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Rat Microvascular Endothelial Cells

Original Article Effect of caveolin-1 on the expression of tight junction-associated proteins in rat glioma-derived microvascular endothelial cells

Original Article Effect of caveolin-1 on the expression of tight junction-associated proteins in rat glioma-derived microvascular endothelial cells

... in rat cryogenic brain injury model, and the expression of tight junction proteins (occludin and claudin-5) were downregulated when caveolin-1 level increased; Zhong et ...

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A Novel Brain Neurovascular Unit Model with Neurons, Astrocytes and Microvascular Endothelial Cells of Rat

A Novel Brain Neurovascular Unit Model with Neurons, Astrocytes and Microvascular Endothelial Cells of Rat

... brain microvascular endothelial cells (BMECs) and astrocytes was established in this study for investigating the cerebral diseases and screening the candidates of therapeutic ...brain cells ...

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Original Article Hemodynamic study about laminar shear stress extenuate cerebral ischaemia-reperfusion injury

Original Article Hemodynamic study about laminar shear stress extenuate cerebral ischaemia-reperfusion injury

... Abstract: Objective: In this study, we explored whether laminar shear stress (LS) had an effect on the apoptosis of rat brain microvascular endothelial cells (rBMECs) during the course of ...

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Binding of diamine oxidase activity to rat and guinea pig microvascular endothelial cells  Comparisons with lipoprotein lipase binding

Binding of diamine oxidase activity to rat and guinea pig microvascular endothelial cells Comparisons with lipoprotein lipase binding

... the endothelial cell surface did not interfere with the binding of DAO activity except when cells were exposed to high concentrations of ...of cells with proteolytic and glycosaminoglycandegrading ...

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Purine Transport and Metabolism in Microvascular Endothelial Cells

Purine Transport and Metabolism in Microvascular Endothelial Cells

... than rat MVECs with respect to their nucleoside and nucleobase transport ...However, rat MVECs appear to have less of the dipyridamole-insensitive [ 3 H]hypoxanthine transporter and instead use ENT2 as the ...

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Flavin Containing Monooxygenase (FMO) Protein Expression and Its Activity in Rat Brain Microvascular Endothelial Cells

Flavin Containing Monooxygenase (FMO) Protein Expression and Its Activity in Rat Brain Microvascular Endothelial Cells

... tured rat brain microvascular endothelial cells (BMECs), which constitute the blood-brain barrier (BBB), and whether N-oxide from the tertiary amine, d-chlorpheniramine, was formed by FMO in ...

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Amplification of P. falciparum Cytoadherence through Induction of a Pro-Adhesive State in Host Endothelium.

Amplification of P. falciparum Cytoadherence through Induction of a Pro-Adhesive State in Host Endothelium.

... of endothelial cells and the required direct physical contact can be as little as 30 to 60 minutes ...multiple endothelial cell types and parasite lines to verify the hypothesis that increased ...

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PubMedCentral-PMC4732907.pdf

PubMedCentral-PMC4732907.pdf

... in endothelial cells, we first crossed LRP1 flox/flox (LRP1 f/f ) mice with Tie2Cre + transgenic mice to generate LRP1 f/f ;Tie2Cre +/− ...in endothelial cells (Figure 1A) as well as ...

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ENT1 and ENT1 mice during both normoxic and hypoxic conditions. Gene expression was

ENT1 and ENT1 mice during both normoxic and hypoxic conditions. Gene expression was

... Another hypoxia induced factor is nitric oxide (NO) which is the active moiety of the endothelium-derived relaxing factor (EDRF) [40]. As a key regulator of vascular homeostasis, under basal conditions, low levels of NO ...

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HIV 1 associated dementia: symptoms and causes

HIV 1 associated dementia: symptoms and causes

... can have neuro-protective effects [49,87]. The role of CXCR4 in the gp120 mediated neurotoxicity can be direct, through the activation of neuronal receptors by gp120, or indirect through the stimulation of glial ...

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Palmitate-Induced Apoptosis of Microvascular Endothelial Cells and Pericytes

Palmitate-Induced Apoptosis of Microvascular Endothelial Cells and Pericytes

... Background: Recent observations in the EURODIAB Complications Study demonstrated that markers of in- sulin resistance are strong risk factors for retinopathy inci- dence in patients with diabetes. However, the molecular ...

6

ATF4 is a novel regulator of MCP-1 in microvascular endothelial cells

ATF4 is a novel regulator of MCP-1 in microvascular endothelial cells

... lial cells, which in turn promotes monocyte/macrophage adhesion and migration into retinal tissue resulting in in- ...brain endothelial cells were transduced with Ad-ATF4 or treated with 250 ng/ml of ...

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Lipopolysaccharide-enhanced transcellular transport of HIV-1 across the blood-brain barrier is mediated by luminal microvessel IL-6 and GM-CSF

Lipopolysaccharide-enhanced transcellular transport of HIV-1 across the blood-brain barrier is mediated by luminal microvessel IL-6 and GM-CSF

... Elevated levels of cytokines/chemokines contribute to increased neuroinvasion of human immunodeficiency virus type 1 (HIV-1). Previous work showed that lipopolysaccharide (LPS), which is present in the plasma of patients ...

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adrenoceptor protects human pulmonary microvascular endothelial cells from TNF-α induced hyper-permeability

adrenoceptor protects human pulmonary microvascular endothelial cells from TNF-α induced hyper-permeability

... HPMECs were seeded into 96-well plates and grown to 80-90% confluence, then subject to different treatments. 12 h later, cell monolay- ers were washed, fixed for 15 min in 2% para- formaldehyde and blocked with 2% normal ...

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Cyclosporin A differentially inhibits multiple steps in VEGF induced angiogenesis in human microvascular endothelial cells through altered intracellular signaling

Cyclosporin A differentially inhibits multiple steps in VEGF induced angiogenesis in human microvascular endothelial cells through altered intracellular signaling

... ascular endothelial cells, inhibiting all of the stages of in vitro angiogenesis which were ...migration, endothelial monolayer expansion and proliferation, and tube ...to microvascular ...

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The roles of neutrophil serine proteinases in idiopathic inflammatory myopathies

The roles of neutrophil serine proteinases in idiopathic inflammatory myopathies

... the endothelial cell, disturb the endothelial cytoskeletal archi- tecture, increase endothelial cell apoptosis, and reduce viability [17, ...from endothelial cells [48], to activate ...

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The role and regulation of VEGF-mediated ERK5 activity in endothelial cells

The role and regulation of VEGF-mediated ERK5 activity in endothelial cells

... Endothelial cells display a significant amount of heterogeneity across the vascular tree; the most apparent difference being their morphology (Aird, ...Typically, endothelial cell are flat in ...

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Transendothelial migration of human umbilical mesenchymal stem cells across uterine endothelial monolayers: junctional dynamics and putative mechanisms

Transendothelial migration of human umbilical mesenchymal stem cells across uterine endothelial monolayers: junctional dynamics and putative mechanisms

... Abbreviations: Mesenchymal stem cells MSC from Wharton’s jelly of human umbilical cords WJ-MSC, human uterine microvascular endothelial cells HUtMEC, vascular endothelial cadherin VE-cad[r] ...

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Intercellular adhesion molecule 1 and CD36 synergize to mediate adherence of Plasmodium falciparum infected erythrocytes to cultured human microvascular endothelial cells

Intercellular adhesion molecule 1 and CD36 synergize to mediate adherence of Plasmodium falciparum infected erythrocytes to cultured human microvascular endothelial cells

... lar endothelial cells (HDMEC) and human umbilical vein endothelial cells (HUVEC) and have assessed the relative roles of the receptors CD36 and intercellular adhesion mol- ecule-1 ...infected ...

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Air pollutant chemicals and oxidized lipids exhibit genome wide synergistic effects on endothelial cells

Air pollutant chemicals and oxidized lipids exhibit genome wide synergistic effects on endothelial cells

... of endothelial cells, we have previously reported in macrophages and bronchial epi- thelial cells that in vitro DEP extract concentrations in the dose range 1-100 mg/ml correspond to realistic ...

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