Pre mirnas
Herpes Simplex Virus 1 Lytic Infection Blocks MicroRNA (miRNA) Biogenesis at the Stage of Nuclear Export of Pre miRNAs
... miR-H3/H4 pre-miRNAs along with flanking sequences into the pTRIPZ vector, in which inducible gene expression is driven by a tetracycline-responsive promoter (sequences encoding pre-miR-H3 and -H4 ...
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Genome-wide identification and analysis of miRNA-related single nucleotide polymorphisms (SNPs) in rice
... primary miRNAs (pri- miRNAs) which are then processed into the precursor miRNAs (pre-miRNAs) by DCL1 in nucleus (Sun ...2012). Pre-miRNAs can be further cleaved by DCL1 ...
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Genetic variants of miRNA sequences and non–small cell lung cancer survival
... of pre-miRNAs and their surrounding ...in pre-miRNAs and their surrounding regions for all the ethnic groups (Asian, European, and African) of 400 known human ...the pre-miRNA regions ...
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Epstein-Barr Virus BART MicroRNAs Are Produced from a Large Intron prior to Splicing
... KSHV miRNAs and the structure of the mRNAs that function as the primary pre-miRNAs indicated that the KSHV miRNAs are also produced from a large intron produced by alternate splic- ing ...BART ...
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Identification of microRNAs in ecological model plant Mimulus
... Mimulus pre-miRNAs were identified after filtration and completion of the ...Mimulus miRNAs belong to twenty one families (mir 156, 157, 159, 160, 164, 172, 319, 393, 395, 397, 399, 400, 403, 417, ...
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Deciphering microRNAs and Their Associated Hairpin Precursors in a Non-Model Plant, Abelmoschus esculentus
... the miRNAs role in ...the miRNAs and their target genes, throw light to control the ...the miRNAs and their hairpin precursors, we executed NGS for miRNAs with five different ...known ...
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HIV 1 encoded candidate micro RNAs and their cellular targets
... predicted pre-miRNAs candidates in the pNL4-3 genome are ...viral pre-miRNAs from pNL4-3 (Accession Number AF 324493) [17] are ...Folded pre-miRNAs and their corresponding ...
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Changes in cellular microRNA expression induced by porcine circovirus type 2-encoded proteins
... of miRNAs [20]. Canonical miRNAs are tran- scribed by RNA polymerase II as long primary tran- scripts (pri-miRNAs), which are processed in the nucleus into ~70-nt precursor miRNAs ...
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Classification and Attribute Selection Analysis for Hexapoda miRNA
... derived pre-miRNAs attributes from secondary structure and used Chi-square, Information gain, SVM classifier for dominating attribute selection for four hexapoda ...real/pseudo miRNAs detected/missed ...
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Extracellular vesicle-packaged miRNA release after short-term exposure to particulate matter is associated with increased coagulation
... unique miRNAs and four internal controls (ath-miR159a, RNU48, RNU44 and ...0–2). MiRNAs with Crt value > 28 or AmpScore ...29. MiRNAs that were not amplified in all subjects ( n = 209) were ...
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Repertoire of bovine miRNA and miRNA-Like small regulatory RNAs expressed upon viral infection
... of pre-miRNA that results in preferential utilization of different arms of miRNA precursor ...two miRNAs (bta-mir-23b and bta-mir-27a) that demonstrated nearly equal number of sequence reads originating ...
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An in silicoanalysis of dynamic changes in microRNA expression profiles in stepwise development of nasopharyngeal carcinoma
... identify miRNAs associated with the step- wise development of NPC, miRNA microarrays were ...48 miRNAs were dif- ferentially expressed with significant change in tumor samples compared to normal samples ...
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Exosomes in Mesenchymal Stem Cells, a New Therapeutic Strategy for Cardiovascular Diseases?
... The above studies reveal that MSCs-derived ex- osomes play an essential role in MSCs-based therapy of CVDs including MI, reperfusion injury and PH. The detailed mechanisms underlying benefits of exo- somes in MSCs ...
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An integrative framework to identify cell death-related microRNAs in esophageal squamous cell carcinoma
... four miRNAs profiling data, we proposed a general framework to hunt for cell death miRNAs in a context dependent ...candidate miRNAs from hundreds of ...7 miRNAs indicated at least 3 ...
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Expression profiles of pivotal microRNAs and targets in thyroid papillary carcinoma: an analysis of The Cancer Genome Atlas
... of miRNAs and genes in the cancer signaling pathway and their use in effective tumor iden- tification, we inferred that they may be related to progressive clinical ...
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MiRNAs of peripheral blood as the biomarker of schizophrenia
... It was confirmed that about 70% of human miRNAs express in the nervous system [12] and so are variously involved in the regulation of neural structure and func- tion. For example, they play a role in the formation ...
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MicroRNAs associated with therapy of non-small cell lung cancer
... period, miRNAs involve in biological signal channels and thus influence therapeutic ...that miRNAs will be applied as powerful targets to effective therapy strategy [4, ...these miRNAs [11]. The EMT ...
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miR-10b-5p expression in Huntington’s disease brain relates to age of onset and the extent of striatal involvement
... these miRNAs had strong, positive associations to striatal and cortical H-V scores, weak positive association with disease duration and strong negative associations to onset and death ...Down-regulated ...
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MicroRNAs: powerful new regulators of heart disease and provocative therapeutic targets
... Therapeutic opportunities and challenges The obvious importance of miRNAs for cardiac function and dysfunction suggests opportunities for therapeutically exploiting the biology of miRNAs[r] ...
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miRNAs: emerging players in hematological disorders
... of miRNAs by methylation can contribute to a very promising therapeutic target of hypomethylating treatment and a useful tool in differentiating patients with poor ...
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