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Post-kala-azar dermal leishmaniasis

The immunology of post kala azar dermal leishmaniasis (PKDL)

The immunology of post kala azar dermal leishmaniasis (PKDL)

... Post-kala-azar dermal leishmaniasis (PKDL) is a common complication of visceral leishmaniasis (VL) caused by Leishmania donovani ...visceral leishmaniasis (VL), ...

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Leishmania Promastigote Membrane Antigen Based Enzyme Linked Immunosorbent Assay and Immunoblotting for Differential Diagnosis of Indian Post Kala Azar Dermal Leishmaniasis

Leishmania Promastigote Membrane Antigen Based Enzyme Linked Immunosorbent Assay and Immunoblotting for Differential Diagnosis of Indian Post Kala Azar Dermal Leishmaniasis

... of post-kala-azar dermal leishmaniasis (PKDL), caused by Leishmania donovani, is difficult, as the dermal lesions are of several types and resemble those caused by other skin ...

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Post kala azar dermal leishmaniasis and leprosy: case report and literature review

Post kala azar dermal leishmaniasis and leprosy: case report and literature review

... of post-kala-azar dermal leishmaniasis was established because at this time there was no hepatosplenomegaly and the bone marrow did not show Leishmania parasites thus excluding ...

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Insights into the possible role of IFNG and IFNGR1 in Kala azar and Post Kala azar Dermal Leishmaniasis in Sudanese patients

Insights into the possible role of IFNG and IFNGR1 in Kala azar and Post Kala azar Dermal Leishmaniasis in Sudanese patients

... Post Kala-azar Dermal Leishmaniasis (PKDL) is a compli- cation of treatment for patients with visceral leishmaniasis (VL) caused by Leishmania donovani and results in the ...

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Report of the Post Kala Azar Dermal Leishmaniasis (PKDL) consortium meeting, New Delhi, India, 27–29 June 2012

Report of the Post Kala Azar Dermal Leishmaniasis (PKDL) consortium meeting, New Delhi, India, 27–29 June 2012

... Cutaneous leishmaniasis; CpG: Cytosine phosphate Guanine; DAT: Direct agglutination test; DFID: Department for international development; DNDi: Drugs for neglected diseases initiative; ELISA: Enzyme- linked ...

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Identification of Clinical Immunological Determinants in Asymptomatic VL and Post Kala-azar Dermal Leishmaniasis  Patients

Identification of Clinical Immunological Determinants in Asymptomatic VL and Post Kala-azar Dermal Leishmaniasis Patients

... isceral leishmaniasis (VL) is commonly known as kala-azar in Bihar State, ...visceral leishmaniasis is usually fatal ...and post-kala-azar dermal ...

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Misdiagnosis and Mistreatment of Post-Kala-Azar Dermal Leishmaniasis

Misdiagnosis and Mistreatment of Post-Kala-Azar Dermal Leishmaniasis

... Post-kala-azar dermal leishmaniasis (PKDL) is a known complication of visceral leishmaniasis (VL) caused by L. donovani. It is rare in VL caused by L. infantum and L. chagasi ...

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Challenges for management of post kala-azar dermal leishmaniasis and future directions

Challenges for management of post kala-azar dermal leishmaniasis and future directions

... Abstract: Post kala-azar dermal leishmaniasis (PKDL) is a skin complication resulting from infection with Leishmania donovani (LD) ...visceral leishmaniasis (VL) caused by ...

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Immunoglobulin G subclass-specific antileishmanial antibody responses in Indian kala-azar and post-kala-azar dermal leishmaniasis.

Immunoglobulin G subclass-specific antileishmanial antibody responses in Indian kala-azar and post-kala-azar dermal leishmaniasis.

... visceral leishmaniasis patients, although in the present study antileishmanial antibodies of the IgG2 subclass could be demonstrated in a majority of KA ...

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Development of a Species Specific PCR Assay for Detection of Leishmania donovani in Clinical Samples from Patients with Kala Azar and Post Kala Azar Dermal Leishmaniasis

Development of a Species Specific PCR Assay for Detection of Leishmania donovani in Clinical Samples from Patients with Kala Azar and Post Kala Azar Dermal Leishmaniasis

... A clinical study was undertaken with Indian patients with KA and PKDL using PCR based on LdI primers. The PCR assay was evaluated with clinical samples from patients with KA and PKDL along with samples from suitable ...

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Imported cutaneous leishmaniasis: molecular investigation unveils Leishmania major in Bangladesh

Imported cutaneous leishmaniasis: molecular investigation unveils Leishmania major in Bangladesh

... of leishmaniasis in Bangladesh are visceral leishmaniasis and post-kala-azar dermal leishmaniasis, which are caused by Leishmania ...cutaneous leishmaniasis (CL) is ...

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Nocturnal activities and host preferences of Phlebotomus orientalis in extra domestic habitats of Kafta Humera lowlands, Kala azar endemic, Northwest Ethiopia

Nocturnal activities and host preferences of Phlebotomus orientalis in extra domestic habitats of Kafta Humera lowlands, Kala azar endemic, Northwest Ethiopia

... million kala-azar (Visceral Leishmaniasis; VL) cases in the world, 90% occur in Bangladish, India, Nepal, Sudan, Ethiopia and Brazil ...Ethiopia, kala-azar is transmitted by ...with ...

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Using focused pharmacovigilance for ensuring patient safety against antileishmanial drugs in Bangladesh’s National Kala-azar Elimination Programme

Using focused pharmacovigilance for ensuring patient safety against antileishmanial drugs in Bangladesh’s National Kala-azar Elimination Programme

... The VL elimination initiative in the ISC started in 2005 when the reported number of cases were about 10 000, 40 000 and 3000 respectively in Bangladesh, India and Nepal [4]. By 2016, a dramatic reduction of the VL ...

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Primary Hepatic Angiosarcoma in an Adolescent: Letter To Editor

Primary Hepatic Angiosarcoma in an Adolescent: Letter To Editor

... Introduction: Post Kala-azar dermal leishmaniasis is a complication of visceral leishmaniasis characterised by multiple hypopigmented, macular, maculopapular or nodular rash on ...

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Predicting Kala-Azar Disease Manifestations in Asymptomatic Patients with Latent Leishmania donovani Infection by Detection of Antibody against Recombinant K39 Antigen

Predicting Kala-Azar Disease Manifestations in Asymptomatic Patients with Latent Leishmania donovani Infection by Detection of Antibody against Recombinant K39 Antigen

... visceral leishmaniasis is suspected in only a fraction of infected persons, as the majority of these may not have clinical manifestations and remain ...visceral leishmaniasis and ...

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Laboratory confirmed miltefosine resistant cases of visceral leishmaniasis from India

Laboratory confirmed miltefosine resistant cases of visceral leishmaniasis from India

... Drug susceptibility in Leishmania isolates following miltefosine treatment in cases of visceral leishmaniasis and post kala-azar dermal leishmaniasis.. PLoS Negl Trop Dis.[r] ...

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A Comparative Study of Serum, Urine and Saliva Using rk39 Strip for the Diagnosis of Visceral Leishmaniasis

A Comparative Study of Serum, Urine and Saliva Using rk39 Strip for the Diagnosis of Visceral Leishmaniasis

... 1), post kala-azar dermal leishmaniasis (PKDL) (n= 3), past history of kala-azar (n= 2), my- cosis fungoidosis (n= 1), malaria (n= 3), and filaria (n= ...of ...

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Assessment of quality of life in patients with post kalaazar dermal leishmaniasis

Assessment of quality of life in patients with post kalaazar dermal leishmaniasis

... Visceral leishmaniasis is endemic in North-eastern states like Bihar, Jharkhand, West Bengal, Assam and Uttar Pra- desh; sporadic cases are also reported from other ...states. Post kala-azar ...

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Development of a sandwich ELISA to detect Leishmania 40S ribosomal protein S12 antigen from blood samples of visceral leishmaniasis patients

Development of a sandwich ELISA to detect Leishmania 40S ribosomal protein S12 antigen from blood samples of visceral leishmaniasis patients

... The 40S ribosomal protein S12 sandwich ELISA could detect the target antigen from Peripheral Blood Mononuclear Cell PBMC samples in 68% of VL patients and post-kala-azar dermal leishmani[r] ...

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Application of an Improved Method for the Recombinant K39 Enzyme-Linked Immunosorbent Assay To Detect Visceral Leishmaniasis Disease and Infection in Bangladesh

Application of an Improved Method for the Recombinant K39 Enzyme-Linked Immunosorbent Assay To Detect Visceral Leishmaniasis Disease and Infection in Bangladesh

... When validating a diagnostic assay for sensitivity and spec- ificity, the sample size of infected and uninfected patients needed to determine sensitivity and specificity should be cal- culated (4, 10). However, ...

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