primordial follicles
From primordial germ cells to primordial follicles: a review and visual representation of early ovarian development in mice
... of primordial follicles were traditionally believed to perman- ently cease, meaning the germ cell pool size in mamma- lian females is fixed at ...ing primordial germ cells ...of primordial ...
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CDC42 controls the activation of primordial follicles by regulating PI3K signaling in mouse oocytes
... activated follicles (arrows) in control ovaries. However, numerous primordial follicles (arrowheads) and few activated follicles were observed in the Cdc42- KD ...of primordial ...
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Notch2 is required in somatic cells for breakdown of ovarian germ-cell nests and formation of primordial follicles
... Our results clearly show that Notch2 function in somatic granulosa cells is required for breakdown of germ-cell nests and formation of primordial follicles. However, the identity and cellular source of the ...
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SMAD3 directly regulates cell cycle genes to maintain arrest in granulosa cells of mouse primordial follicles
... Primordial follicles consisting of granulosa cell GC enveloped oocytes are maintained in a state of developmental arrest until activated to grow The mechanism that operates to maintain this arrested state ...
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Effects of Panax Ginseng Alcoholic Extract on Histomorphometric Changes of Ovaries in Offspring Rats from Diabetic Mothers
... of primordial, primary, secondary and graafian follicles and corpus luteum had significant reduction compared to healthy control group at 5% ...of primordial, primary, secondary and graafian ...
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A modified and tailored human follicle isolation procedure improves follicle recovery and survival
... isolated follicles and SCs was grafted for a short period of ...where follicles were isolated using the earlier protocol and grafted inside a fibrin-based matrix [21] for one ...
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Maternal exposure to polycyclic aromatic hydrocarbons diminishes murine ovarian reserve via induction of Harakiri
... Ahr is involved in in vivo–induced follicle destruction in female offspring after maternal exposure to PAHs. (A) Schematic outline of putative XRE elements, identified by a MatInspector computer algorithm within 5,000 bp ...
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Follicle stimulating hormone modulates ovarian stem cells through alternately spliced receptor variant FSH-R3
... on primordial follicles resulting in the existing paradigm that initial PF growth is gonado- tropin independent ...the primordial follicles express FSH-R3 that lacks exon 10 ...and ...
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Environmental pollutants, a possible etiology for premature ovarian insufficiency: a narrative review of animal and human data
... Premature ovarian insufficiency (POI) is a medical and biological diagnosis that affects young women, altering their quality of life and their fertility. According to the European Society of Human Reproduction and Embry- ...
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Pregnancy after drug-free in vitro activation of follicles and fresh tissue autotransplantation in primary ovarian insufficiency patient: a case report and literature review
... Based on the above, it has been suggested that in DOR and early stage of POI patients the spontaneous activa- tions of dormant primordial follicles reaching the secon- dary follicle stage. The growth of ...
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Age-related morphometrical peculiarities of Lithuanian women’s primordial ovarian follicles
... ovarian follicles are formed, they enter the prim- ordial (“resting”) stage, which persists for a period of time that varies from follicle to ...primary follicles or become atretic ...non-growing ...
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Mouse primordial germ cells produce cysts that partially fragment prior to meiosis
... The approximate correspondence between the number of cysts (4.8) at E14.5 and the number of primordial follicles (6.4) per progenitor, suggests that each cyst present at the time of meiotic entry generates ...
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Cyclic AMP in oocytes controls meiotic prophase I and primordial folliculogenesis in the perinatal mouse ovary
... or primordial follicles could be directly visualized in situ in a neonatal ovarian section ...form primordial follicles ...in primordial follicles at 1 dpp were arrested at the ...
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No association between polymorphisms in PTEN and primary ovarian insufficiency in a Han Chinese population
... remaining primordial follicles remain in a dormant state and wait for further develop- ment or undergo apoptosis directly from dormancy ...of primordial follicles leads to a gradual ...
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Ultrastructure of ovarian preantral follicles and corpus luteum in Indian flying fox Pteropus giganteus (Brünnich)
... preantral follicles The study revealed that primordial graffian follicle (type-1) was composed of an oocyte surrounded by incomplete layer of 4–5 flattened and poorly differentiated granulosa cells resting ...
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Short-term culture of adult bovine ovarian tissues: chorioallantoic membrane (CAM) vs. traditional in vitro culture systems
... Like other techniques, the CAM culture system has few disadvantages and limitations. Special training is re- quired on eggshell windowing and chorioallantoic mem- brane preparation for ovarian tissue grafting. The ...
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Primordial follicle activation in the ovary of Ames dwarf mice
... Background: The insulin receptor substrate 1 (IRS1), phosphoinositide 3-kinase (Pi3k), protein kinase B (Akt1), Forkhead Box O3a (FOXO3a) pathway is directly involved in aging and ovarian activation of follicle growth. ...
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In vivo fate mapping of cryopreserved murine ovarian grafts
... Primordial follicles have been reported to have toler- ance to cryopreservation because of their relative abun- dance (90% of the ovary by mass), relatively inactive metabolic rate, small size and absence ...
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The expression of cyclin-dependent kinase inhibitors p15, p16, p21, and p27 during ovarian follicle growth initiation in the mouse
... Factors regulating the expression of p16 are unknown. Re- cent work has shown that p16 expression may be regulat- ed by Jun family of transcription factors. Interestingly, jun family of transcription factors play an ...
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The nuage mediates retrotransposon silencing in mouse primordial ovarian follicles
... in primordial follicles of mouse ...wild-type primordial follicles (P5 ovary) but undetectable in Mvh mutants (E ⬙ ...in primordial follicles of P5 wild-type (H) and Mvh mutant ...
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