post-translational modification(s)
Predicting the pathway involved in post-translational modification of Elongation factor P in a subset of bacterial species
... the S. cerevisiae eIF5A protein) is post-translationally modified to hypusine [N ε -(4- amino-2-hydroxybutyl)-lysine] ...a post-translational modification of eIF5A involving two ...
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Post translational modification of Parkin
... NEDD8 is another protein that shows similarity with ubi- quitin, in terms of structural homology and the way of get- ting attached to other proteins as post-translational modification [101]. Like ...
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Post-translational modification of Parkin and its research progress in cancer
... different post-translational modifications [7] which play a very important role in life ...the post-translational modification, the structure of the protein becomes more complicated, ...
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Epigenetic marking of sperm by post-translational modification of histones and protamines
... and post-translational modification identification Mascot generic format (mgfs) files were generated from MS and MS/MS raw ...N-term, S, T, Y and K, variable, ...
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Post-translational modification-regulated leukocyte adhesion and migration
... conserved modification is known to be associated with stable and long-lived microtubules, it remains enigmatic how this deeply buried acetyl group within the luminal face of the microtubule can bring about such ...
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Regulation of liver mitochondrial metabolism during hibernation by post-translational modification
... Hibernation, characterized by a seasonal reduction in metabolism and body temperature, allows animals to conserve energy when environmental conditions (e.g. temperature, food availability) are unfavourable. During ...
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Post translational modification of Ngn2 differentially affects transcription of distinct targets to regulate the balance between progenitor maintenance and differentiation
... Ngn2 post-translational modification in response to changes in the cell cycle kinase environment results in enhanced neuronal differentiation upon cell cycle ...
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Detection and analysis of disease-associated single nucleotide polymorphism influencing post-translational modification
... Post-translational modification (PTM) plays a crucial role in biological functions and corresponding disease developments. Discovering disease-associated non-synonymous SNPs (nsSNPs) altering PTM ...
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Surf the Post-translational Modification Network of p53 Regulation
... Many kinds of modifications, including phos- phorylation, acetylation and ADP-ribosylation, can change the overall charge of the amino acid residues, and in turn contribute to the electrostatic force-mediated ...
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DNA methylation and histone post-translational modification stability in post-mortem brain tissue
... The Quest 5-hmC DNA ELISA Kit (Zymo, #D5426) kits was used to measure DNA hydroxymethylation levels in the pig brain samples using the sandwich method. The manufacturer’ s suggested protocol was followed, except ...
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The interplay of post-translational modification and gene therapy
... the modification of amino acids like lysine, serine, and arginine are represented in Figure ...covalent modification of lysine via addition of one molecule of - CH 3 , two molecules of - CH 3 , and three ...
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Prediction of protein Post-Translational Modification sites: An overview
... Post-translational modi ication (PTM) refers to the covalent and enzymatic modi ication of proteins during or after protein biosynthesis. In the protein biosynthesis process, the ribosomal mRNA is ...
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POST-TRANSLATIONAL MODIFICATION OF XANTHINE DEHYDROGENASE IN A NATURAL POPULATION OF DROSOPHILA MELANOGASTER
... We are thus presented with a view of genetic variation for the xanthine dehydrogenase locus that encompasses both a high degree of structural gene heterozygosity (previously repor[r] ...
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Heterologus Protein Expression in Different Host Systems
... Advantages of this system are high expression levels, low cost, simple culture conditions, relatively rapid growth, scalable, choice of secreted or intracellular expression, efficient protein secretion and allows simple ...
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Post-translational modification of Rauscher leukemia virus precursor polyproteins encoded by the gag gene.
... JLS-V9 cells 51 chronically infected with R-MuLV and SC-1 wild mouse cell cultures 13 producing MCF murine virus 14, originally received from Janet Hartley National Cancer Institute, Bet[r] ...
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A Fast and Quantitative Method for Post-translational Modification and Variant Enabled Mapping of Peptides to Genomes.
... the modification sites but is the consequence of the differing requirement from the genomics community to only visualize single features at a ...mapping post-translational modifications onto genomic ...
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Ubiquitination of HTLV I Tax in response to DNA damage regulates nuclear complex formation and nuclear export
... the post-trans- lational modification status of Tax ...the post-translational modification status of Tax and/ or the cellular proteins with which it interacts may dictate the mechanism ...
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The pupylation pathway and its role in mycobacteria
... The post-translational modification Pup that recruits proteins for degradation by bacterial proteasomes is functionally related to the eukaryotic ubiquitin (Ub) tag without showing any sequence or ...
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Microcystin-LR (MCLR) Induces a Compensation of PP2A Activity Mediated by α4 Protein in HEK293 Cells
... Figure 2. PP2A shows opposing activity with diffuse alternations of its core enzyme protein level and post-translational modification under MCLR treatment. HEK293 cells were exposed to varying ...
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A STUDY ON THE ROLE OF DIETARY AGENT MOMORDICA CHARANTIA L ON PROTEIN GLYCATION
... spontaneous post translational modification of proteins by excess sugars causing formation of advanced glycation end products (AGEs) in diabetic individuals and responsible for diabetes ...
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