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Proteomics Technology

Identification of potential serum biomarkers for breast cancer using a functional proteomics technology

Identification of potential serum biomarkers for breast cancer using a functional proteomics technology

... functional proteomics technology was developed that can analyze the function of serum proteins systematically after 2-D gel electrophoresis ...this technology, it was demon- strated that the ...

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Research on the Rice Proteome: The Contribution of Proteomics Technology in the Creation of Abiotic Stress-Tolerant Plants

Research on the Rice Proteome: The Contribution of Proteomics Technology in the Creation of Abiotic Stress-Tolerant Plants

... of proteomics studies on stressed crops have been performed on rice [50]; furthermore, more than 50% of proteomics studied on rice involve salt or cold ...

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Investigation of post-translational modifications in type 2 diabetes

Investigation of post-translational modifications in type 2 diabetes

... based proteomics technology has provided an opportunity to study proteins, their PTMs like phosphorylation, acetylation, N-glycosylation, O-GlcNAcylation and Advanced glycation end products in type 2 ...

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Exploring the Human Seminal Plasma Proteome: An Unexplored Gold Mine of Biomarker for Male Infertility and Male Reproduction Disorder

Exploring the Human Seminal Plasma Proteome: An Unexplored Gold Mine of Biomarker for Male Infertility and Male Reproduction Disorder

... The proteome of the seminal plasma is complex and contains some high abundance proteins in- cluding semenogelins and kallikrein 3 (also known as prostate specific antigen). Progress in biological mass spectrometry has ...

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Proteomic Applications in Antimicrobial Resistance and Clinical Microbiology Studies

<p>Proteomic Applications in Antimicrobial Resistance and Clinical Microbiology Studies</p>

... Aaminoacyl tRNA binding to the mRNA-ribosome com- plex can be inhibited by tetracycline. 188 There are at least three mechanisms that create cell resistance to tetracycline including enzymatic inactivation of ...

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PROTEOMICS OF CHONDROGENESIS: A REVIEW

PROTEOMICS OF CHONDROGENESIS: A REVIEW

... Ji et. al . applied a gel free isobaric tag for relative and absolute quantitation (iTRAQ) labeling coupled with 2D LC/ MS/MS proteomics technology to quantitate the protein expression profile of an in ...

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Quantitative proteomics in lung cancer

Quantitative proteomics in lung cancer

... iTRAQ-labeling technology coupled with 2D-LC-MS/ MS ...quantitative proteomics identified several biomarkers by comparing the protein abundance of immortalized normal epithelial cell derived exosomes and ...

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Proteomics Metagenomics and Deterministic Annealing

Proteomics Metagenomics and Deterministic Annealing

... • System becomes unstable as Temperature lowered and there is a phase transition and one splits cluster into two and continues EM iteration • One can start with just one cluster and need[r] ...

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Saliva proteomics updates in biomedicine

Saliva proteomics updates in biomedicine

... The key technology of proteomics is mass spectrom- etry (MS) supported by bioinformatics tools for data acquisition and management [24]. However, the most critical steps in every proteomic experiment are ...

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Clinical proteomics of myeloid leukemia

Clinical proteomics of myeloid leukemia

... clinical proteomics, and selected tools are presented, including stable isotope labeling with amino acids in cell culture (SILAC), isobaric tags for relative and absolute quantification (iTRAQ) and multiple ...

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Dynamic Proteomics of Herpes Simplex Virus Infection

Dynamic Proteomics of Herpes Simplex Virus Infection

... ABSTRACT The cellular response to viral infection is usually studied at the level of cell populations. Currently, it remains an open question whether and to what extent cell-to-cell variability impacts the course of ...

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Characterization of Anti-Salmonella enterica Serotype Typhi Antibody Responses in Bacteremic Bangladeshi Patients by an Immunoaffinity Proteomics-Based Technology

Characterization of Anti-Salmonella enterica Serotype Typhi Antibody Responses in Bacteremic Bangladeshi Patients by an Immunoaffinity Proteomics-Based Technology

... In summary, IPT is a rapid screening tool that can be used to identify proteins that elicit a serological immune response in infected hosts. Using this technology, we identified a number of immunogenic proteins of ...

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Feasibility of Utilizing Stable-Isotope Dimethyl

Feasibility of Utilizing Stable-Isotope Dimethyl

... Stable-isotope dimethyl labeling, as a chemical labeling method for quantitative proteomics, is.. 45.[r] ...

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Male Infertility, Precision Medicine and Systems Proteomics

Male Infertility, Precision Medicine and Systems Proteomics

... term proteomics, which means a high-throughput analysis of proteins, was introduced in 1997 (12, 30, ...of proteomics include the pro- tein content or a variety of proteins expressed in different ...PM. ...

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Approaches for Improved Positional Proteomics

Approaches for Improved Positional Proteomics

... A method using biotinylation to positive select N-terminal peptides was reported by Kuhn et al in 2003. 49 This protein tag technology was later on adapted and further developed by the Salvesen lab to identify ...

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APPLICATIONS OF PROTEOMICS IN ANIMAL MODEL

APPLICATIONS OF PROTEOMICS IN ANIMAL MODEL

... system. Proteomics encompasses the analysis of protein expression, protein structure and protein ...cell. Proteomics is much more complicated than genomics mostly because, an organism‘s whole genome is more ...

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Leishmania Proteomics: an in silico perspective

Leishmania Proteomics: an in silico perspective

... A gold-containing drug against parasitic polyamine metabolism: the X- ray structure of trypanothione reductase from Leishmania infantum in complex with auranofin reveals a dual mechanism[r] ...

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Leishmania Proteomics: an in silico perspective

Leishmania Proteomics: an in silico perspective

... Figure 4: Leishmania protein classification. The chart at the bottom right of the figure shows the number of proteins found for each species. brucei do not belong at the Leishmania prote[r] ...

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Leishmania Proteomics: An in Silico Perspective

Leishmania Proteomics: An in Silico Perspective

... major enzyme (PDB ID: 1EZR) is the main responsible of nucleotide salvaging from host, due Leishmania parasite lack de novo biosynthesis pathway. of purines[r] ...

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Proteomics - The Future of Periodontal Diagnostics

Proteomics - The Future of Periodontal Diagnostics

... in proteomics may help scientists eventually create medications that are personalized for different individuals to be more effective and have fewer side ...

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