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rat C6 glioma cells

Sensitization of rat C6 glioma cells to ionizing radiation by porphyrins

Sensitization of rat C6 glioma cells to ionizing radiation by porphyrins

... tize cells and tumours to ionizing ...malian cells and tumours to ionizing radiation (18, ...malignant glioma cells exposed to ionizing radiation (2–6 ...a rat glioma tumour ...

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Mechanisms of tumor necrosis factor-α-induced interleukin-6 synthesis in glioma cells

Mechanisms of tumor necrosis factor-α-induced interleukin-6 synthesis in glioma cells

... TNF-a-induced IL-6 release is dependent on the IB- NFB pathway [4]. Several sites in the N-terminal Rel homology domain, including Ser 276, or in the C termi- nus transactivation domain region play a pivotal role in the ...

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Modulation of inducible nitric oxide synthase expression by sumoylation

Modulation of inducible nitric oxide synthase expression by sumoylation

... In rat C6 glioma cells, NOS2 induction by over-expression of MAPKs was blocked by a dominant negative form of C/EBPβ ...muscle cells induction of NOS2 was accompanied by binding of ...

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The role of thrombin in gliomas

The role of thrombin in gliomas

... a C6 glioma ...reduce glioma mass and neurologic deficits and extend survival time in C6 and F98 ...and rat C6 glioma cells (in vitro and in vivo) was assessed using ...

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Neonatal dexamethasone treatment exacerbates hypoxic-ischemic brain injury

Neonatal dexamethasone treatment exacerbates hypoxic-ischemic brain injury

... used rat primary cortical astrocytes and examined the extent of GLT-1 induction 72 hours after DEX (100 nM) treatment, whereas the present study examined the expression of GLT-1 in rat C6 ...

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Magnetic resonance imaging of glioma with novel APTS coated superparamagnetic iron oxide nanoparticles

Magnetic resonance imaging of glioma with novel APTS coated superparamagnetic iron oxide nanoparticles

... Belgium). C6 glioma cells (a rat C6 glioma cell line) were purchased from the Institute of Biochemistry and Cell Biology at the Chinese Academy of Sciences (Shanghai, ...

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Photodynamic Characterization and In Vitro Application of Methylene Blue containing Nanoparticle Platforms ¶

Photodynamic Characterization and In Vitro Application of Methylene Blue containing Nanoparticle Platforms ¶

... Confocal images calcein [green] and PI [red] channels are both shown of rat C6 glioma tumor cells treated with 1 mg/mL MB-loaded polyacrylamide nanoparticles: A before light exposure, ta[r] ...

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Inhibitory effects of lapachol on rat C6 glioma in vitro and in vivo by targeting DNA topoisomerase I and topoisomerase II

Inhibitory effects of lapachol on rat C6 glioma in vitro and in vivo by targeting DNA topoisomerase I and topoisomerase II

... tumor cells and several mouse models ...on glioma cells ...malignant glioma both in vitro and in ...on C6 cells in a dose dependent manner, with the IC ...

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Polymer Delivery of Hydroxycamptothecin against C6 Glioma

Polymer Delivery of Hydroxycamptothecin against C6 Glioma

... for C6 cells tested in ...with C6 glioma and treated with hydroxycamptothecin polymer compared to intravenous as well as intratumoral injections; the median survival is ...a rat ...

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Targeted therapy for glioma using cyclic RGD-entrapped polyionic complex nanomicelles

Targeted therapy for glioma using cyclic RGD-entrapped polyionic complex nanomicelles

... inhibit glioma cells in vivo, Wistar rats were implanted with the C6 glioma cell line and treated with c(RGDfC) polyionic complex micelles or ...the rat brain (Figure 5A) indicated ...

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Midazolam suppresses interleukin-1β-induced interleukin-6 release from rat glial cells

Midazolam suppresses interleukin-1β-induced interleukin-6 release from rat glial cells

... In the physiological CNS, IL-1 b , a pro-inflammatory cytokine, is expressed at low levels [11-13]. IL-1 plays a role in some physiological processes including sleep and synaptic plasticity [12]. Levels of IL-1 b ...

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The effect of intranasally administered TLR3 agonist larifan on metabolic profile of microglial cells in rat with C6 glioma

The effect of intranasally administered TLR3 agonist larifan on metabolic profile of microglial cells in rat with C6 glioma

... affect C6 glioma cell ...of C6 gilioma cells isolated from tumor tissue as well as by the investigation of phenotypic profile of GAM at different time points within the course of ...of ...

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CALCIUM MODULATORY EFFECTS OF CROCIN FROM SAFFRON (CROCUS SATIVUS L.) IN C6 GLIOMACELLS

CALCIUM MODULATORY EFFECTS OF CROCIN FROM SAFFRON (CROCUS SATIVUS L.) IN C6 GLIOMACELLS

... Hepes). Cells were then incubated at 37°C in the above buffer with 5 μM fura-2 AM for 30 min in ...the cells were washed three times with the same buffer solution but without fura-2 AM at ...signal, ...

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Effects of quercetin nanoliposomes on C6 glioma cells through induction of type III programmed cell death

Effects of quercetin nanoliposomes on C6 glioma cells through induction of type III programmed cell death

... QUE-NL can induce cell death which may not involve apoptosis. Therefore, we investigated the induction of cell death in C6 glioma cells after exposure to QUE-NL. The results of this study indicate ...

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Synthesis and characterization of Agiopep-2 anchored PEGylated poly propyleneimine dendrimers for targeted drug delivery to glioblastoma multiforme

Synthesis and characterization of Agiopep-2 anchored PEGylated poly propyleneimine dendrimers for targeted drug delivery to glioblastoma multiforme

... The present study was aimed at developing and exploring the use of Angiopep-2 anchored PEGylated Poly propyleneimine (PPI) dendrimers for targeted delivery of paclitaxel to the brain glioma. PPI dendrimers were ...

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Statin-induced apoptosis via the suppression of ERK1/2 and Akt activation by inhibition of the geranylgeranyl-pyrophosphate biosynthesis in glioblastoma

Statin-induced apoptosis via the suppression of ERK1/2 and Akt activation by inhibition of the geranylgeranyl-pyrophosphate biosynthesis in glioblastoma

... In the present study, we have demonstrated that statins inhibit C6 glioma cell proliferation. We have also found that statins induce apoptosis by activation of caspase-3 through inhibition of GGPP ...

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Arsenic trioxide inhibits glioma cell growth through induction of telomerase displacement and telomere dysfunction

Arsenic trioxide inhibits glioma cell growth through induction of telomerase displacement and telomere dysfunction

... apoptosis-promoting protein, was induced by p53, which is additional evidence of p53-dependent apoptosis [44]. Cell cycle arrest is another result of DNA damage [45]. ATM and ATR are major signals of G2-M phase arrest ...

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The regulation of tissue plasminogen activator in rat brain glioma cells

The regulation of tissue plasminogen activator in rat brain glioma cells

... ing cells. T he cells w ere scraped into PBS using a "silicon" rubber policem en and spun at 3500 rpm for 4 m ins in a Sorval SS45 ...The cells w ere resuspended again and the 50% sucrose ...

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Cytotoxicity induced by carbon nanotubes in experimental malignant glioma

Cytotoxicity induced by carbon nanotubes in experimental malignant glioma

... into cells. Immediately thereafter, RG2 cells were incubated in the absence (control) or presence of the different CNTs alone or combined with TMZ at 37 ° C for 1 h when ROS levels were detected at the ...

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Reactive oxygen intermediates increase vascular endothelial growth factor expression in vitro and in vivo

Reactive oxygen intermediates increase vascular endothelial growth factor expression in vitro and in vivo

... and rat (27) diabetic eyes, and in eyes with retinopathy of prematurity ...inflammatory cells (33) may be re- sponsible for the high ROI levels that are present in some tu- mors (34, ...

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