primordial germ cell origin
The distribution and behavior of extragonadal primordial germ cells in Bax mutant mice suggest a novel origin for sacrococcygeal germ cell tumors
... extragonadal germ cells in the mouse explain these correlations? To a certain extent, they ...extragonadal germ cells in the ...the germ line, have a lower incidence of entry into meiosis, and retain ...
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How to make a primordial germ cell
... the origin of PGCs by clonal analysis (Lawson and Hage, ...demarcates germ cells from the neighbouring somatic cells through the repression of the incipient mesodermal programme (Hayashi et ...
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Primordial germ cells: the first cell lineage or the last cells standing?
... the origin and timing of the signals that initiate PGC commitment are largely unknown (Saitou and Yamaji, 2010; Irie et ...that cell-intrinsic events governing the specification of human PGCs are also ...
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Deciphering molecular mechanisms that regulate programmed cell death of primordial germ cells in Drosophila melanogaster
... Developing primordial germ cells (PGCs) share many characteristics in common with metastatic ...epithelial cell layers, migration from their site of origin to distant target tissues, and ...
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A germ cell origin of embryonic stem cells?
... early germ cells is that the very earliest events of ES cell differentiation into somatic and extra- embryonic lineages will not accurately reflect events that normally occur in ...neural cell types. ...
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The problem of the origin of primordial germ cells (PGCs) in vertebrates: historical review and a possible solution
... the primordial ectomesenchyme is considered as the material which first moved inside producing the transformation of a monoblastic ancestor (Blastaea) in the first diploblastic ...of germ cells (which in ...
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Primordial germ cell biology at the beginning of the XXI Century
... their origin in the gonads, and their migration and differentiation within the gonadal ...the germ line is determined in the early embryo; 2) the mechanism by which PGCs migrate from the ...
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DNA methylation is a primary mechanism for silencing postmigratory primordial germ cell genes in both germ cell and somatic cell lineages
... female germ cells, as XXY male germ cells also possess this reactivation capability (Mroz et ...migratory germ cells carry parent-of-origin-specific imprinting marks and high levels of ...
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Distinguishing between Germinomas and Pineal Cell Tumors on MR Imaging
... pineal cell origin tumors, that is, pineoblastoma and pineocytoma, are less frequently seen (ap- proximately 28% of the total) 3 and are believed to be differen- tiated from other cell types by their ...
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Steel factor controls primordial germ cell survival and motility from the time of their specification in the allantois, and provides a continuous niche throughout their migration
... stem cell populations, such as male and female stem cells in the gonad, epidermal stem cells and hemopoietic stem cells, signals that control pluripotency and behavior are provided by the ‘niche’ in which the stem ...
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Cellular and molecular aspects of mouse primordial germ cell migration and proliferation in culture
... Int I Un BioI 36 205 213 (1992) Review Cellular and molecular aspects of mouse primordial germ cell migration and proliferation in culture MASSIMO DE FELlCI*, SUSANNA DOLCI and MAURIZIO PESCE Departme[.] ...
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Primordial germ cell development: is the urodele pattern closer to mammals than to anurans?
... Int I I) ,' Riol ~O 653 659 (19961 653 Primordial germ cell development is the urodele pattern closer to mammals than to anurans? MASAMI WAKAHARA* Biological Sciences, Graduate School of Science Hokka[.] ...
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The zinc finger transcriptional repressor Blimp1/Prdm1 is dispensable for early axis formation but is required for specification of primordial germ cells in the mouse
... programmed cell growth and differentiation during development are controlled by master regulatory genes that coordinate the activities of cell-type- specific transcription ...its cell-type-specific ...
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Steel factor controls midline cell death of primordial germ cells and is essential for their normal proliferation and migration
... the primordial germ cells (PGCs) occupy sequentially different tissues of the ...the germ cells (Anderson et ...(E)7.5, germ cells emerge from the posterior primitive streak region of the ...
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Fish Stem Cell Cultures
... ES cell nuclei into non-enucleated mature oocytes, we generated Holly, the first semi-cloned fish in the ...ES cell nuclear transfer is comparable to that of sperm nuclear transfer ...
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A possible role of Reproductive homeobox 6 in primordial germ cell differentiation
... stem cell (ESC) line harboring EGFP driven by the Oct3/4 promoter allows the monitoring of the differentiation of primordial germ cells (PGCs) in real ...
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Drosophila primordial germ cell migration requires epithelial remodeling of the endoderm
... Trans-epithelial migration describes the ability of migrating cells to cross epithelial tissues and occurs during development, infection, inflammation, immune surveillance, wound healing and cancer metastasis. Here we ...
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The allocation and differentiation of mouse primordial germ cells
... mediating cell- cell interaction and ...of germ cells in the fetal gonad (Buehr et al, ...the germ cell lineage by mediating the inductive tissue interaction between the extraembryonic ...
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Vol 71, No 4 (2019)
... Primordial germ cells were determined from the first day post fertilization (dpf) and migration routes were observed in both control and exposure ...
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Mouse primordial germ cells produce cysts that partially fragment prior to meiosis
... mouse germ cells (Pepling and Spradling, ...E10.5 germ cells that develop into cysts will form clones of a size (number of cells) that is a power of two due to mitotic synchrony, whereas the clone size of ...
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