recombination hotspot
A 160-bp Palindrome Is a Rad50·Rad32-Dependent Mitotic Recombination Hotspot in Schizosaccharomyces pombe
... totic recombination hotspots in ...L-pal-dependent recombination hotspot activity Instability of such structures can be deleterious, as ob- in ...
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A Family of cAMP-Response-Element-Related DNA Sequences With Meiotic Recombination Hotspot Activity in Schizosaccharomyces pombe
... meiotic recombination hotspot in the ade6 gene of Schizosaccharomyces ...pombe. Hotspot activity is associated with binding of the heterodimeric transcription factor Atf1·Pcr1 to ...and ...
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Properties of Natural Double-Strand-Break Sites at a Recombination Hotspot in Saccharomyces cerevisiae
... of recombination hotspots in Saccharomyces cerevisiae : How much DNA is required for double-strand-break (DSB) site recognition? Do naturally oc- curring DSB sites compete with each other in meiotic ...
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Fission Yeast Tup1-Like Repressors Repress Chromatin Remodeling at the fbp1+ Promoter and the ade6-M26 Recombination Hotspot
... and recombination, are finely regulated by chro- element (CRE)-like sequences, including one in the matin ...cific recombination hotspot ade6-M26 locus ...
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Optimizing the Nucleotide Sequence of a Meiotic Recombination Hotspot in Schizosaccharomyces pombe
... for hotspot activity; the Atf1-Pcr1 transcription factor binds to this sequence and activates ...a hotspot, we used an in vitro selection method (SELEX) that revealed an 18-bp consensus sequence for ...
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Fine-Structure Mapping of Meiosis-Specific Double-Strand DNA Breaks at a Recombination Hotspot Associated With an Insertion of Telomeric Sequences Upstream of the HIS4 Locus in Yeast
... The number in parentheses represents the position of the 5' base of the oligonucleotide within the BgRI fragment containing the BZKl and HIS4 gene, with + 1 repre- senting[r] ...
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Counteracting Regulation of Chromatin Remodeling at a Fission Yeast cAMP Responsive Element-Related Recombination Hotspot by Stress-Activated Protein Kinase, cAMP-Dependent Kinase and Meiosis Regulators
... Figure 1.—The PKA pathway negatively regu- lates M26 chromatin re- modeling. (A) DNA se- quences of ade6 ⫹ , ade6- M375 (negative control), and ade6-M26 (recombina- tion hotspot) alleles. White letters indicate G ...
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Self-Inflicted Wounds, Template-Directed Gap Repair and a Recombination Hotspot: Effects of the mariner Transposase
... Transposase-induced hotspot of recombination: To ...tional hotspot in the presence of transposase, we carried 39 end of peach, and 29 had either an excision of peach out the experiments reported in ...
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Chromatin-mediated regulators of meiotic recombination revealed by proteomics of a recombination hotspot
... the hotspot [17, 20] and whose acetyltransferase (Mst2) contributes to hotspot activation ...additional, hotspot-enriched, individual and combinatorial PTM marks on histones are potential activators, ...
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Requirements for activity of the yeast mitotic recombination hotspot HOT1: RNA polymerase I and multiple cis-acting sequences.
... HOTl is derived from the rDNA repeat unit, and the sequences required for the recombination-stimulatory activity closely correspond to the rDNA transcription enhance[r] ...
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Affinity-seq detects genome-wide PRDM9 binding sites and reveals the impact of prior chromatin modifications on mammalian recombination hotspot usage
... in hotspot usage in non-PRDM9 organisms came with findings that hotspots in the bud- ding yeast ...yeast recombination hotspots are marked by H3K4me3, and loss of the H3K4 methyltrans- ferase SET1 results ...
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Genetic evidence that the meiotic recombination hotspot at the HIS4 locus of Saccharomyces cerevisiae does not represent a site for a symmetrically processed double-strand break.
... Patterns of co-PMS and other co-events at the HIS4 and BZKl loci: Although the comparison of aberrant segregation frequencies of SPY200 (wild- type Rapl-binding s[r] ...
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Genetic and physical analysis of the M26 recombination hotspot of Schizosaccharomyces pombe.
... Meiosis-specific action of ade6-MZ6: To deter- mine whether ade6-M26 stimulates mitotic as well as meiotic recombination, we constructed strains to test the mitotic and [r] ...
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Active and inactive transplacement of the M26 recombination hotspot in Schizosaccharomyces pombe.
... We considered two technical explanations for the lack of M26 hotspot activity in the plasmid X chromo- some recombination assays: the multicopy plasmid con- taining the M[r] ...
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Genetic analysis of a meiotic recombination hotspot on chromosome III of Saccharomyces cerevisiae.
... One simple explanation of these results is that the same number of crossover events (and associated con- version events) are initiated in LS81 and the control strains, but re[r] ...
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Analysis of a recombination hotspot for gene conversion occurring at the HIS2 gene of Saccharomyces cerevisiae.
... Analysis of the conversion frequency in diploids con- taining homozygous insertions located downstream of HIS2 confirmed that sequences necessary for the high frequency of gen[r] ...
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Nonrandom distribution of chloroplast recombination events in Chlamydomonas reinhardtii: evidence for a hotspot and an adjacent cold region.
... Functional analysis of the recombination hotspot during biolistic transformation of the PsbA gene: T o analyze the hotspot in greater detail and develop a system to loc[r] ...
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Alleles of the Hotspot cog Are Codominant in Effect on Recombination in the his-3 Region of Neurospora
... the recombination hotspot cog, which is located ...creases recombination in the his-3 region compared to a cross homozygous for the cog ...suggests recombination mechanisms may differ in ...
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Hotspot swells and the lifespan of volcanic ocean islands
... each hotspot to predicted thermal subsidence of reheated lith- ...each hotspot swell using measurements of swell length and plate velocity in the hotspot reference ...
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Query Hotspot Decomposition and Load Balancing
... as many messages as the number of its direct neighbors. No maintenance messages are further sent during the simulation. Query hotspots are generated as follows. At the start of each simulation, a small amount of ...
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