Predictions from in silico analysis
In silico analysis of mitochondrial proteins
... protists (Richly, Chinnery et al. 2003). The same trend was observed in all ten species: the number of mitochondrial proteins identified by all three predictors is less than 20% of that predicted by at least one ...
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In Silico Analysis of Occurrence of Tricorn Protease and Its Homologs
... Abstract: Tricorn protease is an archaeal protease acting downstream of the proteasome and together with its interacting aminopeptidases, degrades oligopeptides to free amino acids thus playing an important role in ...
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Therapy of Fabry disease with pharmacological chaperones: from in silico predictions to in vitro tests
... “in silico” method designed to predict missense mutations in the gene encoding lysosomal alpha galactosidase responsive to pharmacological ...The analysis can provide a guideline for the therapy with ...
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From Genome-Based In Silico Predictions to Ex Vivo Verification of Leprosy Diagnosis
... the analysis of human T-cell responses to novel ...cells from leprosy patients and controls in five different areas where leprosy is endemic; 246 individuals from Brazil, Nepal, Bangladesh, Pakistan, ...
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Connecting gene expression data from connectivity map and in silico target predictions for small molecule mechanism-of-action analysis
... MLP analysis is used to generate gene sets based upon their biological processes and a qualitative search is performed on the homogeneous target-based compound clusters to identify ...Our analysis show one ...
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Connecting gene expression data from connectivity map and in silico target predictions for small molecule mechanism-of-action analysis.
... data from which the link between compounds and protein target space can be ...extrapolate from knowledge to classify new and orphan ligands for potential protein targets, or off-targets, based upon the ...
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Genome analysis of a simultaneously predatory and prey independent, novel Bdellovibrio bacteriovorus from the River Tiber, supports in silico predictions of both ancient and recent lateral gene transfer from diverse bacteria
... in silico, both ancient and recent lateral gene transfer into the ...these predictions, we isolated a predatory bacterium from the River Tiber- a good potential source of LGT as it is rich in diverse ...
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Multi-Target Strategy for Pan/Foot-and-Mouth Disease Virus (FMDV) Detection: A Combination of Sequences Analysis, in Silico Predictions and Laboratory Diagnostic Evaluation
... differentiated from other vesicular ...diagnosis. From in silico approaches, different primer pairs previously reported were selected and modified to reduce the likelihood of viral escape as well as ...
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In silico guided reconstruction and analysis of ICAM 1 binding var genes from Plasmodium falciparum
... identification from these patient isolates would require alter- native methods to those employed ...allow analysis of their predicted binding ...sequence predictions alone cannot fully predict ICAM-1 ...
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In silico regulatory analysis for exploring human disease progression
... all predictions in the study are available for download from an online ...this analysis has been to incorporate a more diverse set of data including expression studies which should allow the models ...
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A Framework for assessing in silico Toxicity Predictions: Case Studies with selected Pesticides
... generated from guideline studies, are generally expressed in concentration or weight ...derived from dose-response curves (typically median values) from mg/kg to molar units, and this often improves ...
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In-Silico Analysis for cryi Gene Amplification from Bacillus thuringiensis
... amplification from B. thuringiensis. In silico analysis for designing cryI primer was carried out using some software, such as BLAST for searching cryI gene sequence, Bioedit for sequences alignment, ...
In Silico Calculations of Dipole Moment Predictions for the Bioactive Constituent Present in Vitex Negundo Plant
... Key Words: Vitex negundo plant, Dipole moment, DFT, B3LYP and HF. 1. INTRODUCTION Vitex negundo plant belongs to verbenaceae family. Leaves are aromatic, bitter, acrid, astringent, anti- inflammatory, antipyretic or ...
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Molecular Cloning and in Silico Analysis of rps7 Gene from the Lactuca sativa
... rps7 from Lactuca sativa and the other close species ...gene from Lactuca sativa plastid which has not been studied so far in ...digestion analysis and verified by sequencing. The alignment ...
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IN SILICO ADMET AND DRUG LIKENESS PREDICTIONS OF SOME SCHIFF BASES BASED 1,2,4 TRIAZOLE MOIETY
... A large number of in-silico ADMET methods have been developed [37-38]. Our main objective is to in-silico investigate our previously reported compounds [39] for their pharmacokinetic, drug-likeness, ...
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Analysis of the MAPK pathways, in silico and in vitro
... Chapter 4 Introduction Co-crystal structures do not exist for MAPKs with any of the MEK or downstream substrates. Thus, residues critical for MARK specificity have been mapped in the past using chimeric fusions and ...
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IN-SILICO ANALYSIS OF ANDROGRAPHOLIDE AGAINST CANCER
... ABSTRACT Cancer is the uncontrolled growth of abnormal cells in the body. It is the most serious disease on which extensive research is being done all over the world. Structure based drug designing offers a computational ...
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In silico analysis of the polygalacturonase inhibiting protein 1 from apple, Malus domestica
... Findings: Analysis of the MdPGIP1 nucleotide sequence revealed that the gene comprises 993 nucleotides that encode a 330 amino acid ...In silico characterization of the MdPGIP1 polypeptide revealed domains ...
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Parametric connectivity analysis in time and frequency domain from in silico and EEG data
... As regard SEM, we proved the difficulty of its approach to describe just simple situations. Even if SEM is based on linear regression as well as MVAR models, it differently assumes there is no connection with past ...
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HOMOLOGY MODELING AND ANALYSIS OF STRUCTURE PREDICTIONS OF KLF8 PROTEIN FROM HOMO SAPIENS
... Vinod Kumar Jatav*, Lovekesh Parasher, Ankit Raje and Samraddhi Tiwari Department of Biotechnology, Madhav Institute of Technology and Science, Gwalior, Madhya Pradesh, India ABSTRACT: KLF proteins are highly conserved ...
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