Poorly Water-Soluble Drug
“Enhancement of Dissolution of Poorly Water Soluble Drug by Solid Dispersion Technique” by V.R.Tagalpallewar, India.
... the drug, in order to achieve a better dissolution rate which would further help in enhancing its oral ...of drug in formulation. Lack of chemical interaction between drug and carrier was confirmed ...
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Advanced Delivery of Poorly Water Soluble Drug Atorvastatin by Lipid Based Formulation
... poor water solubility and very low oral ...of poorly water soluble drug Atorvastatin Calcium, for enhancing its aqueous solubility and oral ...The drug release study shows that ...
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FORMULATION AND EVALUATION OF CO CRYSTALS OF POORLY WATER SOLUBLE DRUG
... of poorly water soluble drug Darunavir by cooling crystallization method using succinic acid as ...using water soluble polymer like Succinic acid can be prepared using cooling ...
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HYDROTROPIC SOLUBILIZATION TECHNIQUE TO CHALLENGE THE SOLUBILITY OF POORLY WATER SOLUBLE DRUG VALSARTAN
... basically poorly water soluble drug and its aqueous solubility is reported to be less than 1 mg/ml (about ...freely soluble in alcohols like methanol, ...This drug is rapidly ...
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Formulation development of topical solutions of poorly water-soluble drug indomethacin employing novel application of mixed solvency concept and their evaluation
... of poorly water-soluble drug indomethacin (as a model ...in water, combination of solubilizers as mixed solvent systems was used to decrease the overall concentration of solubilizers ...
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SOLUBILITY ENHANCEMENT OF POORLY WATER SOLUBLE DRUG USING NATURAL CARRIER
... of drug release from the ...high water retention capacity, digestible nature, binding ability, and easy ...the poorly water soluble drug atorvastatin, using solid dispersion ...
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FORMULATION AND EVALUATION OF TABLETS CONTAINING POORLY WATER SOLUBLE DRUG BY MADG METHOD
... arthritis, osteorthritis and other musculoskeletal disorder. Ibuprofen primarily absorbed from lower part of gastrointestinal tract. The main objective of the study was to develop, evaluate and optimization of tablets ...
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ENHANCEMENT OF SOLUBILITY OF POORLY WATER SOLUBLE DRUG – METRONIDAZOLE BY HYDROTROPY
... sparingly soluble in Water and in Alcohol; slightly soluble in ether and ...a poorly water-soluble ...during drug dissolution profile was found with its solid dispersions ...
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COMPEXATION OF POORLY WATER SOLUBLE DRUG WITH CYCLODEXTRIN
... of poorly soluble drug can be achieved in many ways, such as modification of drug crystal forms, addition of cosolvents, addition of surfactants, addition of cyclodextrins, ...in water. ...
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Microfluidic-controlled manufacture of liposomes for the solubilisation of a poorly water soluble drug
... 442 443 444 3.4 The effect of manufacturing methods on liposome stability and drug encapsulation over 8 weeks 445 The SHM method was previously investigated for the encapsulation of a hi[r] ...
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IN VITRO STUDY OF SELF EMULSIFYING DRUG DELIVERY SYSTEM OF POORLY WATER SOLUBLE DRUG SPIRONOLACTONE
... of poorly soluble drug was study in different oils, surfactants and co- ...of drug in 2 ml of different oils (Castor oil, Soya bean oil, Arachise oil, Capmul oil, Micloyol oil, Oleic acid and ...
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STUDY ON SELF NANO EMULSIFYING DRUG DELIVERY SYSTEM OF POORLY WATER SOLUBLE DRUG ROSUVASTATIN CALCIUM
... The aim of the present study is to improve solubility and hence bioavailability of Rosuvastatin calcium using self nanoemulsifying drug delivery system (SNEDDS). self emulsifying property of various oils was ...
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DEVELOPMENT OF DISINTEGRATION CONTROL MATRIX TABLETS OF FEBUXOSTAT
... the drug in zero order kinetics with increase in solubility and bioavailability of poorly water soluble ...for poorly water soluble drug as sustain release ...
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Journal of Applied Pharmaceutical Science
... retarded drug release but not as per USP ...the drug release as per USP specification Fig 7. High water solubility nature of Metoprolol succinate caused rapidly diffusion through hydrophilic gel ...
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FORMULATION STRATEGY FOR DISSOLUTION ENHANCEMENT OF SIMVASTATIN
... lowering drug which is known as HMG CoA ...of poorly water soluble drug, namely simvastatin, by the formation of solid dispersion and complex and also using the microwave induction ...
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Solubility and dissolution rate enhancement of efavirenz by inclusion complexation and liquid anti solvent precipitation technique
... of poorly water soluble ...the drug is added to a polar or aqueous ...of poorly water soluble drug, Efavirenz, and comparison of its aqueous solubility and ...
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SOLID DISPERSION: STRATEGY TO ENHANCE SOLUBILITY
... A poorly water soluble drug, more recently, has been defined in general terms to require more time to dissolve in the gastrointestinal fluid than it takes to be absorbed in the ...
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Preparation of Nanoparticles of Poorly Water Soluble Dronedarone by Antisolvent Addition Technique using Natural Polymer as a Stabilizer
... of poorly water soluble drug Dronedarone (DRO) by preparing nanoparticles with antisolvent precipitation ...vitro drug release and in vivo study in suitable animal ...pure drug ...
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Formulation and Evaluation of Indomethacin Solid Dispersion by using Hydrophilic Polymers
... The Poorly water-soluble drug candidates often emerge from contemporary drug discovery programs, and present formulators with considerable technical ...of poorly water ...
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Semisolid-filled Capsules of Carvedilol for Improving Dissolution Behaviour
... a poorly water- soluble drug using a combination of solid dispersion and semisolid-filled ...percent drug content was ...percent drug content and in vitro dissolution behaviour ...
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