCL is a resorbable polymer that has a much lower rate of degradation and excellent mechanical ...58 HA is also a main natural com- ponent of bone, which had been applied in BTE for long ...electrospun ...
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Selective laser sintering fabrication of nano-hydroxyapatite/poly-ε-caprolactone scaffolds for bone tissue engineering applications
... or PCL scaffolds and cultured for 28 days in ...the PCL scaffolds in ...and PCL scaffolds were implanted in rabbit femur defects for 3, 6, and 9 ...and PCL scaffolds exhibited good ...
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Bioactivity assessment of poly(ε-caprolactone)/hydroxyapatite electrospun fibers for bone tissue engineering application
... 2.2.4. Microstructure Characterization. The morphology of the fibers was observed under SEM (Hitachi TM 3000, Japan) at an accelerating voltage of 15 kV and FESEM (Hitachi SU 8020, Japan). The fibers immersed in SBF ...
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Biocompatibility of Poly-ε-caprolactone-hydroxyapatite composite on mouse bone marrow-derived osteoblasts and endothelial cells
... of HA into PCL led to heterogeneous surface properties. Variety of HA ratio to PCL generated distinct exposure of HA particle and diverse topography, which have been evidenced by SEM ...
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Biological assessment of uncoated and hydroxyapatitecoated ferum as biodegradable scaffold for hard tissue regeneration
... with HA using dip coating, a simple and cost effective method. PCL was also used as polymeric binder to improve HA coating on the surface o f the porous ...
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Preparation and characterization of antiadhesion barrier film from hyaluronic acid-grafted electrospun poly(caprolactone) nanofibrous membranes for prevention of flexor tendon postoperative peritendinous adhesion
... of PCL and PCL-g-HA NFMs allow them to maintain their mechanical integrity during ...the PCL-g-HA NFM is expected to provide better mechanical strength and an improved ability to ...
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Preparation and in vivo pharmacokinetics of curcumin-loaded PCL-PEG-PCL triblock copolymeric nanoparticles
... In this study, biodegradable poly ( ε -Caprolactone)-poly (ethylene glycol)-poly ( ε -Caprolactone) (PCL-PEG-PCL) copolymers were synthesized. CUR-NPs were produced from the self-assembly of the copolymer, ...
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Preparation, characterization and application of star-shaped PCL/PEG micelles for the delivery of doxorubicin in the treatment of colon cancer
... the PCL blocks were conjugated together by radical polymerization, forming star-shaped MPEG-PCL (SSMPEG-PCL) ...Dox/SSMPEG- PCL on colon cancer mouse model was evaluated. Dox/SSMPEG-PCL ...
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Effect of nanofiber content on bone regeneration of silk fibroin/poly(ε-caprolactone) nano/microfibrous composite scaffolds
... In this study, SF/PCL nano/microfibrous composite scaf- fold were fabricated via hybrid electrospinning method. The SF/PCL nano/microfibrous composite scaffolds were prepared by different amounts of ...
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Study on In Vitro Degradation of Bioabsorbable Polymers Poly (hydroxybutyrate co valerate) (PHBV) and Poly (caprolactone) (PCL)
... the PCL samples mass de- creased, being the period of 90 days considered as the period in which the material mass decrease was maxi- mum, as shown in Table 1 and Figure ...
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A Novel Docetaxel Loaded Poly (ε Caprolactone)/Pluronic F68 Nanoparticle Overcoming Multidrug Resistance for Breast Cancer Treatment
... As shown by Fig. 2, the docetaxel-loaded nanoparticles (PFNP) observed by FESEM were spherical in shape, and their size was around 200 nm. The surface of nanoparticles appears rough and porous. As mentioned earlier, ...
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Nanotoxicity comparison of four amphiphilic polymeric micelles with similar hydrophilic or hydrophobic structure
... However, apart from the potential applications of the four micelles prepared from PEG-PG-PCL, PEEP-PCL, PEG-PCL and PEG-DSPE in drug delivery, especially in tumor targeting delivery, the current ...
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Electrospun chitosan-graft-poly (ε-caprolactone)/poly (ε-caprolactone) nanofibrous scaffolds for retinal tissue engineering
... or PCL scaffolds after 7 days in ...on PCL scaffolds. This could be attributed to amino groups on the CS-PCL, which impart more hydrophilic sites on CS-PCL/PCL ...to PCL/gelatin ...
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Gelatinase-stimuli strategy enhances the tumor delivery and therapeutic efficacy of docetaxel-loaded poly(ethylene glycol)-poly(ε-caprolactone) nanoparticles
... This article is focused on the advantages of PEG- Pep-PCL nanoparticles in the tumor targeting and cellular uptake. Therefore, we concentrated on the gelatinase-stimuli property and the biodistribution of ...
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