protein kinase pathways
Mitogen Activated Protein Kinase Pathways Following Traumatic Brain Injury
... can all cause cells to undergo apoptosis, in vitro studies have determined that neuronal cells can undergo apop- tosis via many other pathways. However, the biochemi- cal cascades underlying posttraumatic signal ...
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Reactive oxygen species regulate urokinase plasminogen activator expression and cell invasion via mitogen-activated protein kinase pathways after treatment with hepatocyte growth factor in stomach cancer cells
... transduction pathways, such as MAPK, PI3K, and the Rho-GTPase cascades, are known to mediate transcrip- tional regulation of metastasis-related genes, such as MMPs ...
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Mitogen-Activated Protein Kinase Pathways and Fungal Pathogenesis
... receptor kinase genes that function upstream from Ras in mammalian ...scaffold protein in pathogenic fungi has been ...MAPK pathways and their downstream targets or net- work of transcription ...
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Retinoic acid inhibits induction of c Jun protein by ultraviolet radiation that occurs subsequent to activation of mitogen activated protein kinase pathways in human skin in vivo
... tRA is an important regulator of cellular homeostasis in many tissues, including human skin. The actions of tRA are mediated by nuclear retinoid receptors that are ligand-acti- vated transcription factors (36). In mouse ...
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Glucocorticoids: do we know how they work?
... activator protein-1 and ...the protein inhibitor of NF- κ ...mitogen-activated protein kinase pathways that mediate the expression of inflammatory ...
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Intercellular junctional proteins as targets for protein kinase c-mediated signalling pathways
... this protein decrease permeability to ions, whilst at the same time increasing permeability to larger tracers? The theory that tight junctions consist of a series of diffusion barriers, each with a fluctuating ...
192
Tyrosine kinases in rheumatoid arthritis
... also noted. Pamapimod (RO4402257; Hoffmann-La Roche, Basel, Switzerland), a p38a inhibitor with very low p38b inhibitory activity, is another drug tested for poten- tial efficacy against RA. In spite of the promising ...
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Platelets decrease chemotherapy induced cancer cell damage by increasing cell survival : mechanisms and significance
... main pathways of apoptosis: the death receptor pathway and the death mitochondrial ...p53 protein, which is responsible for activation of subpathway in the ...p21 protein and anti-apoptotic members ...
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Original Article Association detection between genetic variants in the microRNA binding sites of toll-like receptors signaling pathway genes and bladder cancer susceptibility
... Bladder cancer (BCa) accounts for approxi- mately 2% of all human malignancies and it has the highest incidence and mortality rate among urinary system tumors [1, 2]. In China, the occurrence of BCa has dramatically ...
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Modulation of NOX4 and MAPK Signaling Pathways by Parkia speciosa Empty Pods in H9c2 Cardiomyocytes Exposed to H2O2
... the protein expression of NADPH oxidase 4, superoxide dismutase 1 and p38 mitogen-activated protein kinase, in comparison to the negative ...mitogen-activated protein kinase and NADPH ...
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Murine Cytomegalovirus Virion-Associated Protein M45 Mediates Rapid NF-κB Activation after Infection
... M45 protein is a very potent inhibitor of NF-B acti- ...mitogen-activated protein kinase ...activation pathways and in the suppression of proinflammatory cytokine ...adaptor kinase ...
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Original Article Propranolol induces apoptosis in endothelial cells by inhibiting Akt and ERK phosphorylation and MAPK signaling pathway
... signaling pathways play important roles in the anti-apoptotic process of ...MAPK pathways, but not the proliferation of ...dent kinase 4 (CDK4), leading to cell prolifera- tion or ...enzymes, ...
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Flavonoids in modulation of cell survival signalling pathways
... signalling pathways espe- cially during various diseases (Fu et ...signalling pathways by use of various natural ...signalling pathways have come to be appreciated as attrac- tive targets for drug ...
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Increased A20-E3 ubiquitin ligase interactions in bid-deficient glia attenuate TLR3- and TLR4-induced inflammation
... mitogen-activated protein kinases (MAPK) and interferon regulatory factor 3 (IRF3) ...binding kinase 1 (TBK1) and the subsequent association with the IKK subunit I B kinase ε (IKKε) to activate the ...
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Protein Kinase A and High Osmolarity Glycerol Response Pathways Cooperatively Control Cell Wall Carbohydrate Mobilization in Aspergillus fumigatus
... the protein kinase A (PKA) pathway ...synthase kinase has been proposed to be a target for treating invasive aspergillosis as it is important for Aspergillus growth ...
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Role of Rho GTPases and PTEN in the migration of human glioma cells
... Tumor suppressor PTEN inhibits integrin- and growth factor-mediated mitogen-activated protein (MAP) kinase signaling pathways, J Cell Biol 143,1375-83. Proliferation[r] ...
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The Enigmatic X Gene of Hepatitis B Virus
... a protein which protects against TNF and Fas-mediated apoptosis, and this association might pro- duce yet another potential molecular explanation for HBx sen- sitization of hepatocytes to TNF apoptotic activity ...
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Cross Talk between the Cell Wall Integrity and Cyclic AMP/Protein Kinase A Pathways in Cryptococcus neoformans
... kinases, protein kinase C (Pkc1), bypass of pro- tein kinase C (Bck1), mitogen-activated kinase kinase (Mkk2), and mitogen-activated protein kinase (Mpk1), all of which ...
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English_unc_0153D_14626.pdf
... of protein-state clustering necessary to understand communication ...own protein network signature, and these could be overlayed to identify nodes of ...
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Androgen receptor signaling in prostate cancer development and progression
... The human AR gene is a nuclear transcription factor and a member of the steroid hormone receptor superfamily of genes. It is located on the X chromosome (q11-12) and consists of 8 exons. It codes for a protein of ...
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