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Population genetics, Genetic epidemiology

Approaches to estimating inbreeding coefficients in clinical isolates of Plasmodium falciparum from genomic sequence data

Approaches to estimating inbreeding coefficients in clinical isolates of Plasmodium falciparum from genomic sequence data

... the genetic epidemiology of the ...in population genetics and conservation ...within genetic epidemiol‑ ogy, and a possible framework for more complex ...

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The population genetics of parasitic nematodes of wild animals

The population genetics of parasitic nematodes of wild animals

... of genetic drift in a population, and hence the population genetic structure more ...both population genetics and epidemiology, very little is known about the ecology of ...

20

Epidemiology and genetics of rheumatoid arthritis

Epidemiology and genetics of rheumatoid arthritis

... Caribbean population of African origin living in Man- chester, UK, suggesting that the protection to this group was indeed genetically determined ...Chinese population living in an urban environment in Hong ...

8

Using genomics and population genetics to understand genetic variation in Malawi Plasmodium falciparum clinical isolates

Using genomics and population genetics to understand genetic variation in Malawi Plasmodium falciparum clinical isolates

... influenced epidemiology of malaria and options for its ...a genetic cross between a CQ sensitive and CQ resistant parasite that led to the discovery of a mutation in a putative transporter, ...

166

Phylogeography of the Lutzomyia gomezi (Diptera: Phlebotominae) on the Panama Isthmus

Phylogeography of the Lutzomyia gomezi (Diptera: Phlebotominae) on the Panama Isthmus

... the population genetics and demographic history of this vector species to assess the genetic pool, gene flow and colonization po- tential, consequently known as the population changes and ...

11

Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer.

Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer.

... for population substructure by including the eigenvectors of project-specific principal components as covariates in the model (nine for OncoArray, five for COGS, two for UK GWAS, and two for the US, BWH and POL ...

51

Diversity In Precision Medicine And Pharmacogenetics: Methodological And Conceptual Considerations For Broadening Participation

<p>Diversity In Precision Medicine And Pharmacogenetics: Methodological And Conceptual Considerations For Broadening Participation</p>

... Precision medicine is the translation of basic research on human variation at the individual and population level to increase the accuracy and precision of disease preven- tion, diagnosis, and treatment. However, ...

15

SMARTPOP: Inferring the impact of social dynamics on genetic diversity through high speed simulations

SMARTPOP: Inferring the impact of social dynamics on genetic diversity through high speed simulations

... modern population genetics, makes the strict assumption of random mating (a nec- essary condition of ...sex-specific genetic loci or mating ...

6

1-s2.0-S0168952518301264-main.pdf

1-s2.0-S0168952518301264-main.pdf

... obtained, genetic mapping is utilized to calculate the likelihood of every position in the genome being associated with the analyzed phenotype, and regions with the highest logarithm of the odds (LOD) score are ...

13

The Role of Population Genetics for Ethiopian Farm Animal Genetic Resources Conservation

The Role of Population Genetics for Ethiopian Farm Animal Genetic Resources Conservation

... livestock population, Ethiopia stands first in Africa and 10 th in the ...animal population of the country is estimated to be ...increased population size doesn’t necessarily show the state of the ...

7

PubMedCentral-PMC4780701.pdf

PubMedCentral-PMC4780701.pdf

... of population- based prospective genome-wide association studies we have identified QKI as a potential locus for incident myocardial infarc- ...of genetic variants in risk estimation for cardiovascular ...

16

Genetic Literacy and Competency

Genetic Literacy and Competency

... with genetics professionals to further eval- uate these variants and explain them to patients and their ...molecular genetic testing is likewise increasing rapidly; the list of single- gene disorders ...

9

AN EXTENSION OF A MODEL FOR THE EVOLUTION OF MULTIGENE FAMILIES BY UNEQUAL CROSSING OVER

AN EXTENSION OF A MODEL FOR THE EVOLUTION OF MULTIGENE FAMILIES BY UNEQUAL CROSSING OVER

... In my previous papers, I formulated a population genetics model and made a theoretical analysis of the nature of genetic variation in the gene family assuming mutation, unequal [r] ...

17

A Molecular Epidemiological and Genetic Diversity Study of Tuberculosis in Ibadan, Nnewi and Abuja, Nigeria

A Molecular Epidemiological and Genetic Diversity Study of Tuberculosis in Ibadan, Nnewi and Abuja, Nigeria

... global population structure is made up of 4 main clusters: one from the Cameroon clade (CAM), two from the Mycobacterium africanum West African 1, and one from other ‘‘modern’’ clinical isolates (Figure ...

11

Aedes aegypti in the Black Sea: recent introduction or ancient remnant?

Aedes aegypti in the Black Sea: recent introduction or ancient remnant?

... Sea population is a recent invasion [occur- ring in 2001 (first record in Sochi area) or shortly before] it should have close genetic affinities with some other population(s) in the reference panel, ...

13

A new sociological imperative: towards engaging with preimplantation genetic diagnosis

A new sociological imperative: towards engaging with preimplantation genetic diagnosis

... human genetics discourse in that both media and initial scholarly engagement have been characterised by mostly negative perspectives such as those expressed in the ‘designer baby’ and ‘slippery slope’ ...human ...

10

Molecular Population Genetics

Molecular Population Genetics

... of genetic diversity in a wide range of species (Nevo et ...measure genetic vari- ation, Lewontin (1991) assesses this initial stage in the analysis of genetic diversity not only as a milestone of ...

33

ddx062.pdf

ddx062.pdf

... In addition to examining studies with similar ancestry, com- bining results across ancestries provides opportunities to increase power to detect novel loci. For variant associations shared across ancestry groups, the ...

15

Fine scale population genetic structure of arctic foxes (Vulpes lagopus) in the High Arctic

Fine scale population genetic structure of arctic foxes (Vulpes lagopus) in the High Arctic

... fine-scale genetic structure using a global spatial autocorrelation technique (Mantel corre- lograms) [20, 21] implemented in the software GenAlEx ...the genetic diversity based on allele frequencies ...

6

POPULATION GENETICS OF DROSOPHILA AMYLASE. V. GENETIC BACKGROUND AND SELECTION ON DIFFERENT CARBOHYDRATES

POPULATION GENETICS OF DROSOPHILA AMYLASE. V. GENETIC BACKGROUND AND SELECTION ON DIFFERENT CARBOHYDRATES

... Frequency changes in amylase allozymes and patterns of tissue-specific expres- sion of amylase have been monitored in laboratory populations of Drosophila pseudoobscura mainta[r] ...

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