protein and peptides
Properties and formulation of oral drug delivery systems of protein and peptides
... most protein pharmaceuticals are usually formulated as a solution or suspension and delivered by invasive routes such as subcutaneous injections, major efforts in both academic and industrial laboratories have ...
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Design of protein segments and peptides for binding to protein targets
... designing peptides is that the structure-function link that is often very prominent in functional proteins is blurry for ...functional peptides are intrinsically disordered or sample multiple ...novel ...
Using Peptidomimetics and Constrained Peptides as Valuable Tools for Inhibiting Protein⁻Protein Interactions.
... Abstract: Protein–protein interactions (PPIs) are tremendously important for the function of many biological ...many protein–protein interfaces (flat, featureless and relatively large), they ...
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Efficient conformational ensemble generation of protein-bound peptides
... for peptides with 3–20 amino acids or provides a good starting point of docking + MD pro- tocols for peptides with more than 20 amino ...some peptides even when an ensemble of 1000 conformations were ...
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Modification Of Soy Protein For The Production Of Bioactive Peptides And Their Utilization
... vegetable protein that is often consumed to meet the needs of protein in the body since it is rich in various essential amino ...soy protein has various advantages if it is consumed in a simpler form ...
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The CFTR-derived peptides as a model of sequence-specific protein aggregation
... the peptides’ ability to aggregate in transfected IB3-1 cells was noticeably different from the outcome produced by the ag ...HR3 peptides was never as high as in the case of the original peptide with the ...
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Systematic errors in peptide and protein identification and quantification by modified peptides
... modified peptides and therefore neglects potentially useful ...modified peptides identified in the modified ...modified peptides and bas- ing quantification on them is not always useful for two rea- ...
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Signal peptides for recombinant protein secretion in bacterial expression systems
... signal peptides that significantly increased the amounts of the heterologous target protein cutinase from ...signal peptides actually slowed down the translocation of the cutinase across the ...
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Competition between bound and free peptides in an ELISA-based procedure that assays peptides derived from protein digests
... the protein to be ...Next, peptides 7–15 amino acid long were ...hydrophilic peptides as being those that would be most likely to be good antigens ...selected peptides were ultimately chosen ...
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Erythrina edulis (Pajuro) seed protein: a new source of antioxidant peptides
... of protein at the end of proteolysis. Similarly, rapeseed protein hydrolyzates with Flavourzyme ® showed low ORAC values that were attributed to the release of large-size peptides that did not ...
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The DNAJB6 and DNAJB8 Protein Chaperones Prevent Intracellular Aggregation of Polyglutamine Peptides
... polyQ peptides than when initiated by Htt- exon-1 ...polyQ peptides. Thereby they prevent that polyQ peptides can act as nucleators of aggregation and subsequent sequestering of larger ...
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Preparation and characterization of antibodies against mouse prion protein (PrP) peptides.
... three peptides, representing amino acid sequences 150 to 159, 165 to 174, and 213 to 226 of mouse prion protein (PrP), which were synthesized by using a multiple antigenic peptide (MAP) ...
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Screening of soy protein-derived hypotriglyceridemic di-peptides in vitro and in vivo
... bioactive peptides have been produced in vitro through chemical or enzymatic hydrolysis of several food proteins, in order to modify and improve the physiological functions of dietary proteins ...Bioactive ...
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Protein inference based on peptides identified from tandem mass spectra
... In the second phase, peptides are identified by matching MS/MS data to peptide sequences in the database. Since there are already many well-developed search engines performing the work of peptide-spectrum-match ...
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Rational design of a carrier protein for the production of recombinant toxic peptides in Escherichia coli
... bioactive peptides require low cost, effective methods for their produc- ...carrier protein for high yield production of recombinant peptides in Escherichia coli very well suited for the production ...
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Protein hydrolysates in animal nutrition: Industrial production, bioactive peptides, and functional significance
... of protein hydrolysates as flavor enhancers, functional ingredients, and precursors for protein synthesis depends on the composition of free AAs, small peptides and large peptides in the ...
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Crytic antimicrobial peptides hidden in protein precursors: identification of novel bioactive molecules
... a protein that, although not yet been characterized, could be constitutively present under physiological conditions and able to release, by induced proteolysis, a fragment containing GVF27 in response to pathogen ...
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A feedback framework for protein inference with peptides identified from tandem mass spectra
... corresponding peptides at the same time, and it is achieved by iteratively updating the two lists with a feed- back from the inferred proteins to the selection of correct ...inferred protein sequences are ...
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Functional screening system for yeast-secreted peptides acting on G-protein coupled receptors
... for peptides acting on G-protein coupled receptors ...intracellular protein–protein ...novel peptides act- ing on GPCRs, but it is unclear whether the identified peptides ...
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