Plasmodium chabaudi Cir2 Expression and Structural
Characterization and tissue specific expression patterns of the Plasmodium chabaudi cir multigene family
... the expression of certain cir anti- gen mRNAs correlates with the localization of the para- sites in particular internal organs, a first repertoire of transcribed cir genes was amplified from parasites using ...
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Sequestration and the infected-erythrocyte surface in plasmodium chabaudi malaria infection.
... Discussion expression truly responsible for the chronicity of malaria, (ii) are var-switches ordered, enabling the parasite to limit the number of variants seen by the host at any particular time, and (iii) is the ...
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Differential induction of malaria liver pathology in mice infected with Plasmodium chabaudi AS or Plasmodium berghei NK65
... and expression of tumour necrosis factor ...P. chabaudi AS infected mice although in the latter hepatomegaly was more ...P. chabaudi AS infected mice the antioxidant enzymes and the lipid content and ...
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Differential induction of malaria liver pathology in mice infected with Plasmodium chabaudi AS or Plasmodium berghei NK65
... lethal Plasmodium berghei strain NK65 and self-healing Plasmodium chabaudi strain AS which differ in their ability to cause hepatopathy and/or ARDS were used to investigate the lipid alterations, ...
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Gene expression of the liver of vaccination protected mice in response to early patent infections of Plasmodium chabaudi blood stage malaria
... Results: In vaccination‑induced healing infections, 23 genes were identified to be induced in the liver by > tenfold at p < 0.01. More than one‑third were genes known to be involved in erythropoiesis, such as Kel, Rhag, ...
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Plasticity in transmission strategies of the malaria parasite, Plasmodium chabaudi : environmental and genetic effects
... genotypes. Expression and morphology data demonstrate that transcription of assayed genes occurs before gametocytes reach maturity, but the precise timing and whether there is genetic variation in the timing are ...
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ICAM 1 is a key receptor mediating cytoadherence and pathology in the Plasmodium chabaudi malaria model
... the expression of ICAM-1 in the wild-type host, contributing both to weight loss and the development of ...P. chabaudi iRBC to bind to cell lines expressing different recombinant recep- tors in vitro would ...
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Transformation of the rodent malaria parasite Plasmodium chabaudi and generation of a stable fluorescent line PcGFPCON
... Conclusion Plasmodium chabaudi is reproducibly accessible for genetic transformation at an efficiency that is sufficient for genomic integration of introduced ...gene expression in P. ...
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Augmented particle trapping and attenuated inflammation in the liver by protective vaccination against Plasmodium chabaudi malaria
... The expression of SULT2A and CYP7A1 is known to respond positively and negatively to CAR activation, ...P. chabaudi infection and vaccination altered CAR functionality on day 8 ...gene expression by ...
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Plasticity and genetic variation in traits underpinning asexual replication of the rodent malaria parasite, Plasmodium chabaudi
... their ability to invade mature and immature RBCs to match the changing age structure of RBCs during infec- tion, as hosts develop and then recover from anaemia, they could maximize replication rate throughout infec- ...
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A synthetic tumor necrosis factor alpha agonist peptide enhances human polymorphonuclear leukocyte mediated killing of Plasmodium falciparum in vitro and suppresses Plasmodium chabaudi infection in mice
... receptor expression showed that CR3 (CD18/CD11b) and Fc gamma RIII were upregulated by TNF(70-80), which was consistent with the peptide's ability to enhance parasite killing by ...the expression of ...
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In Silico Structural Characterization of Plasmodium Falciparum Helicase, PfBrr2
... In silico analysis for interacting partners of PfBrr2 was done using STRING-DB and yeast two hybrid data from Plasmodb. STRING-DB results show that PfBrr2 interacts with various proteins which play important role in RNA ...
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Distinct kinetics of memory B-cell and plasma-cell responses in peripheral blood following a blood-stage Plasmodium chabaudi infection in mice.
... cells, with the greatest reduction on CD138 + B220 2 LLPC in bone marrow. Similarly, MHC class II and CXCR5 expression was lowest on these cells. Conversely, CXCR4 was upregulated on CD138 + cells compared with ...
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Functional, biochemical and structural analyses of two plasmodium membrane proteins
... the expression levels of the PfNitA_optEc ...PfNitA_optEc expression using NuPAGE ® protein electrophoresis and western blotted against the His-tag fused to the C-terminus (Figure ...best expression ...
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PfEMP1 expression is reduced on the surface of knobless Plasmodium falciparum infected erythrocytes
... major structural component of knobs, and the genes located telomeric to ...PfEMP1 expression in K – clones, with western blots and flow cytometry providing strong supporting ...
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Noncoding RNAs as emerging regulators of Plasmodium falciparum virulence gene expression
... Perspectives The discovery that eukaryotic genomes are pervasively transcribed — for example, 98% of the human genome [70], 85% of the S. cerevisiae genome [71], and 80% of the P. falciparum genome [31 ] — has ...
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Novel insights into telomere biology and virulence gene expression in plasmodium falciparum
... these structural adaptations regulate vital processes and display striking parallels even between highly divergent organisms, we still lack an overall picture of the mechanisms that regulate Plasmodium ...
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An AFLP based genetic linkage map of Plasmodium chabaudi chabaudi
... 6. Carlton JM, Hayton K, Cravo PV, Walliker D: Of mice and malaria mutants: unravelling the genetics of drug resistance using rodent malaria models. Trends Parasitol 2001, 17:236-242. 7. Gardner MJ, Hall N, Fung E, White ...
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Mosquito transmission of the rodent malaria parasite Plasmodium chabaudi
... c. chabaudi has been developed to facilitate efficient and reproducible trans- mission of distinct isolates of ...c. chabaudi to distinct strains of laboratory ...c. chabaudi permits analysis of ...
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Plasmodium chabaudi chabaudi malaria parasites can develop stable resistance to atovaquone with a mutation in the cytochrome b gene
... Background: Plasmodium falciparum, has developed resistance to many of the drugs in ...complex. Plasmodium falciparum in vitro resistance to ATQ has been associated with specific point mutations in the ...
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