proneural gene
Rough eye Is a Gain-of-Function Allele of amos That Disrupts Regulation of the Proneural Gene atonal During Drosophila Retinal Differentiation
... the proneural gene atonal (ato), which is responsible for the specification of the ommatidial founder cells ...bHLH gene amos that results from a chromosomal ...
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Drosophila optic lobe neuroblasts triggered by a wave of proneural gene expression that is negatively regulated by JAK/STAT
... the proneural gene ...lobe proneural wave is reminiscent of the morphogenetic furrow that moves across the developing eye imaginal ...the proneural wave still progresses even when NB ...
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Tufted Is a Gain-of-Function Allele That Promotes Ectopic Expression of the Proneural Gene amos in Drosophila
... of proneural Jan and Jan 1993; Jarman et ...external Proneural genes confer to cells the capacity to become SOs, like the bristles and sensilla campaniformia and sensory organ precursors ...each ...
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SoxB1 transcription factors and Notch signaling use distinct mechanisms to regulate proneural gene function and neural progenitor differentiation
... of proneural proteins to promote ...of proneural- and E- protein expression, to ascertain that the correct number of cells initiate neuronal differentiation at a specific stage ...
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The proneural gene ascl1a is required for endocrine differentiation and cell survival in the zebrafish adenohypophysis
... stages, and is set up normally in pia mutants, as revealed by in situ hybridization against eya1 transcripts (data not shown) (cf. Herzog et al., 2004a). Specification of the pituitary itself starts around 19 hpf, as ...
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Characterization of the proneural gene regulatory network during mouse telencephalon development
... a gene considered as directly regulated by Ngn pro- teins [19], was decreased in the Ngn2-/- embryos, but was not significantly upregulated after Ngn2 electroporation in microarray experiments, suggesting that the ...
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Induction and autoregulation of the anti proneural gene Bar during retinal neurogenesis in Drosophila
... undifferentiated cells: posterior margin signal (Hh) and furrow signal (blue arrow). P, posterior margin; MF, morphogenetic furrow. (D-F) Ato is required for Bar expression. Bar expression is absent (white arrow) ...
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Drosophila Tufted Is a Gain-of-Function Allele of the Proneural Gene amos
... these proneural proteins though primarily only in the wing pouch region (Figure to activate the mechanosensory organ is probably not due 7D, ...normal proneural bHLHs for activated either Amos or Ato ...
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Recruitment of the Proneural Gene scute to the Drosophila Sex-Determination Pathway
... and proneural functions of scute began with the termination triplet would belong to the inserted coding the recovery of two new sc alleles that were unlike any region of interest, but everything more 3⬘ would be ...
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her3, a zebrafish member of the hairy E(spl) family, is repressed by Notch signalling
... same effect has been reported after misexpression of a Xenopus Notch variant (Coffman et al., 1993), and following misexpression of deltaD (Dornseifer et al., 1997) and her4 (Takke et al., 1999) in the zebrafish. The ...
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Lunatic fringe promotes the lateral inhibition of neurogenesis
... of proneural knockdown or misexpression on lfng expression is that they are secondary to the regulation of Delta/Serrate genes that activate ...If proneural genes (or downstream transcription factors) ...
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Proper connectivity of Drosophila motion detector neurons requires Atonal function in progenitor cells
... as proneural proteins [9-11]. There are two major classes of proneural proteins, called the Achaete-Scute (AS) family and the Atonal (Ato) family, after their founding ...a proneural gene in ...
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Evolution of cis regulation of the proneural genes
... of proneural protein for a considerable time after the proneural domains have faded and before the initiation of metamorphosis and bristle ...of proneural protein through stochas- tic processes would ...
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Establishment of a proneural field in the inner ear
... a proneural field expressing Neurog1 is distinguished in an anterior subdomain of the otic ...the proneural field in zebrafish, chick and mice, their function prob- ably also related to the recruitment of ...
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Drosophila Notch receptor activity suppresses Hairless function during adult external sensory organ development.
... In addition to proneural gene function, production of adult external sensory organs requires Hairless ( H ) activ- ity (BANG et al. We were interested in the phenotyp[r] ...
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R8 development in the Drosophila eye: a paradigm for neural selection and differentiation
... both proneural gene expression and differentiation are rescued non- autonomously near the borders of Dl clones, it seems that proneural enhancement is a specific function of cells in which Notch ...
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Determination of cell fate along the anteroposterior axis of the Drosophila ventral midline
... The ventral midline provides an ideal system for a comprehensive genomic approach to the development of a CNS organiser. This is because of the limited number of midline precursors, which give rise to only a few neuronal ...
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An arthropod cis-regulatory element functioning in sensory organ precursor development dates back to the Cambrian
... reporter gene fusion constructs that cover different regions upstream of the ORF only restrict expression to single SOPs if the 560-bp UTR containing the SOPE is present [13], the ORF+SOPE constructs should reduce ...
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Neurogenesis in the sea urchin embryo is initiated uniquely in three domains
... six proneural transcription factors were selected: three that are expressed in all three neural territories (soxC, sip1, soxb1) and three that are expressed in one or two of the territories but not all three, at ...
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Partially redundant proneural function reveals the importance of timing during zebrafish olfactory neurogenesis
... only gene for which expression fails to recover in residual EONs in the neurog1 ...after proneural gene activity drives them to differentiate is a crucial parameter for the correct acquisition of EON ...
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