Protein-Ligand Interactions
Compact, Polyvalent Mannose Quantum Dots as Sensitive, Ratiometric FRET Probes for Multivalent Protein-Ligand Interactions
... multivalent interactions of HIV/Ebola receptors DC-SIGN and DC-SIGNR (collectively termed as DC-SIGN/R) via a sensitive, ratiometric F ö rster resonance energy transfer (FRET) ...multivalent ...
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3D-QSAR study of steroidal and azaheterocyclic human aromatase inhibitors using quantitative profile of protein–ligand interactions
... of protein–ligand interactions was employed in the identification and characterization of critical steric and electronic features of aromatase-inhibitor complexes and the estimation of their ...
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Compact, Polyvalent Mannose Quantum Dots as Sensitive, Ratiometric FRET Probes for Multivalent Protein–Ligand Interactions
... multivalent interactions of HIV/Ebola receptors DC-SIGN and DC-SIGNR (collectively termed as DC-SIGN/R) using a sensitive, ratiometric Fçrster resonance energy transfer (FRET) ...multivalent ...
6
Hydrogen Exchange Mass Spectrometry for Studying Protein- Ligand Interactions
... of protein-ligand ...truncated protein variants with enhanced crystallization ...of ligand-induced stabilization, but interestingly there is also a long sequence stretch that becomes more ...
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Compact, Polyvalent Mannose-Quantum Dots as Sensitive, Ratiometric FRET Probes for Multivalent Protein-Ligand Interactions
... multivalent interactions of HIV/Ebola receptors DC-SIGN and DC-SIGNR (collectively termed as DC-SIGN/R) using a sensitive, ratiometric Fçrster resonance energy transfer (FRET) ...multivalent ...
5
DLIGAND2: an improved knowledge-based energy function for protein–ligand interactions using the distance-scaled, finite, ideal-gas reference state
... target protein to the dataset for training the ...on protein targets that are not homologous to its training ...only protein monomer structures, ensur- ing a balanced performance for all ...
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Protein ligand interactions: docking, design and protein conformational change
... dimeric protein and the crystal structures of ...native ligand, methionine, have been solved to ...MetRS protein structure as apo-MetRS(crystal) and the co-crystal structure of ...the protein ...
353
Protein Ligand Interactions by NMR and EPR Spectroscopy
... the protein with two different fluorescent labels, where one label acts as a donor and the other as an ...makes protein labelling more cumbersome (Seo et ...upon ligand binding in solution or can be ...
206
A bayesian kernel for the prediction of protein-protein interactions
... a protein in order to understand its ...predict protein-protein ...predict protein-protein ...experimental protein-protein interactions data that were compiled from ...
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The interactome: Predicting the protein-protein interactions in cells
... of protein-protein interactions is a difficult problem when an analysis of both the protein sequences and known three-dimensional structures is ...possible interactions that have to be ...
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Role of electrostatic interactions for ligand recognition and specificity of peptide transporters
... These interactions of the transporter with the dipeptide backbone, which are dipep- tide side chains independent interactions, can be consid- ered as responsible for the substrate polyspecificity ...
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Extracting Protein-Protein Interactions with Language Modelling
... In this paper we have presented and experimented several systems, that can be easily implemented, to extract directed Protein-Protein Interactions in bio-medical texts. We have shown that modeling ...
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Computational Design Of Protein–ligand And Protein–protein Interactions
... recognition. Protein–ligand and protein–protein interactions make up the bulk of the chemical processes that give rise to living ...of protein design technology will therefore ...
196
Extracellular interactions and ligand degradation shape the nodal morphogen gradient
... and protein G dynabeads (Life Tech- nologies), and eluted with 3xFLAG peptide ...individual protein bands was nor- malized against EGFP to correct for differences in sample volume and immunoprecipitation, ...
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1H and 13C MAS NMR Evidence for Pronounced Ligand-Protein Interactions Involving the Ionone Ring of the Retinylidene Chromophore in Rhodopsin
... nearby protein residue (3, 4, 33, ...ing protein (47, 48). Although these studies indicate strong ligand–protein interactions for CH 3 -19, it is clear from the ...
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LILRB1 polymorphisms influence posttransplant HCMV susceptibility and ligand interactions
... LILRB1 polymorphisms and HCMV viremia in transplant patients. To test whether LILRB1 genotype influences HCMV susceptibil- ity, we analyzed LILRB1 genotypes in a small group of Canadian transplant patients (22). The ...
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Modeling and disrupting protein interactions
... cellular protein networks that produce directly correlating differential expression ...actual protein target(s) and/or for genes up/downstream of the ...molecular interactions [84, ...likely ...
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Protein nanoparticles with ligand-binding and enzymatic activities
... Fluorescent protein NP can be used in cellular research and ...BSA-RhoB protein and the corresponding fluorescent NP were comparable with the wide range of anti-BSA antibodies dilution from 1:10 to 1:10,000 ...
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Chemokine ligand–receptor interactions critically regulate cutaneous wound healing
... Approximately, 4 days after injury granulation tis- sue invades the wound bed. Fibroblasts start to produce a provisional matrix composed of fibrin, fibronectin, and hyaluronic acid, which is necessary to support cell ...
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Structural Basis of Ligand Interactions of the Large Extracellular Domain of Tetraspanin CD81
... fusion protein template while integrating disulfide connectivity, functional, and secondary structure data ...lope protein heterodimerization as well as in virus ...E2 protein for HCV ...to ...
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