Prevalence of mutations
High prevalence of mutations of the p53 gene in poorly differentiated human thyroid carcinomas
... gene. Mutations were detected by single-strand conformation polymorphisms of PCR-amplified DNA, using primers bracketing the known hot spots on either exons 5, 6, 7, or ...The prevalence of mutations ...
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Prevalence of mutations in MDR3/ABCB4 gene in young patients with cholelithiasis.
... This is to certify that the dissertation “PREVALENCE OF MUTATIONS IN MDR3/ABCB4 GENE IN YOUNG PATIENTS WITH CHOLELITHIASIS”is a bonafide work of Dr.M.RADHA in partial fulfillment of the requirements for ...
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Recent uptake of intermittent preventive treatment during pregnancy with sulfadoxine–pyrimethamine is associated with increased prevalence of Pfdhfr mutations in Bobo Dioulasso, Burkina Faso
... the prevalence of infections with at least 2 Pfdhfr muta- ...greater prevalence of resist- ant ...increased prevalence of mutations [13, 14, 26, ...
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Effect of Transmission Reduction by Insecticide-Treated Bednets (ITNs) on Antimalarial Drug Resistance in Western Kenya
... the prevalence of pfcrt-76 and pfmdr1-86 mutations was high at 82% and 75%, respectively, which presumably resulted from the progression of CQ drug ...high prevalence of CQ gene mutations ...
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Trends in drug resistance codons in Plasmodium falciparum dihydrofolate reductase and dihydropteroate synthase genes in Kenyan parasites from 2008 to 2012
... the prevalence of mutation at Pfdhps codon 581 in- creased significantly from 12% in 2003 to 56% in 2007, resulting in an increase in the triple mutant Pfdhps haplo- type (A437G/K540E/A581G) from 8% to ...the ...
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PubMedCentral-PMC4963978.pdf
... that mutations occur across the entire length of the gene, making it a complex target for a molecular diagnostic to identify all causal mutations [9, ...non-synonymous mutations cause phenotypic ...
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Clinical Significance of Hepatitis B Virus (HBV) Genotypes and Precore and Core Promoter Mutations Affecting HBV e Antigen Expression in Taiwan
... the prevalence and clinical significance of hepatitis B virus (HBV) genotypes and precore and core promoter mutations in Taiwan, a cohort of 200 Taiwanese chronic hepatitis B patients was ...of ...
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Moderate prevalence of HIV-1 transmitted drug resistance mutations in southern Brazil
... The prevalence of TDRMs found in different studies varies according to the region and the population studied ...the prevalence of transmitted resistance is 1% or higher, testing for resistance before ...
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Newest data on fluoroquinolone resistance mechanism of Shigella flexneri isolates in Jiangsu Province of China
... had mutations, 298 and 152 isolates carried substitution at codon Ser80 and Ser129, ...double mutations of Ser80Ile and Ser129Pro, remarkably, these 113 isolates were also observed with mutations at ...
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Prevalence of CYP17A1 gene mutations in 17α-hydroxylase deficiency in the Chinese Han population
... 119 mutations in exons and introns have been consid- ered pathogenic or disease-causing mutations (DM) in 17α-OHD according to the ClinVar and HGMD data- bases, including missense mutations, ...
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Detection of high levels of mutations involved in anti malarial drug resistance in Plasmodium falciparum and Plasmodium vivax at a rural hospital in southern Ethiopia
... high prevalence of the pvdhfr R58 and pvdhfr N117 ...quadruple mutations were not in evidence, in the last case neither in ...multiple mutations seem to be necessary for in vivo resistance ...
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Prevalence and distribution of G6PD deficiency: implication for the use of primaquine in malaria treatment in Ethiopia
... G6PD mutations with an average frequency of ...two mutations G267+119C/T and G116A were detected with relatively low frequen- cies in this ...these mutations was associated with low G6PD enzyme ...
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Polymorphisms in chloroquine resistance associated genes in Plasmodium vivax in Ethiopia
... high prevalence of the Y976F muta- tions in pvmdr -1 in Southeast Asia where CQR prevails [19], the high prevalence of pvmdr -1 Y976F mutations identified in this study may be associated with the CQ ...
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Clonal dissemination of linezolid resistant Staphylococcus capitis with G2603T mutation in domain V of the 23S rRNA and the cfr gene at a tertiary care hospital in China
... The mutations at the central loop of the domain V re- gion on the 23S rRNA gene have been well recognized as the main mechanism mediating resistance to linezolid ...addition, mutations or deletions in genes ...
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... NOD2 mutations was significantly less frequent in CD patients with perianal ...NOD2 mutations and phenotype of the disease has been found to be week in terms of its prog- nostic power ...two ...
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Effect of trimethoprim sulphamethoxazole on the risk of malaria in HIV infected Ugandan children living in an area of widespread antifolate resistance
... mediating mutations that might ablate any protective efficacy of anti-folates? Blood sam- ples were screened for the dhfr 164L mutation, which is common in parts of South America and Asia [21], but has not shown ...
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Reproduction In Vitro of a Quasispecies from a Hepatitis C Virus-Infected Patient and Determination of Factors That Influence Selection of a Dominant Species
... non-HVR1 mutations that dis- tinguished species B from species A were candidates for adap- tive ...the mutations at I348T, E431D and/or N434T, and D610N all individually contributed to species B’s growth ...
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Prevalence of neurogenetic disorders in the North of England
... disease prevalence statistics for the North of England (see the figure for region definition) were ...point prevalence for each disorder was calculated using live affected cases and UK Office for National ...
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Sequence-based detection of mutations in cadherin 1 to determine the prevalence of germline mutations in patients with invasive lobular carcinoma of the breast
... causative mutations in this study was low, with no instances of splice site or nonsense mutations ...CDH1 mutations in patients with ILCA would not be ...
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The prevalence of transmitted HIV drug resistance among MSM in Anhui province, China
... Specific mutations included L210W, Y181C, and G190A, which confers different levels of drugs ...minor mutations which could compensate for the reduced fitness of resistant mutants, even though the minor ...
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