Pyruvate kinase PK
In vitro studies on the effect of methanolic extract of Elytraria acaulis on the glucose metabolism of Cotylophoron cotylophorum
... by pyruvate kinase (PK) to pyruvate, which is further reduced to lactate by lactate dehydrogenase ...to pyruvate and part is reduced to succinate through ...
7
Alteration of parameters of energy metabolism and ATPase enzymatic system in juvenile common carp (Cyprinus carpio) chronically exposed to tributyltin
... Environmental contaminants inducing physi- ological regulations in organisms are being used as diagnostic tools in assessing potential biological impacts in aquatic systems (Brain and Cedergreen 2009; Li et al. 2011a, ...
7
Role of isoenzyme M2 of pyruvate kinase in urothelial tumorigenesis
... 12]. Pyruvate kinase (PK) is a key enzyme that catalyzes the final, rate-limiting step of glycolysis by transferring a phosphate group from phosphoenolpyruvate to ADP [13, ...muscle-type PK ...
14
Regulation of Metabolic Pathways PVY-RNA Biosynthesis in Tobacco: Glycolytic Pathway
... and pyruvate kinase (PK), were not influenced by PVY infection (data not shown; the statistical evaluation of paired t-test did not show any statistically significant difference between the healthy ...
6
Warburg effect hypothesis in autism Spectrum disorders
... into pyruvate is the final step in glycolysis after glucose entered the ...enzyme pyruvate kinase (PK) catalyzes this reaction. PK have four isoforms: PKM1, PKM2, PKL, and ...
7
Nutritional regulation and tissue specificity of gene expression for proteins involved in hepatic glucose metabolism in rainbow trout (Oncorhynchus mykiss)
... (6PF-2K/F-2,6BPase), pyruvate kinase (PK), fructose-1,6-bisphosphatase (FBPase) and glucose transporter type 2 (Glut2) gene expression in food- deprived rainbow trout and fed rainbow trout with 20 % ...
10
Molecular study of pyruvate kinase deficient patients with hereditary nonspherocytic hemolytic anemia
... DNA analysis was performed on 30 unrelated patients with hereditary nonspherocytic hemolytic anemia (HNSHA) who had been found to be pyruvate kinase (PK) deficient by enzyme assay. 19 different ...
9
EFFECT OF ETHANOL EXTRACT OF TRACHYSPERMUM AMMI ON PYRUVATE KINASE AND PHOSPHOENOLPYRUVATE CARBOXYKINASE OF COTYLOPHORON COTYLOPHORUM
... phosphoenol pyruvate (PEP) is a branch point which is either converted to pyruvate by pyruvate kinase (PK) or to oxaloacetate by phosphoenolpyruvate carboxy kinase (PEPCK) ...
8
Molecular Response of Carbohydrate Metabolism to Dietary Carbohydrate and Acute Low Salinity Stress in Pacific White Shrimp Litopenaeus vannamei
... Dietary polysaccharide can be hydrolyzed to oligosaccharides, branched chain α-dextrin or maltose in the digestive gland of crustaceans (van Wormhoudt and Favrel, 1988), and then is completely hydrolyzed to ...
17
Nonmetabolic functions of metabolic enzymes in cancer development
... protein kinase activity to phosphorylate protein ...activate pyruvate dehydrogenase kinase isozyme 1 (PDHK1) at ...of pyruvate dehydrogenase E1α at Ser293 inhibits the pyruvate ...
7
The role of pyruvate kinase in the regulation of glycolysis and gluconeogenesis in Propionibacterium shermanii : a thesis presented in partial fulfilment of the requirements for the degree of Doctor of Philosophy in Biochemistry at Massey University, New Zealand
... of pyruvate kinase by G6P may a lso serve to determine the rel ative fl ux via the PEP: carboxytransphosphoryl ase and pyruvate kinase enzymes - the carboxytransphosphoryl ase functioning to ...
18
Probing Conformational Feature of a Recombinant Pyruvate Kinase by Limited Proteolysis
... of PK generated minimal peptide cleavage, and even after 6 h no difference in proteolysis pattern was observed for treated protein under thermal conditions ...
9
Pyruvate kinase M2 is requisite for Th1 and Th17 differentiation
... activates pyruvate kinase ...type). Pyruvate kinase is at the final step of glycolysis and converts phosphoenolpyruvate to ...of pyruvate kinase (Supplemental Figure ...
14
Pyruvate Dehydrogenase Complex Activity in Normal and Deficient Fibroblasts
... Pyruvate dehydrogenase complex (PDC) activity in human skin fibroblasts appears to be regulated by a phosphorylation-dephosphorylation mechanism, as is the case with other animal cells. The enzyme can be activated ...
10
Physiological and molecular characterizations of the interactions in two cellulose-to-methane cocultures
... For VFA biosynthesis, the gene (Clocel 1892) encoding ace- tate kinase for catalyzing pyruvate to acetate was upregu- lated, whereas the gene (Clocel 3674) encoding butyrate kinase wit[r] ...
14
Evaluation of tumor M2 pyruvate kinase (Tumor M2 PK) as a biomarker for pancreatic cancer
... This study has re-evaluated plasma Tumor M2-PK as a potential marker of prognosis in patients with pancreatic and peri-ampullary cancer. As the dimeric M2 isoform detected by the assay is overexpressed in cancer, ...
6
Prevalence of Pyruvate Kinase Deficiency among the Newborns (Shiraz-Iran)
... Phosphoglycerate kinase which are X-linked, the other 12 hereditary erythrocyte enzyme abnormalities that result in heridatery non-spherocytic hemolytic anemia (HNSHA) have autosomal recessive (AR) ...to PK ...
5
Cysteine catabolism and the serine biosynthesis pathway support pyruvate production during pyruvate kinase knockdown in pancreatic cancer cells
... through PK, indicating that PK is the rate-limiting step in glycolysis during PKM knock- ...down. Pyruvate levels were unchanged, but downstream intermediate lactate was significantly decreased with ...
13
The regulation of some glycolytic enzymes in streptococcus lactis : a thesis presented in partial fulfilment of the requirements for the degree of Doctor of Philosophy in Biochemistry at Massey University, New Zealand
... reversibly interconverted by sulphydryl reagent s as had be en shown for the L-type pyruvate kinase from rat liver (Van Berkel � �. , 1 973a ) . They showed that M�type enzyme if incubated overnight with ...
271
Cadmium induces both pyruvate kinase and Na+/H+ exchanger activity through protein kinase C mediated signal transduction, in isolated digestive gland cells of Mytilus galloprovincialis (L )
... for PK activity were also observed after treatment with isoprenaline (results not ...in PK activity and on pHi after co-exposure to cadmium together with various agonists or PMA was synergistic (Tables 3, ...
10