Respiratory Syndrome
Spread, Circulation, and Evolution of the Middle East Respiratory Syndrome Coronavirus
... East respiratory syndrome coronavirus (MERS-CoV) was first documented in the Kingdom of Saudi Ara- bia (KSA) in 2012 and, to date, has been identified in 180 cases with 43% ...infections. Respiratory ...
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Spread of Mutant Middle East Respiratory Syndrome Coronavirus with Reduced Affinity to Human CD26 during the South Korean Outbreak
... mission potential diminishing greatly in subsequent generations (13). It is thought that human adaptation of animal coronavirus might be achieved through sequential mutations that enhance the affinity of S protein to the ...
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Evaluating the potential impact of targeted vaccination strategies against severe acute respiratory syndrome coronavirus (SARS-CoV) and Middle East respiratory syndrome coronavirus (MERS-CoV) outbreaks in the healthcare setting
... Acute Respiratory Syndrome (SARS) and Middle East Respiratory Syndrome (MERS) are two coronaviruses with demonstrated potential to generate significant nosocomial ...
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Middle East Respiratory Syndrome Coronavirus Spike Protein Is Not Activated Directly by Cellular Furin during Viral Entry into Target Cells
... ABSTRACT Middle East respiratory syndrome coronavirus (MERS-CoV) utilizes host cellular proteases to enter cells. A previous report shows that furin, which is distrib- uted mainly in the Golgi apparatus and ...
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Further Evidence for Bats as the Evolutionary Source of Middle East Respiratory Syndrome Coronavirus
... I n 2012, Middle East respiratory syndrome (MERS) emerged in Saudi Arabia. Clusters of fatal pneumonia in adults were determined to be caused by a novel lineage C betacoronavirus (2c CoV), termed MERS-CoV ...
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Clinical management of respiratory syndrome in patients hospitalized for suspected Middle East respiratory syndrome coronavirus infection in the Paris area from 2013 to 2016
... East respiratory syndrome coronavirus (MERS- CoV) is a single-stranded positive-sense RNA virus firstly isolated in 2012 in the Kingdom of Saudi Arabia (KSA) ...
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Middle East Respiratory Syndrome Coronavirus Infection in Dromedary Camels in Saudi Arabia
... East respiratory syndrome (MERS) is proposed to be a zoonotic disease; however, the reservoir and mech- anism for transmission of the causative agent, the MERS coronavirus, are ...
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Developing a plant virus-based expression system for the expression of vaccines against Porcine Reproductive and Respiratory Syndrome Virus
... Immunogenicity study of plant-made oral subunit vaccine against porcine reproductive and respiratory syndrome virus (PRRSV). Porcine reproductive and respiratory syndrome[r] ...
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Middle East respiratory syndrome coronavirus infection: virus host cell interactions and implications on pathogenesis
... Middle-East Respiratory Syndrome coronavirus (MERS-CoV) was identified to cause severe respiratory infection in humans since ...Human respiratory epithelial cells are highly susceptible to ...
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Severe Acute Respiratory Syndrome Coronavirus Nonstructural Proteins 3, 4, and 6 Induce Double Membrane Vesicles
... acute respiratory syndrome, or SARS, emerged as a life- threatening disease of unknown origin in late 2002 in the Guangdong Province of southern ...Eastern respiratory syndrome coro- navirus ...
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<p>Estimation Of Direct Medical Costs Of Middle East Respiratory Syndrome Coronavirus Infection: A Single-Center Retrospective Chart Review Study</p>
... Acute Respiratory Syndrome coronavirus (SARS-CoV) outbreak resulted in an estimated global economic cost of $16 billion, 5 and it is believed that the MERS-CoV infection toll on the overall global economy, ...
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Absence of association between angiotensin converting enzyme polymorphism and development of adult respiratory distress syndrome in patients with severe acute respiratory syndrome: a case control study
... The outbreak of the severe acute respiratory syndrome (SARS) has made a great impact to the health care systems around the world. The pandemic affected over 8000 indi- viduals and resulted in 774 deaths ...
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Complement Activation Contributes to Severe Acute Respiratory Syndrome Coronavirus Pathogenesis
... acute respiratory syndrome coronavirus (SARS-CoV) emerged in 2002 and 2003 from coronaviruses circulating in animal markets in China ...of respiratory disease, with over 8,000 human cases and 10% ...
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ACE-1 I/D Polymorphism Associated with COVID-19 Incidence and Mortality: An Ecological Study
... 10. Chan KA, Tang NL, Hui DS, Chung GT, Wu AK, Chim SS, et al. Absence of association between angiotensin converting enzyme polymorphism and development of adult respiratory distress syndrome in patients ...
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Return_of_the_Coronavirus.pdf
... acute respiratory syndrome coronavirus (SARS-CoV) and Middle East respiratory syndrome coronavirus (MERS-CoV) infections, patients exhibited symptoms of viral pneumonia including fever, ...
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Revealing SARS-CoV-2 Functional Druggability Through Multi-Target Cadd Screening of Repurposable Drugs
... ABBREVIATIONS: COVID-19 (CoronaVirus Disease-2019); Severe Acute Respiratory Syndrome (SARS); Middle Eastern Respiratory Syndrome (MERS); computer-aided drug design (CA[r] ...
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Feasibility of Known RNA Polymerase Inhibitors as Anti-SARS-CoV-2 Drugs
... Acute Respiratory Syndrome Coronavirus (SARS-CoV), Middle East Respiratory Syndrome Coronavirus (MERS-CoV), and the newest SARS-CoV-2 (the causative agent of COVID-19) lead to severe and ...
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MERS-CoV: Understanding the Latest Human Coronavirus Threat
... vaccine against Middle East respiratory syndrome coronavirus (MERS-CoV) infection. Perlman, S.; Vijay, R., Middle East respiratory syndrome vaccines[r] ...
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41579_2013_Article_BFnrmicro3143.pdf
... SARS-CoV mouse models. Epidemic SARS-CoV strains that have been isolated from humans encode receptor- binding domains (RBDs) that interact well with human ACE2. These strains, particularly SARS-CoV Urbani, are capable of ...
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A randomised controlled trial of an open lung strategy with staircase recruitment, titrated PEEP and targeted low airway pressures in patients with acute respiratory distress syndrome
... Introduction: Tidal volume and plateau pressure minimisation are the standard components of a protective lung ventilation strategy for patients with acute respiratory distress syndrome (ARDS). Open lung ...
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