proof-of-principle study
Safety and applicability of a pre-stage public access ventilator for trained laypersons: a proof of principle study
... The intention of this project was to develop an auto- mated ventilator in order to support laypersons, who are willing to perform rescue ventilation in patients with sudden cardiac arrest. The functional prototype of the ...
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Impairment targeted exercises for older adults with knee pain: a proof of principle study (TargET Knee Pain)
... The observed changes can be viewed in the context of changes seen in previous studies of exercise for knee pain and osteoarthritis. A systematic review of exercise for lower limb osteoarthritis found the most effective ...
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Training working memory to improve attentional control in anxiety: a proof of principle study using behavioral and electrophysiological measures
... regulation of top-down control mechanisms, thereby resulting in decreased interference from bottom-up influences in trait vulnerability to anxiety. Despite such improvements in performance and resting state EEG, the ...
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Electronic Nose Technology for Detection of Invasive Pulmonary Aspergillosis in Prolonged Chemotherapy Induced Neutropenia: a Proof of Principle Study
... Although the high mortality rate of pulmonary invasive aspergillosis (IA) in patients with prolonged chemotherapy-induced neutropenia (PCIN) can be reduced by timely diagnosis, a diagnostic test that reliably detects IA ...
6
The NuGO proof of principle study package: a collaborative research effort of the European Nutrigenomics Organisation
... this study is to generate robust omics data sets for the effects of diets comprised of increasing fat contents on the ...core study was performed at Wa- geningen University (coordinated by ...
5
Impairment targeted exercises for older adults with knee pain: protocol for a proof of principle study
... Methods/Design: We aim to recruit 60 participants from an existing observational cohort of community-dwelling older adults with knee pain. Participants will all have at least one of the three physical impairments of weak ...
7
Placental Homing Peptide-microRNA Inhibitor Conjugates For Targeted Enhancement Of Intrinsic Placental Growth Signalling
... this proof of principle study, we explored the feasibility of delivering miRNA inhibitors to the placentas of pregnant mice and developed novel placental homing peptide-microRNA inhibitor conjugates ...
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Discriminating lymphomas and reactive lymphadenopathy in lymph node biopsies by gene expression profiling
... This proof of principle study has shown that microarray as a single platform assay can achieve reasonable diag- nostic accuracy with the ability to differentiate lym- phoma from non-cancerous ...
10
Follicular fluid biomarkers for human in vitro fertilization outcome: Proof of principle
... This study aimed to reveal if peptide profiling of individual FF could become a new non-invasive predictive biomarker for oocyte quality, and attempted to discover candidate biomarkers for ...
11
A Rapid Matrix Assisted Laser Desorption Ionization–Time of Flight Mass Spectrometry Based Method for Single Plasmid Tracking in an Outbreak of Carbapenem Resistant Enterobacteriaceae
... this study were obtained using bacterial protein extracts, the pKpQIL_p019 MALDI-TOF MS peak was also observed in samples using a direct bacterial spotting technique with 70% formic acid overlay (data not ...
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<p>Treating and teaching: using publicly available data to explore the relationship between student and patient evaluations of teaching hospitals</p>
... this proof-of-principle study, we used publicly avail- able data to correlate patient evaluations of a training site with student evaluations of the educational experi- ences at that ...This ...
5
Bayesian probit regression model for the diagnosis of pulmonary fibrosis: proof-of-principle
... We acknowledge the limitations of our study. Our pro- visional models range from 63-83% accurate. The present study was performed on a small cohort and was only intended as a ...
13
On maximal inequalities via comparison principle
... In the next section, using a comparison principle, a two-sided explicit estimate of the maximal solution y → g ∗ (y) of () is given based on the maximal and minimal solutions of (). Our main emphasis is on the ...
5
Radiofrequency hyperthermia promotes the therapeutic effects on chemotherapeutic-resistant breast cancer when combined with heat shock protein promoter-controlled HSV-TK gene therapy: Toward imaging-guided interventional gene therapy
... this study, tumor growth was followed up for up to two weeks and combination therapy did not prolong overall survival after the ...this study grew fast, posing the risk that those in the control group could ...
10
Transposable element invasions
... T ransposable elements have an ongo- ing, largely parasitic interaction with their hosts. We are interested in the tim- escale of this interaction. In a recent pub- lication, we have examined the sequence divergence ...
5
Airway exposure to multi-walled carbon nanotubes disrupts the female reproductive cycle without affecting pregnancy outcomes in mice
... the study period were noted and used for analyses, apart from one control and one exposed female that were completely excluded from the analysis as they displayed only one cycle each, with durations of 27 and 22 ...
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Efficacy and safety of guaifenesin for upper back, neck, and shoulder pain: a Phase II proof-of-concept, multicenter, placebo-controlled, repeat-dose, parallel-group study
... 7-day study period, treatment with guaifenesin 1200 mg BID provided numerically greater improvements than its matched placebo and guaifenesin 600 mg BID on most other subject-reported symptoms, including pain ...
10
The NOTHING ELSE Brand: A Case Study
... A major limitation of this case study is the small number of participants who completed the questionnaires. As a proof of principle this ongoing project has a number of strengths. The AUT University ...
7
Association between genetic variants in the Coenzyme Q10 metabolism and Coenzyme Q10 status in humans
... higher in E4/E4 carriers as compared to all other geno- type groups, however p values did not reached signifi- cance (p = 0.065, E2/E3 vs E4/E4, Figure 2). These results confirm the results found by Battino et al [29] in ...
7
A randomised controlled trial of intravenous zoledronic acid in malignant pleural disease: A proof of principle pilot study
... CT is the current gold standard imaging modality for evaluation of the pleura and the modi- fied RECIST criteria have been developed to stage and monitor treatment response in mesothe- lioma [21, 22]. Unidimensional ...
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