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proximal tubular epithelial cells

Unique molecular profile of exosomes derived from primary human proximal tubular epithelial cells under diseased conditions

Unique molecular profile of exosomes derived from primary human proximal tubular epithelial cells under diseased conditions

... Human proximal tubular epithelial cells (PTEC) of the kidney are known to respond to and mediate the disease process in a wide range of kidney diseases, yet their exosomal production and ...

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The cat as a naturally occurring model of renal interstitial fibrosis: Characterisation of primary feline proximal tubular epithelial cells and comparative pro-fibrotic effects of TGF-ß1

The cat as a naturally occurring model of renal interstitial fibrosis: Characterisation of primary feline proximal tubular epithelial cells and comparative pro-fibrotic effects of TGF-ß1

... renal proximal tubular epithelial cells was modified for use in cats ...sieved cells were centrifuged for 3 min at 90 x g and resuspended in 10ml primary culture ...face). Cells ...

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Caveolar Endocytosis Is Critical for BK Virus Infection of Human Renal Proximal Tubular Epithelial Cells

Caveolar Endocytosis Is Critical for BK Virus Infection of Human Renal Proximal Tubular Epithelial Cells

... renal proximal tubular epithelial cells (HRPTEC) represent a main natural target of BKV nephritis, analysis of BKV infection of HRPTEC is necessary to obtain additional insights into BKV ...

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Interleukin 2 mediates stimulation of complement C3 biosynthesis in human proximal tubular epithelial cells

Interleukin 2 mediates stimulation of complement C3 biosynthesis in human proximal tubular epithelial cells

... the cells involved in production of complement have not been ...human proximal tubular epithelial cells (PTEC) synthesize a 180-kD precursor of C3 that ...

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Cdc42-Interacting Protein-4 Promotes TGF-Β1-Induced Epithelial-Mesenchymal Transition and Extracellular Matrix Deposition in Renal Proximal Tubular Epithelial Cells

Cdc42-Interacting Protein-4 Promotes TGF-Β1-Induced Epithelial-Mesenchymal Transition and Extracellular Matrix Deposition in Renal Proximal Tubular Epithelial Cells

... renal tubular epithelial cells can undergo EMT in vitro in response to TGFβ-1 ...renal tubular epithelial cells undergoing various de- grees of change to become local producers ...

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Albumin stimulates interleukin 8 expression in proximal tubular epithelial cells in vitro and in vivo

Albumin stimulates interleukin 8 expression in proximal tubular epithelial cells in vitro and in vivo

... stimulates tubular IL-8 expres- sion, which is dependent on the endocytosis of albu- min that triggers a cascade of intracellular signals from PKC-dependent activation of ROS generation to nuclear translocation of ...

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Everolimus induced epithelial to mesenchymal transition in immortalized human renal proximal tubular epithelial cells: key role of heparanase

Everolimus induced epithelial to mesenchymal transition in immortalized human renal proximal tubular epithelial cells: key role of heparanase

... renal epithelial proximal tubular cells ...of cells motility in WT HK2 cells treated with high concentrations of EVE (higher than 100 ...EVE-treated cells (p < ...

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Predominant role for C5b 9 in renal ischemia/reperfusion injury

Predominant role for C5b 9 in renal ischemia/reperfusion injury

... human proximal tubular epithelial cells have deficient expression of the C regula- tory proteins CD55 and CD46 (53) and can activate the alternative pathway spontaneously at low concentrations ...

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Transforming growth Factor Beta 1 drives a switch in connexin mediated cell to cell communication in tubular cells of the diabetic kidney

Transforming growth Factor Beta 1 drives a switch in connexin mediated cell to cell communication in tubular cells of the diabetic kidney

... The present study correlates altered connexin expression to altered cell function in proximal tubular epithelial cells of the diabetic kidney. Novel histological evidence, suggests that ...

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Role for integrin linked kinase in mediating tubular epithelial to mesenchymal transition and renal interstitial fibrogenesis

Role for integrin linked kinase in mediating tubular epithelial to mesenchymal transition and renal interstitial fibrogenesis

... renal tubular epithelial cells can undergo epithelial to mesenchymal transition (EMT), a phenotypic conversion that is believed to play a critical role in renal interstitial ...ating ...

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Aged garlic extract protects against oxidative stress and renal changes in cisplatin-treated adult male rats

Aged garlic extract protects against oxidative stress and renal changes in cisplatin-treated adult male rats

... the proximal tubular epithelial cells, where marked tubular degenera- tion with distinct apoptotic changes, loss of apical micro- villi, irregularity of basement membrane, rarification ...

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Significance of downregulation of renal organic cation transporter (SLC47A1) in cisplatin-induced proximal tubular injury

Significance of downregulation of renal organic cation transporter (SLC47A1) in cisplatin-induced proximal tubular injury

... human proximal tubular epithelial cells were incubated for 24 hours in serum-free renal epithelial cell growth medium (control), cell growth medium with a-HSA ...The cells were ...

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A 3-biomarker-panel predicts renal outcome in patients with proteinuric renal diseases

A 3-biomarker-panel predicts renal outcome in patients with proteinuric renal diseases

... microdissected proximal tubular epithelial cells from routine kidney biopsies were correlated with a chronic renal damage index score (CREDI), an inflammation score (INSCO), and clinical ...

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Original Article Necrotic epithelial cells in proximal renal tubules of 2 nd trimester fetuses: is this “acute tubular necrosis”?

Original Article Necrotic epithelial cells in proximal renal tubules of 2 nd trimester fetuses: is this “acute tubular necrosis”?

... multiplied, tubular injury develops, as has been documented by urinary detection of biomarkers such as cytokines (IL-6, IL-8, IL-18), NGAL, NAG, and KIM-1 ...

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In Vitro Study of the Nephrotoxicity of Tripterygium Tablet Extract and Triptolide in Monolayer HK 2 Cells Cultured in a Transwell Chamber

In Vitro Study of the Nephrotoxicity of Tripterygium Tablet Extract and Triptolide in Monolayer HK 2 Cells Cultured in a Transwell Chamber

... renal tubular epithelial cells (RETCs) are damaged, some kidney-specific or non-specific substances in the cells are ...of proximal tubules [17] [18] [19], GGT activity in the super- ...

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Different sulfonylureas induce the apoptosis of proximal tubular epithelial cell differently via closing KATP channel

Different sulfonylureas induce the apoptosis of proximal tubular epithelial cell differently via closing KATP channel

... of tubular epithelial cells, especially PTECs, play an important role in the progression of DKD (Wakino et ...beta cells due to sustained enhancement of Ca 2+ influx and stimulated production ...

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Induction of heparin binding epidermal growth factor like growth factor mRNA in rat kidney after acute injury

Induction of heparin binding epidermal growth factor like growth factor mRNA in rat kidney after acute injury

... in tubular epithelial ...rabbit proximal tubule cells and NRK 52E normal rat kidney epithelial cells, with potency similar to that of ...

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Targeting of a platinum-bound sunitinib analog to renal proximal tubular cells

Targeting of a platinum-bound sunitinib analog to renal proximal tubular cells

... the proximal tubular cell-specific internalizing megalin receptor (green color) at 10 minutes and 1, 4, and 24 hours after intravenous administration of a single dose of 20 mg/kg ...the tubular lumen ...

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Original Article Hepatorenal syndrome: insights into the mechanisms of intra-abdominal hypertension

Original Article Hepatorenal syndrome: insights into the mechanisms of intra-abdominal hypertension

... renal tubular epithelial cells and lumen were normal in both group of IAP= 0cmH 2 O (Figures 2A and ...renal tubular lumen and a few inflam- matory infiltration in the interstitial could be ...

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The role of toll-like receptors in multifactorial mechanisms of early and late renal allotransplant injury, with a focus on the TLR4 receptor and mononuclear cells

The role of toll-like receptors in multifactorial mechanisms of early and late renal allotransplant injury, with a focus on the TLR4 receptor and mononuclear cells

... RTE cells, endothelial cells and ...blood cells involved in adaptive immunity ...dendritic cells). By re- maining in a proportional numerical equilibrium with cells circulating in the  ...

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