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primary biliary cirrhosis

PRIMARY BILIARY CIRRHOSIS

PRIMARY BILIARY CIRRHOSIS

... Primary biliary cirrhosis is worldwide in its distribution with a low prevalence of ...negative cirrhosis the diagnosis of this condition would probably ...

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Pathway-based analysis of primary biliary cirrhosis genome-wide association studies

Pathway-based analysis of primary biliary cirrhosis genome-wide association studies

... Genome-wide association studies (GWAS) have successfully identified several loci associated with primary biliary cirrhosis (PBC) risk. Pathway analysis complements conventional GWAS analysis. We ...

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Tuberculous peritonitis in a German patient with primary biliary cirrhosis: a case report

Tuberculous peritonitis in a German patient with primary biliary cirrhosis: a case report

... Case presentation: We report a case of tuberculous peritonitis in a 73-year-old female German patient. Her medical history revealed primary biliary cirrhosis (PBC) since 1992. On admission, she ...

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Deficiency of the autologous mixed lymphocyte reaction in patients with primary biliary cirrhosis

Deficiency of the autologous mixed lymphocyte reaction in patients with primary biliary cirrhosis

... with primary biliary cirrhosis (PCB) have a marked deficiency in the ability to generate an autologous mixed lymphocyte reaction (AMLR) but have a normal ability to generate an allogeneic mixed ...

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Primary biliary cirrhosis and autoimmune cholangitis are not associated with coeliac disease in Crete

Primary biliary cirrhosis and autoimmune cholangitis are not associated with coeliac disease in Crete

... Since the initial description of four patients with coeliac disease (CD) and primary biliary cirrhosis (PBC) [1], there have been several subsequent reports demonstrating an association of these two ...

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Trends in liver transplantation for primary biliary cirrhosis in the Netherlands 1988-2008

Trends in liver transplantation for primary biliary cirrhosis in the Netherlands 1988-2008

... past Primary Biliary Cirrhosis (PBC) was one of the main indications for liver transplantation (LTX), whereas nowadays, the proportion of patients receiving a transplant for PBC has decreased to ...

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Association of an overlap syndrome of autoimmune hepatitis and primary biliary cirrhosis with cytomegalovirus infection

Association of an overlap syndrome of autoimmune hepatitis and primary biliary cirrhosis with cytomegalovirus infection

... Abstract: A 63-year-old woman, who presented with severe jaundice and elevated serum conjugated bilirubin level, denied alcohol and drug use and showed no evidence of viral hepatitis. Based on clinical and laboratory ...

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Original Article Risk factors of primary biliary cirrhosis in mid-west China

Original Article Risk factors of primary biliary cirrhosis in mid-west China

... Primary biliary cirrhosis or primary biliary chol- angitis (PBC) [1, 2] is a chronic autoimmune disease with positive serum antimitochond- rial antibodies (AMA) and the immune-mediat- ...

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Towards systemic sclerosis and away from primary biliary cirrhosis: the case of PTPN22

Towards systemic sclerosis and away from primary biliary cirrhosis: the case of PTPN22

... Primary biliary cirrhosis progresses over many decades, with an unpredictable progression pattern from patient to ...to cirrhosis and liver failure within a few ...

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No Rise in Incidence but Geographical Heterogeneity in the Occurrence of Primary Biliary Cirrhosis in North East England

No Rise in Incidence but Geographical Heterogeneity in the Occurrence of Primary Biliary Cirrhosis in North East England

... In this study, we examined temporal changes in the incidence of primary biliary cirrhosis (PBC) and investigated associations between PBC incidence and sociodemographic factors and spatial ...

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Popular and unpopular infectious agents linked to primary biliary cirrhosis

Popular and unpopular infectious agents linked to primary biliary cirrhosis

... Abstract Primary biliary cirrhosis (PBC) is a progressive cholestatic liver disease characterized by the autoimmune destruction of the biliary epithelial cells of the small and medium-size ...

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Review Article Correlation between primary biliary cirrhosis and cancer risk: a meta-analysis

Review Article Correlation between primary biliary cirrhosis and cancer risk: a meta-analysis

... Received July 17, 2016; Accepted September 5, 2016; Epub November 15, 2016; Published November 30, 2016 Abstract: Primary biliary cirrhosis (PBC) is one auto-immune liver disease. Tumorigenesis is ...

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Optimal drug regimens for primary biliary cirrhosis: a systematic review and network meta-analysis

Optimal drug regimens for primary biliary cirrhosis: a systematic review and network meta-analysis

... We adhered to the PRISMA (Preferred Reporting Items for Systematic reviews and Meta-Analyses) statement for reporting systematic reviews and meta- analyses in healthcare interventions (Supplementary 4) [68]. Four ...

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Hair dyes as a risk for autoimmunity: from systemic lupus erythematosus to primary biliary cirrhosis

Hair dyes as a risk for autoimmunity: from systemic lupus erythematosus to primary biliary cirrhosis

... of primary biliary cirrhosis (PBC), a chronic cholestatic liver disease characterized by immune-mediated destruction of the small and medium sized intrahepatic bile ...

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Primary Biliary Cirrhosis in a genetically homogeneous population: Disease associations and familial occurrence rates

Primary Biliary Cirrhosis in a genetically homogeneous population: Disease associations and familial occurrence rates

... PBC: primary biliary cirrhosis; FDR: first degree relatives; AOR: adjusted odds ratio; AMA: anti-mitichondrial antibodies; PDC: pyruvate dehydrogenase complex; ...

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A case of severe osteomalacia caused by Tubulointerstitial nephritis with Fanconi syndrome in asymptomotic primary biliary cirrhosis

A case of severe osteomalacia caused by Tubulointerstitial nephritis with Fanconi syndrome in asymptomotic primary biliary cirrhosis

... Primary biliary cirrhosis (PBC) is an immune-mediated chronic cholestatic liver disease, characterized by non- suppurative destruction of interlobular bile ducts [1, ...

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Relatively high risk for hepatocellular carcinoma in patients with primary biliary cirrhosis not responding to ursodeoxycholic acid

Relatively high risk for hepatocellular carcinoma in patients with primary biliary cirrhosis not responding to ursodeoxycholic acid

... Primary biliary cirrhosis (PBC) is a chronic cholestatic liver disease, which predominantly occurs in middle-aged women. In patients with nonadvanced disease and who are treated with ursodeoxycholic ...

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DNA methylation profiling of the X chromosome reveals an aberrant demethylation on CXCR3 promoter in primary biliary cirrhosis

DNA methylation profiling of the X chromosome reveals an aberrant demethylation on CXCR3 promoter in primary biliary cirrhosis

... of primary biliary cirrhosis (PBC) remains enigmatic, there are several pieces of data supporting the thesis that a strong genetic predisposition and environmental factors interact to produce a ...

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PRIMARY BILIARY CIRRHOSIS

PRIMARY BILIARY CIRRHOSIS

... Gish RG, Gordon SC, Wright HI, Zweiban B, Podda M, Gershwin ME. Primary biliary cirrhosis in monozy- gotic and dizygotic twins: genetics, epigenetics, and environment. Gastroenterology 2004; 127: ...

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The immunogenetics of primary biliary cirrhosis: A comprehensive review

The immunogenetics of primary biliary cirrhosis: A comprehensive review

... Primary biliary cirrhosis (PBC), a classic autoimmune liver disease, is characterised by a progressive T cell predominant lymphocytic cholangitis, and a serologic pattern of reactivity in the form of ...

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