Posterior Longitudinal Ligament Ossification
Ossification of the posterior longitudinal ligament: MR evaluation
... The areas of increased signal intensity on T1-weighted images showed intermediate signal intensity on proton-density images and decreased signal intensity on T2-weighted images almost eq[r] ...
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Roles and mechanisms of leptin in osteogenic stimulation in cervical ossification of the posterior longitudinal ligament
... both positive and negative effects on bone mass [14]. Leptin positively regulates bone formation through direct actions on bone, when administrated peripherally [10, 15], and suppresses bone formation and increases ...
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Association of IL17RC and COL6A1 genetic polymorphisms with susceptibility to ossification of the thoracic posterior longitudinal ligament in Chinese patients
... The IL17RC gene encodes a single-pass type I transmem- brane protein located between the chromosomal regions 3p25.3 and 3p24.1, spanning approximately 16.55 kbp [27]. IL17RC has been implicated as an important regulator ...
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Association between single nucleotide polymorphism of IL15RA gene with susceptibility to ossification of the posterior longitudinal ligament of the spine
... IL15 receptor alpha (IL15RA) mediates IL15 function [10]. IL15 is reported to have an activity to stimulate the differentiation of osteoclast progenitors into osteoclast [11]. IL15RA is polymorphic and has been reported ...
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The H2 blocker famotidine suppresses progression of ossification of the posterior longitudinal ligament in a mouse model
... Ossi fi cation of the posterior longitudinal liga- ment (OPLL) of the spine is a common human myelopathy. 1 2 The ossi fi cation pro- gresses slowly, but leads to spinal cord com- pression. OPLL is a ...
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A new single nucleotide polymorphism affects the predisposition to thoracic ossification of the posterior longitudinal ligament
... Thoracic ossification of the posterior longitudinal ligament (T-OPLL) is one of the common factors that cause thoracic spinal stenosis, which results in intractable myelopathy and ...
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Cervical ossification of the posterior longitudinal ligament and its post surgical outcome analysis
... Fluoride intoxication, diabetes mellitus, growth-hormone imbalance, disc protrusion, recurrent minor trauma, abnormal calcium metabolism, and infection have all been suggested. A high association has been noted with ...
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Enlarged anterior cervical diskectomy and fusion in the treatment of severe localised ossification of the posterior longitudinal ligament
... The following should be considered regarding enlarged ACDF. First, the selective bone cutting proportion is essential to perform safe surgery. In our experience, the retrovertebral OPLL should be within 1⁄2 of adjacent ...
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Intraoperative evaluation using mobile computed tomography in anterior cervical decompression with floating method for massive ossification of the posterior longitudinal ligament
... and 400 mA. After we had confirmed that the region for imaging was appropriately scanned, the CT gantry was moved away from the operating table, and the CT im- ages were reviewed. In the axial images, we checked the ...
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Prognostic factors for surgical outcome in spinal cord injury associated with ossification of the posterior longitudinal ligament (OPLL)
... the posterior longitudinal ligament (OPLL) is a common cervical disease that can cause stenotic changes in the spinal canal and contribute to the development of ...
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A novel revision surgery for treatment of cervical ossification of the posterior longitudinal ligament after initial posterior surgery: preliminary clinical investigation of anterior controllable antidisplacement and fusion
... When considering revision surgery for patients who have already received posterior decompression surgery, it is impossible to again perform decompression from the posterior aspect. Anterior cervical ...
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Prevalence and distribution of ossification of the supra/interspinous ligaments in symptomatic patients with cervical ossification of the posterior longitudinal ligament of the spine: a CT based multicenter cross sectional study
... The ossification of the posterior longitudinal ligament (OPLL) and ossification of the ligamentum flavum (OLF) are characterized by the replacement of the pos- terior ...
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Genetic polymorphisms in bone morphogenetic protein receptor type IA gene predisposes individuals to ossification of the posterior longitudinal ligament of the cervical spine via the smad signaling pathway
... Several pieces of evidence have demonstrated that BMPR-IA gene is a subtype of type I BMP receptors and responsible for the initiation of osteogenic differentiation [15–17]. Previous studies using immunohistochemistry ...
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Comparison of anterior decompression and fusion versus laminoplasty in the treatment of multilevel cervical ossification of the posterior longitudinal ligament: a systematic review and meta-analysis
... and posterior surgeries, non-English studies, and ...other posterior approaches including laminectomy or laminectomy and instrumented fusion were ...
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Potential risk factors for poor outcome after anterior surgery for patients with cervical ossification of the posterior longitudinal ligament
... Advanced age, high occupying ratio of OPLL, and high residual ratio of OPLL are negative predictors for outcome of surgery in patients with OPLL. Intraoperative CSF leak- age is one of the important reasons why OPLL ...
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Investigation of ossification in the posterior longitudinal ligament using micro-focus X-ray CT scanning and histological examination
... inducing ossification in this ...continuous posterior-annular fibrosus type were observed as a projection of enthesis because both the marrow and cortex of the projection of the bone had continuity to ...
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Histological evaluation of symptomatic ossification of the anterior longitudinal ligament treated with etidronate disodium: a case report
... with ossification of the spinal column, pelvis, and attachment sites of the capsular ligament as reported by Resnick et ...anterior longitudinal liga- ment is more severely affected than the ...
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Original Article Efficacy and safety between the anterior and posterior surgery in treating the ossification of posterior cervicallongitudinal ligament (OPLL): a meta-analysis
... The ossification of the posterior cervical longitudinal ligament (OPLL) is one of the main causes of cervical spondylitis myelopathy ...and posterior surgeries have been introduced into ...
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Whole-genome sequencing reveals novel genes in ossification of the posterior longitudinal ligament of the thoracic spine in the Chinese population
... and activation of innate immunity. At present, 10 human and 12 murine TLRs have been characterized as TLR1– TLR10 in humans and TLR1–TLR9, TLR11, TLR12 and TLR13 in mice [43]. TLR1 polymorphism is associated with the ...
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Treatment for thoracic ossification of posterior longitudinal ligament with posterior circumferential decompression: complications and managements
... beak-type ossification of the posterior longitudinal liga- ment (OPLL) can be directly separated and resected, for Table 2 Peri- and post-operative complications ...
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