Plasmid-mediated β-lactamase
Extended-spectrum β-lactamase, plasmid-mediated AmpC β-lactamase, fluoroquinolone resistance, and decreased susceptibility to carbapenems in Enterobacteriaceae: fecal carriage rates and associated risk factors in the community of Northern Cyprus
... that plasmid- mediated quinolone resistance (PMQR) genes, qnr and aac(6′)-lb-cr, were detected in ESBL-producing isolates with reduced susceptibility to ...
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Quinolone Resistance (qnr) genes in Fecal Carriage of Extended Spectrum beta-Lactamases producing Enterobacteria isolated from Children in Niger
... of plasmid-mediated quinolone resistance (PMQR) genes can lead to the protection of quinolone's target by qnr (quinolone resistance) proteins, the hydrolysis of quinolone by aac(6')-Ib-cr protein, involving ...
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Bacterological Profile of Neonatal Septicemia with special emphasis on Plasmid Mediated Amp C β Lactamase Producing Gram Negative Isolates.
... with plasmid-mediated AmpC enzymes were consistently resistant to Aminopenicillins (Ampicillin or Amoxicillin), Carboxypenicillins (Carbenicillin or Ticarcillin), and Ureidopenicillins (Piperacillin) and, ...
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Outbreak of Dysentery Associated with Ceftriaxone Resistant Shigella sonnei: First Report of Plasmid Mediated CMY 2 Type AmpC β Lactamase Resistance in S sonnei
... are plasmid analysis and PFGE (9, 11, 16, 17, ...(12). Plasmid analysis has proven to be a useful typing technique (9, 11); it is inexpensive and quick to ...resistant plasmid, leading to the ...
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Evaluation of a New Etest for Detecting Metallo β Lactamases in Routine Clinical Testing
... the plasmid-mediated-enzyme producers do not appear to be accurately detected using cur- rent resistance breakpoint criteria, and therefore the emer- gence and spread of this resistance mechanism will not ...
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Multiplex PCR Study of Plasmid-Mediated AmpC Beta-Lactamase Genes in Clinical Isolates of Escherichia coli
... AmpC β-lactamases are important cephalosporinases chromosomally encoded in many of Enterobacteriaceae and a few other organisms where they mediate resistance to cephalothin, cefazolin, cefoxitin and ...of ...
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Laboratory Surveillance for Prospective Plasmid Mediated AmpC β Lactamases in the Kinki Region of Japan
...  -Lactamase assays. A cefazolin (CFZ) MIC of ⬎ 16 g/ml was used for the initial screening of isolates. Strains that met this criterion were tested using the three-dimensional (3D) test with cefoxitin (FOX) (30 ...
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Prevalence of Plasmid Mediated AmpC β Lactamases in a Chinese University Hospital from 2003 to 2005: First Report of CMY 2 Type AmpC β Lactamase Resistance in China
... Plasmid-mediated class C  -lactamases have been discov- ered most frequently in naturally AmpC-negative species, such as K. pneumoniae, K. oxytoca, Salmonella spp., and Proteus mirabilis, and also in E. ...
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Longitudinal Farm Study of Extended Spectrum β Lactamase Mediated Resistance
... promiscuous plasmid. Plasmid analysis has indi- cated that horizontal transfer of these elements is a very effi- cient mechanism involved in the spread of CTX-M-mediated resistance at this ...smaller ...
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Clonal dissemination of KPC-2 producing Klebsiella pneumoniae ST11 clone with high prevalence of oqxAB and rmtB in a tertiary hospital in China: results from a 3-year period
... Extended-spectrum β-lactamase (ESBLs), exogenously acquired 16S rRNA methyltrans- ferase (16S-RMTase) genes, and plasmid-mediated AmpC enzyme (pAmpCs) has been frequently detected among the ...
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First description of plasmid-mediated quinolone resistance determinants and β-lactamase encoding genes in non-typhoidal Salmonella isolated from humans, one companion animal and food in Romania
... Among the Salmonella Infantis isolates, one human isolate (isolate 19) and also the isolate from dog stool (isolate 20) displayed the same PFGE profile as four chicken meat isolates (namely, isolate 1, 2, 4 and 9) (Fig- ...
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Detection of Plasmid-Mediated AmpC Beta-lactamase Enzyme among Escherichia coli Isolates in Livestock, South Nigeria
... Generally, intensive application of antibiotics in livestock husbandry increases the abundance of extended-spectrum β-lactamase- producing Enterobacteriaceae in animals and in consequence in their manure ...
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Detection of Plasmid Mediated AmpC β Lactamase Genes in Clinical Isolates by Using Multiplex PCR
... of plasmid-mediated ampC -lactamases requires that any molecular technique used for identification of the gene be functional for different gram-negative organisms, including or- ganisms with chromosomal ...
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<p>Plasmid Profiling and Occurrence of β-Lactamase Enzymes in Multidrug-Resistant Uropathogenic <em>Escherichia coli</em> in Kathmandu, Nepal</p>
... of β -lactams has been well established for the production of β -lactamases, the most common mechanism of conferring β -lactams resis- tance among ...The β -lactamase enzyme production ...
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<p>Molecular Characterization of Carbapenem-Resistant <em>Serratia marcescens</em> Clinical Isolates in a Tertiary Hospital in Hangzhou, China</p>
... Plasmid-mediated carbapenem- hydrolysing β -lactamase KPC-2 in carbapenem-resistant Serratia marcescens isolates from Hangzhou, China. Emergence of Serratia marcescens, Klebsiella pneumo[r] ...
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New Biosensing Strategies Using Hyperpolarized Xenon-129 Nmr Spectroscopy
... HEK293T/17 cells were cultured in T25 flasks in DMEM supplemented with L- glutamine, 10% fetal bovine serum, 1% penicillin/streptomycin until 80% confluency. The medium was then removed and the cells were washed with ...
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<p>PAU-1, a Novel Plasmid-Encoded Ambler Class A β-Lactamase Identified in a Clinical <em>Pseudomonas aeruginosa</em> Isolate</p>
... Production of the Ambler class A extended-spectrum beta-lactamase (ESBL) is an important cause of cephalosporin resistance in Pseudomonas aeruginosa which is one of the most common pathogens that causes burn wound ...
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Key words
... The susceptibility test data showed that the ESBL-positive isolates (donors) were multiresist- ant strains, displaying resistance to most β-lactams and non-β-lactams. It should be emphasized that these ...
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MOLECULAR CHARACTERIZATION OF PSEUDOMONAS AERUGINOSA ISOLATES RECOVERED FROM HUMAN PATIENTS IN HIMACHAL PRADESH (INDIA) FOR SELECTIVE GENES: EXTENDED SPECTRUM β LACTAMASE (ESBL), AMPICILLIN CLASS C (AMPC) AND METALLO β LACTAMASE (MBL) GENES
... The β-lactamases (AmpC, ESBLs and MBLs) pose major therapeutic challenge to the clinicians 13 ...of β-lactamases of these isolates from this geographic region on phenotypic testing by phenotypic methods ...
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The prevalence of plasmid-mediated quinolone resistance and ESBL-production in <em>Enterobacteriaceae </em>isolated from urinary tract infections
... The rate of resistance to β -lactams and fluoroquinolones in Enterobacteriaceae isolated from UTIs is high. Amikacin and imipenem are the most effective antibiotics for empiri- cal therapy in our setting. The ...
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