primary bronchial epithelial cells
Diesel exhaust alters the response of cultured primary bronchial epithelial cells from patients with chronic obstructive pulmonary disease (COPD) to non-typeable Haemophilus influenzae
... human cells, and demonstrated that it increases markers of the oxidative stress response, such as heme oxygenase 1 protein (HO-1, encoded by HMOX1 mRNA) in A549 cells and primary bronchial ...
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Allergen particle binding by human primary bronchial epithelial cells is modulated by surfactant protein D
... airway epithelial cells act as important immunomodulators [10] and by interac- tion with inhaled allergen, they may play an essential role in allergic asthma ...Thereby, epithelial cells can ...
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Interleukin-26 Production in Human Primary Bronchial Epithelial Cells in Response to Viral Stimulation: Modulation by Th17 cytokines
... human bronchial epithelial cells via MAP kinases ...in primary bronchial epithelial cells occurs via MAP kinases and, therefore, their simultaneous stimula- tion by ...
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Stability of gene expression by primary bronchial epithelial cells over increasing passage number
... for primary BECs have been extensively studied and have been reported elsewhere in the literature (reviewed by Gruenert et ...contaminating cells such as fibro- ...example, cells can either be grown ...
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Upregulation of MUC5AC by VEGF in human primary bronchial epithelial cells: implications for asthma
... the controls. This loss was most evident in bronchial epithelial cells. Furthermore, studies involving cultured PBECs of asthmatics showed lower caveolin-1 expression compared to that in the control ...
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Differential cytopathogenesis of respiratory syncytial virus prototypic and clinical isolates in primary pediatric bronchial epithelial cells
... continuous cells lines in vitro, which may not be representative of primary bronchial epithelial cells in- ...airway epithelial cells are the principle targets of RSV ...
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Autocrine ligands of the epithelial growth factor receptor mediate inflammatory responses to diesel exhaust particles
... These studies indicate a direct effect of DEPs on EGFR ligand expression in primary bronchial epithelial cells. EGFR ligands are involved in a number of effects that could also potentially ...
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Glutathione-S-transferase M1 regulation of diesel exhaust particle-induced pro-inflammatory mediator expression in normal human bronchial epithelial cells
... airway epithelial cells play in the pathogenesis of airway inflammation, we established the GSTM1 deficiency condition in primary bronchial epithelial cells from human volunteers ...
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Snyder_unc_0153D_19092.pdf
... CFTR-deficient cells, and increased 8-hydroxy-2-deoxyguanonsine (8OHdG) lesions were found in the mtDNA of these cells, supporting the hypothesis that CFTR deficiency can lead to mitogenomic damage even in ...
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Evidence that a primary anti-viral stimulation of the immune response by OM-85 reduces susceptibility to a secondary respiratory bacterial infection in mice
... human primary bronchial epithelial cells (BECs) originating from the lung following bronchos- copy using control and disease sampling from donors with RTI ...
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Theophylline action on primary human bronchial epithelial cells under proinflammatory stimuli and steroidal drugs: a therapeutic rationale approach
... Abstract: Theophylline is a natural compound present in tea. Because of its property to relax smooth muscle it is used in pharmacology for the treatment of airway diseases (ie, chronic obstructive pulmonary disease, ...
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Expression and regulation of immune-modulatory enzyme indoleamine 2,3-dioxygenase (IDO) by human airway epithelial cells and its effect on T cell activation
... by primary human bronchial epithelial cells was lower (~3-6 µM) than that in BEAS-2B or Calu-3 cell lines (~20-40 µM) both cell types were similarly susceptible to stimulation with TLR ligands ...
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Brushed nasal epithelial cells are a surrogate for bronchial epithelial CFTR studies
... and bronchial epithelia focused on aggregate analysis, whereas the work reported herein evaluated paired, same-subject samples ...brushed cells from the upper and lower respiratory tract that were pro- ...
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Rhinovirus Activates Interleukin-8 Expression via a Src/p110β Phosphatidylinositol 3-Kinase/Akt Pathway in Human Airway Epithelial Cells
... Human primary airway epithelial cells obtained from the tracheal trimmings of donor lungs at the time of double lung transplantation were cultured in collagen- coated plates with bronchial ...
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Cytopathogenesis of Sendai Virus in Well-Differentiated Primary Pediatric Bronchial Epithelial Cells
... tiated primary pediatric bronchial epithelial cells ...basal cells and intact tight ...nonciliated cells, not goblet cells, on the apical ...
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Fibroblast-myofibroblast transition is differentially regulated by bronchial epithelial cells from asthmatic children
... sub epithelial thickening and deposition of extra cellular matrix (ECM) as common features of airway biopsies from both adults and children ...with primary human bronchial epithelial ...
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In vitro primary cell culture as a physiologically relevant method for preclinical testing of human oncolytic adenovirus
... prostate cells via restricted replication by a prostate-specific regulatory ...nonprostate primary cells. Four primary nonprostate cell types were selected to mimic the effects of potential in ...
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Successful Readministration of Adeno-Associated Virus Vectors to the Mouse Lung Requires Transient Immunosuppression during the Initial Exposure
... the bronchial epithelium following adeno-associated virus (AAV) vector administration to the rabbit ...of primary AAV vector exposure allowed successful repeat transduction and prevented production of ...
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Expression and regulation of immune modulatory enzyme Indoleamine 2,3 dioxygenase (IDO) by human airway epithelial cells and its effect on T cell activation
... by primary human bronchial epithelial cells was lower (~3-6 µM) than that in BEAS-2B or Calu-3 cell lines (~20-40 µM) both cell types were similarly susceptible to stimulation with TLR ligands ...
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MUC1 deficiency mediates corticosteroid resistance in chronic obstructive pulmonary disease
... in bronchial epithelial growth medium (BEGM), comprising bronchial epithelial basal medium (BEBM) supplemented with bovine pituitary extract (52 μg/ml, hydrocortisone ...the epithelial ...
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