Receptors, Dopamine D2
Effects of 17β Estradiol on Dopamine D2 Receptors in Thiamine Deficient Female Rats: Consequences on Sucrose, Alcohol, Water Intakes and Body Weight
... modulated dopamine D2 receptor in regulating body weight ...on dopamine D2 receptors, using bromocriptine mesylate (BR) and sulpiride (SUL) as selective central ...
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Effects of Ovariectomy and 17β Estradiol Replacement on Dopamine D2 Receptors in Female Rats: Consequences on Sucrose, Alcohol, Water Intakes and Body Weight
... dysregulating dopamine D2 receptors, thereby inducing food addiction, glucose craving or alcohol dependence through reward ...and dopamine D2 receptors interferences in the ...
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Agonist signalling properties of radiotracers used for imaging of dopamine D2/3 receptors
... beta-arrestin-biased dopamine D2 ligands for probing signal transduction pathways essential for antipsychotic ...of dopamine D2/3 receptors in their high-affinity ...
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Corticosterone and dopamine D2/D3 receptors mediate the motivation for voluntary wheel running in C57BL/6J mice
... dopaminergic D2/D3 receptors also had limited impact on behavioural ...of dopamine D2/D3 receptors contributed to the motivation for exercise but the level of engagement in wheel ...
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Dopamine D2 receptors in the pathophysiology of insulin resistance
... Allereerst wil ik mijn promotor bedanken. Hanno, dank je wel voor je begeleiding en voor het vertrouwen dat je in mij had, zeker toen bleek dat mijn originele project niet het gewenste resultaat had en het roer omgegooid ...
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D amphetamine and antipsychotic drug effects on latent inhibition in mice lacking dopamine D2 receptors
... glutamate receptors, has also been implicated in schizophrenia (Olney et al, ...NMDA receptors are regulated by the amino-acid glycine and drugs that interact with transporters for glycine (GlyT1) may have ...
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Role of dopamine D2 receptors in ischemia/reperfusion induced apoptosis of cultured neonatal rat cardiomyocytes
... death receptors of the tumor necrosis factor receptor superfamily (Fas and TNF receptor) results in activation of the initiator cas- pase-8, which can propagate the apoptosis signal by direct cleavage of ...
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Sinomenine activates astrocytic dopamine D2 receptors and alleviates neuroinflammatory injury via the CRYAB/STAT3 pathway after ischemic stroke in mice
... astrocytic dopamine D2 receptor (DRD2) suppressed neuroinflammation in intracerebral hemorrhage and 1- methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-in- duced neurotoxicity [14, ...
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Cytoplasm-predominant Pten associates with increased region-specific brain tyrosine hydroxylase and dopamine D2 receptors in mouse model with autistic traits
... much dopamine in the prefrontal cortex and midbrain, which can result in repetitive and obsessive ...dysregulated dopamine function in ASD ...the dopamine transporter gene, caused alterations in ...
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Modulatory Effects of Dopamine D2 Receptors on Spreading Depression in Rat Somatosensory Neocortex
... is dopamine receptor hypersensitivity in patients with migraine (Gorji, ...patients, dopamine acts as an endogenous protagonist in the pathophysiology of mi- ...
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Extrapyramidal side effects of antipsychotics are linked to their association kinetics at dopamine D2 receptors
... However, support for this hypothesis is limited to a relatively small number of observations made across several decades and under different experimental conditions. Here we show that association rates, but not ...
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Co-Administration of Curcumin and Bromocriptine Nano-liposomes for Induction of Apoptosis in Lung Cancer Cells
... the dopamine D2 receptors on pituitary epithelial cells to prevent prolactin ...stimulates dopamine receptors and has anti-mitotic and anti-tumor ...properties. D2 receptor mRNA ...
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Epigenetic variance in dopamine D2 receptor: a marker of IQ malleability?
... in dopamine metabolism and neurotransmission: tyrosine hydroxylase (TH); DOPA decarboxylase (DDC); catechol-O-methyl transferase (COMT); dopamine transporter 1 (SLC6A3); dopamine receptor D1 (DRD1); ...
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Knocking Down the DRD2 by shRNA Expressing Plasmids in the Nucleus Accumbens Prevented the Disrupting Effect of Apomorphine on Prepulse Inhibition in Rat
... dopaminergic receptors involved in PPI impairment by dopamine agonists is not ...against dopamine D2 receptor genes (DRD2) in the nucleus accumbens, here, we studied the effect of apomorphine ...
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Endoscopic Evaluation of Gastric Emptying and Effect of Mosapride Citrate on Gastric Emptying
... Mosapride, a substituted benzamide, is a 5-HT4 receptor agonist.14-16 This drug does not antagonize dopamine D2 receptors, but selectively acts on 5-HT4 receptors, thus enhancing gastroi[r] ...
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BIOCHEMICAL, NEUROCHEMICAL AND BEHAVIOURAL RESPONSES FOLLOWING ADMINISTRATION OF 6-FLUORO-3-(PIPERIDIN-4-YL) BENZO[D] ISOXAZOLE DERIVATIVES AND ANTIPSYCHOTIC DRUGS IN MICE
... with dopamine D2 receptor with lesser affinity and serotonin 5HT2a receptors with comparably higher affinity as possible drug molecules with fewer propensities to cause ...
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Synthesis and evaluation in rats of homologous series of [18F]-labeled dopamine D2/3 receptor agonists based on the 2-aminomethylchroman scaffold as potential PET tracers
... 23. Mewshaw RE, Kavanagh J, Stack G, Marquis KL, Shi X, Kagan MZ, et al. New generation dopaminergic agents. 1. Discovery of a novel scaffold which embraces the D2 agonist pharmacophore. Structure-activity ...
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Thesis
... a D2-selective drug, and dopamine, the endogenous D2R ligand (Figure ...the dopamine D2 receptor (Montmayeur, Guiramand, & Borrelli, 1993), we predicted that quinpirole and dopamine ...
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RECENT CONCEPTS IN CLINICAL PSYCHIATRY: DRUG TREATMENT IN SCHIZOPHRENIA
... of receptors specially 52, -1 adrenergic, Hi receptors. Dl and D2 receptors are effected to a lessor ...in D2 receptor number or affinity but like sulpride it may increase Di ...
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Development of a peptide targeting dopamine transporter to improve ADHD-like deficits
... striatal dopamine transporter activity, which is reverted by the administration of methylphenidate [59, ...of dopamine dysregulation and dopamine transporter in ADHD, we are curious about whether the ...
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