recurrent Clostridium difficile infection
Complete Microbiota Engraftment Is Not Essential for Recovery from Recurrent Clostridium difficile Infection following Fecal Microbiota Transplantation
... for recurrent Clostridium difficile infection (rCDI) by fecal microbiota transplantation (FMT), using either heterologous donor stool samples or autologous stool samples, were characterized by ...
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Risk factors for recurrent Clostridium difficile infection (CDI) hospitalization among hospitalized patients with an initial CDI episode: a retrospective cohort study
... It is worth noting that the recurrence rate we observed in the current study is at the lower end of what has been reported previously. For example, a recent meta-analysis by Garey et al. examined the literature on risk ...
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Effectiveness of fecal derived microbiota transfer using orally administered capsules for recurrent Clostridium difficile infection
... with Clostridium diffi- cile-associated disease had increases in Firmicutes, Proteo- bacteria and Actinobacteria with decreases in Bacteroidetes and in overall diversity of the gut microbiome ...
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Coinfection and Emergence of Rifamycin Resistance during a Recurrent Clostridium difficile Infection
... vol). After 24 h the wells were checked for turbidity. Overnight cultures were then diluted 10-fold with sterile PCR-grade water into a fresh 96-well plate, sealed with film, and stored at ⫺ 20°C until required. One drop ...
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Long-term effects on luminal and mucosal microbiota and commonly acquired taxa in faecal microbiota transplantation for recurrent Clostridium difficile infection
... of Clostridium cluster IX, Proteobacteria, Bacilli and uncultured Clostridiales, which were reduced post- FMT, whereas Bacteroidetes were increased after treat- ment (all, P < ...to Clostridium cluster ...
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Laboratory Testing of Donors and Stool Samples for Fecal Microbiota Transplantation for Recurrent Clostridium difficile Infection
... T he intestinal microbiota is composed of a diverse array of microorganisms that play a vital role in metabolism, immune function, and gut homeostasis (1, 2). Dysbiosis, or abnormal alterations in intestinal microbiotal ...
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Microbiome alterations following solid-organ transplantation: consequences, solutions, and prevention
... C. difficile infection did not recur, the microbiome demonstrated dynamic changes that may in part have been related to the use of mycophenolate ...for recurrent Clostridium difficile ...
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Microbiologic factors affecting Clostridium difficile recurrence
... Relapse versus reinfection: recurrent Clostridium difficile infection following treatment with fidaxomicin or vancomycin.. Richardson C, Kim P, Lee C, Bersenas A, Weese JS.[r] ...
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Fecal microbiota transplantation for refractory diarrhea in immunocompromised diseases: a pediatric case report
... Diarrhea is the most common symptom in immuno- compromised (IC) children. Prophylactic, prolonged, and repeated antimicrobial use and an IC status caus- ing intestinal flora disorders can contribute to an in- creased ...
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Dynamics of the fecal microbiome in patients with recurrent and nonrecurrent Clostridium difficile infection
... Surprisingly, we also observed significant differences in microbial diversity between samples collected during severe disease or not. Although LEfSe analysis revealed seven differentially present OTUs between severe and ...
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Bezlotoxumab for the prevention of <em>Clostridium difficile</em> infection: a review of current evidence and safety profile
... Abstract: Clostridium difficile infection (CDI) is a leading nosocomial disease estimated to cause nearly half a million cases in the United States ...annually. Recurrent CDI (rCDI) affects ...
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An Observational Cohort Study of Clostridium difficile Ribotype 027 and Recurrent Infection
... the recurrent episodes and thus could not determine if the recurrence involved the same strain, though that determination is beyond the scope of this study, which was focused on the risk of recurrence based on the ...
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Clostridium difficile infection health disparities by race among hospitalized adults in the United States, 2001 to 2010
... respect to primary care access, as well as in surgery, sep- sis, and pneumonia [5–8, 10–12, 26]. However, little re- search has focused on disparities associated with healthcare-associated infections [13]. Our study adds ...
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Cost of hospital management of Clostridium difficile infection in United States—a meta analysis and modelling study
... Our systematic review has some limitations. First, all in- cluded studies reported direct medical costs from hospital perspective, therefore indirect cost to patients and society and costs of additional care after ...
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Antibodies for Treatment of Clostridium difficile Infection
... and that neither the titer nor number of serum-positive patients universally increase after a spontaneous or drug-induced cure— something that has also been witnessed in animal models (20). It would also appear that high ...
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Bezlotoxumab: an emerging monoclonal antibody therapy for prevention of recurrent <em>Clostridium difficile </em>infection
... Abstract: Clostridium difficile infection (CDI) is the most common health care-acquired infection associated with high hospital ...subsequent recurrent CDI increases with prior episodes ...
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2019 update of the WSES guidelines for management of Clostridioides (Clostridium) difficile infection in surgical patients
... Exposure to gastric acid-suppressive medications, such as histamine-2 blockers and PPIs, may be a potential risk factor for development of CDI. Several studies have suggested the association between use of stomach ...
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Clostridium difficile cure with fecal microbiota transplantation in a child with Pompe disease: a case report
... species infection, is indicated for severe infections, even if they are the first occurrence ...second recurrent CDI [21, 22]. In children, 30% have recurrence of infection either from the same ...
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Microbiome Data Distinguish Patients with Clostridium difficile Infection and Non C difficile Associated Diarrhea from Healthy Controls
... (not recurrent CDI), and their stool sample was ...C. difficile using the ...C. difficile antigen glutamate dehydrogenase (GDH) and the C. difficile toxin proteins A and ...C. difficile ...
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The epidemiology of Clostridium difficile infection in Australia
... C. difficile spores or the time taken to re- vert to a non-colonized ...C. difficile in asymptomatic colonized ...C. difficile after 40, 70 and >90 days follow-up, respectively ...C. ...
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