Piperacillin/Tazobactam
Historical Cohort Study of the Efficacy and Safety of Piperacillin/Tazobactam Versus Fourth Generation Cephalosporins for Empirical Treatment of Febrile Neutropenia in Patients with Hematological Malignancies
... drug piperacillin/tazobactam (PIPC/TAZ) in comparison with those of fourth-generation cephalosporins (4th Cephs) as initial empirical treatment in hematological malignancies patients with febrile ...
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Intravenous piperacillin/tazobactam plus fluoroquinolone prophylaxis prior to prostate ultrasound biopsy reduces serious infectious complications and is cost effective
... with piperacillin/tazobactam and standard fluoroquinolone administration may be especially ...iv piperacillin/tazobactam antibiotic resistance in ...
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Comparison of Four Antimicrobial Susceptibility Testing Methods To Determine the In Vitro Activities of Piperacillin and Piperacillin Tazobactam against Clinical Isolates of Enterobacteriaceae and Pseudomonas aeruginosa
... (2). Tazobactam inhibits most  -lactamases produced by Escherichia coli, Klebsiella species, Proteus mirabilis, Proteus vulgaris, Providencia stuartii, Morganella morganii, and Citro- bacter koseri but not ...
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Do piperacillin/tazobactam and other antibiotics with inhibitory activity against Clostridium difficile reduce the risk for acquisition of C difficile colonization?
... receiving piperacillin/tazobactam or other inhibitory antibiotics ...receiving piperacillin/tazobactam were less likely to be asymptomatic carriers (1/36, 3 versus 7/36, 19 and 15/69, 22 %, ...
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Extensive Gene Amplification as a Mechanism for Piperacillin Tazobactam Resistance in Escherichia coli
... To preserve and extend the utility of  -lactams, some have been used in combina- tion with  -lactmase inhibitors. For example, amoxicillin, ampicillin, and piperacillin are used in combination with the  ...
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Ertapenem versus piperacillin/tazobactam for the treatment of complicated infections: a meta analysis of randomized controlled trials
... An earlier meta-analysis performed by Falagas et al [21]had provided evidence that ertapenem was compara- ble to other recommended antimicrobial regimens (piper- acillin/tazobactam, ceftriaxone plus metronidazole ...
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Assessment of Susceptibility, Pharmacodynamics, and Therapeutic Response for Interpretation of Piperacillin Tazobactam in Vitro Activity in the Treatment of Pseudomonas aeruginosa Infection
... of piperacillin binding to serum albumin the impact is practically minimal since free drug equilibrates between the intravascular and ex- travascular free body ...with piperacillin-tazobactam are the ...
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Multicenter Evaluation of the New Etest Gradient Diffusion Method for Piperacillin Tazobactam Susceptibility Testing of Enterobacterales, Pseudomonas aeruginosa, and Acinetobacter baumannii Complex
... ABSTRACT Piperacillin-tazobactam (P/T) is a  -lactam–  -lactamase inhibitor combina- tion frequently used in the hospital setting. Etest is a gradient diffusion method that represents an alternative to ...
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Co administration of vancomycin and piperacillin tazobactam is associated with increased renal dysfunction in adult and pediatric burn patients
... 46]. Piperacillin-tazobactam in comparison to other β -lactam antibiotics has been associated with impaired renal recovery by some study groups [48], and an additive detri- mental effect on renal function ...
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Piperacillin–tazobactam as alternative to carbapenems for ICU patients
... Several studies suggest that alternatives to carbapenems, and particulary beta‑lactam/beta‑lactamase inhibitor combinations, can be used for therapy of extended‑spectrum beta‑lactamase‑producing Enterobacteriaceae (ESBL‑ ...
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Pharmacokinetics of piperacillin/tazobactam in cancer patients with hematological malignancies and febrile neutropenia after chemotherapy
... Piperacillin doses between 8 g per day and 18 g per day were administered with tazobactam to four groups of healthy patients. Auclair et al. found that one- compartment model behavior was determined by ...
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Evaluation of the use of piperacillin/tazobactam (Tazocin<sup>®</sup>) at Hamad General Hospital, Qatar: are there unjustified prescriptions?
... Results: During this period, 610 prescriptions were ordered for 596 patients. The main indication for initiation of Tazocin was sepsis (207/610; 34%). The overall rate of appropriateness of empirical therapy was 348/610 ...
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Prevention of Clostridium difficilespore formation by sub inhibitory concentrations of tigecycline and piperacillin/tazobactam
... For this, we used a microscopic method to count vegetative cells and spores present within colonies growing on agar, as well as a classical spore recovery assay after growth and sporulat[r] ...
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<p>Derivation and Validation of a Risk Prediction Model for Vancomycin-Associated Acute Kidney Injury in Chinese Population</p>
... Risk factors of vancomycin-associated nephrotoxicity have been extensively studied. Higher vancomycin daily dosage, longer duration of therapy, and elevated plasma concentrations of vancomycin are widely known predis- ...
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Clinical and Microbiological Characteristics of Eggerthella lenta Bacteremia
... zole, piperacillin-tazobactam, ertapenem, and meropenem, 91% were susceptible to clindamycin, 74% were susceptible to moxifloxacin, and 39% were susceptible to ...
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Antimicrobial consumption in five adult intensive care units: a 33-month surveillance study
... consumption of broad-spectrum antimicrobial agents such as meropenem and piperacillin/tazobactam in mul- tiple ICUs in a tertiary care hospital. Meropenem con- sumption was higher than similar ICUs ...
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Intra abdominal infections: the role of different classifications on the selection of the best antibiotic treatment
... Methods: A retrospective cohort study including all adult patients discharged from hospital with a diagnosis of IAI between 1st of January and 31st of October, 2016. All variables potentially associated with pre-defined ...
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Clostridium septicum Empyema in an Immunocompetent Woman
... Her chest X-ray showed a right upper-lobe infiltrate with a large associated effusion (Figure 3).. She was started on piperacillin/tazobactam and azithromycin, intravenously.[r] ...
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DEVELOPMENT AND VALIDATION OF UV SPECTROPHOTOMETRIC AREA UNDER CURVE METHOD QUANTITATIVE ESTIMATION OF PIPERACILLIN
... consumed; the quantitative interaction is achieved within a time of more than 1 min (observation time). The method on initial rates (tangent method) was used to collect kinetic data (usually at 280 nm) by following the ...
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In Vitro Comparative Efficacy of Carbapenems and β-Lactam β-Lactamase Inhibitor Combinations Against Multi Drug Resistant Gram Negative Bacilli
... and piperacillin/tazobactam have been considered very promising antibiotics in the management of commonly encountered Gram-negative infections in the hospital ...settings ...
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