regulatory T
Regulatory T cells induced by B cells: a novel subpopulation of regulatory T cells
... with T cells at the B-T border in the spleen after 4 h of oral administration of proteins ...+ regulatory T cells in vitro ...+ regulatory T cells via IL-10 and MHC class II [52, ...
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Role of CD8+ regulatory T cells in organ transplantation
... recent emergence of composite tissue transplantation, which is the treatment of choice for patients suffering from severe burns and trauma, presents new challenges and opportunities for long-term transplant survival ...
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Dissecting Emerging Aspects of Regulatory Circuitry in Man and Mice: Regulatory T Cell Biology
... Regulatory T cells (Treg), a component of adaptive immunity, are well known for their immunosuppressive roles and their ability to maintain the balance between the immunological and pathological ...of ...
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The Difference of Lymphocyte Subsets Including Regulatory T Cells in Umbilical Cord Blood between AGA Neonates and SGA Neonates
... the regulatory T cells in cord blood of ap- propriate for gestational age (AGA) neonates with those of small for gestational age (SGA) ...neonates. Regulatory T cells and lymphocyte subsets ...
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Natural Regulatory T Cells and Persistent Viral Infection
... Suppressor T cell is an old term, originally found in the 1970s literature (49, 50), but it was short-lived because ad- vances in molecular biology soon afterward proved that the gene locus, thought to be ...
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Memory regulatory T cells reside in human skin
... Regulatory T cells (Tregs), which are characterized by expression of the transcription factor Foxp3, are a dynamic and heterogeneous population of cells that control immune responses and prevent ...memory ...
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Subsets of regulatory T cells and their roles in allergy
... In recent years, it is recognized that acquired immunity is controlled by regulatory T cell (Treg). Since fundamental pathophysiological changes of allergy are mainly caused by hyperresponsiveness of immune ...
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Role of dendritic cells in the induction of regulatory T cells
... Cytotoxic T-lymphocyte antigen 4; Cox-2: Cyclooxygenase-2; DCs: Dendritic cells; DN: Double negative; GALT: Gut associated lymphoid tissue; HAA: 3-hydroxyanthranilate; HGF: Hepatocyte growth factor; HIV: Human ...
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Impact of IL-27 on regulatory T cell responses
... While regulatory T (Treg) cells are critical to limit inflammation, their role during toxoplasmosis is controversial because this infection results in a dramatic decrease in the total numbers of these cells ...
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Regulatory T cells: friend or foe in immunity to infection
... between regulatory and effector cells in different individuals, disease settings and experimental ...effector T cells ...and regulatory T cells controlled the efficiency of recall immune ...
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Upregulation of CD47 in Regulatory T Cells in Atopic Dermatitis
... Fig. 3. Increased expression of CD47 in Treg cells from AD mice. (A) FACS analysis of expression of CD47 in Treg cells from thymuses and spleens from normal and AD mice. The ΔMFI of CD47 was determined in Treg cells. The ...
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Nature of Regulatory T Cells in the Context of Allergic Disease
... of T helper (Th)1 cytokines to Th2 cytokines is increased following SIT, and functional regulatory T cells are ...and T cells is increased, as well as expression of transforming growth factor ...
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GARP: a surface molecule of regulatory T cells that is involved in the regulatory function and TGF-β releasing
... There are many molecules that define regulatory T cells (Tregs) phenotypically and functionally. Glycoprotein A repetitions predominant (GARP) is a transmembrane protein containing leucine rich repeats. ...
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Control of T Cell Responses, Tolerance and Autoimmunity by Regulatory T Cells: Current Concepts
... Regulatory T cells are triggered by specific antigens, (in most cases unknown), but the antigenic specificity of sup- pression is ...Adaptive regulatory T cells which are induced by ...naive ...
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The role of regulatory T cells in cancer immunology
... Abstract: Regulatory T cells (Treg) are generally considered to be significant contributors to tumor escape from the host immune system. Emerging evidence suggests, however, that in some human cancers, Treg ...
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Regulatory T cells in rheumatoid arthritis
... Regulatory T cells were first discovered in experimental animal models and were subsequently identified in ...of T cells was described that was capable of downregulating or suppressing the functions ...
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Influence of Dietary Components on Regulatory T Cells
... negative T-cell sig- naling via upregulation of cytotoxic T-lymphocyte-associated protein 4 ...both T-cell types were isolated from mice fed a DHA ...a T cell into a Treg capable of suppress- ...
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Signals Controlling Regulatory T Cell Differentiation and Homeostasis
... that T cells could mediate tolerance, in addition to immunity, to antigenic challenge (Gershon and Kondo, ...a T cell-mediated form of ...suppressor T cells proliferated and complex models describing ...
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Regulatory T cells and control of the germinal centre response
... In contrast to the finding that Foxp3 + Treg cells sup- press the GC response, Leon and colleagues demon- strated that Treg cells can promote GC responses [48]. Using influenza infection in a strain of mice where treat- ...
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Unravelling the Functions of Regulatory T Cells during Infection
... During early life, administration of Clostridium species, a gram positive bac- teria,in conventional mice provided resistance to colitis and systemic antibody responses signifying a novel therapeutic approach to ...
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