retinoic acid inducible gene I-like receptors
Inhibition of Retinoic Acid-Inducible Gene I-Mediated Induction of Beta Interferon by the NS1 Protein of Influenza A Virus
... type I interferon (alpha and beta interferon [IFN- ␣ /  ]) response constitutes one of the first lines of defense against virus infections ...toll-like receptors (TLR) participate in the detection ...
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Human primary airway epithelial cells isolated from active smokers have epigenetically impaired antiviral responses
... recognition receptors (PRRs). Most cells use the cytosolic sensor, retinoic acid inducible gene I (RIG-I), to detect IAV and trigger antiviral re- sponses ...
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Dengue Virus Subverts the Interferon Induction Pathway via NS2B/3 Protease-IκB Kinase ε Interaction
... recognition receptors (PRRs) detect pathogen-associated molecular patterns (PAMPs), leading to the activation of multiple signaling pathways and transcription factors ...the retinoic ...
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Hsieh, Chin-Yuan (2012): Analysis of Toll-like receptors and retinoic-acid-inducible gene-I (RIG-I)-like helicases in human neutrophils and HL60 cells. Dissertation, LMU München: Medizinische Fakultät
... Neutrophile Granulozyten sind Immunzellen, die vor allem dadurch charakterisiert sind, schnellstmöglich an einen Entzündungs- und Infektionsort zu gelangen. Auf Grund ihrer großen Anzahl im peripheren Blut und ihrer ...
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The development of recombinant Adenoviral vaccines to target pneumovirus infection
... Toll-like receptors (TLRs); TLR3/9 recognises double-stranded RNA and TLR7/8 recognise single-stranded RNA (Kawai, ...type I IFNs and proinflammatory cytokines such as TNF-α (tumour necrosis factor), ...
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Retinoic acid inducible gene I Activates innate antiviral response against human parainfluenza virus type 3
... recognition receptors (PRRs) like toll-like receptors (TLRs) and RLH (RIG like helicases) receptors such as RIGI (retinoic acid inducible gene ...
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Upregulation of Rarb, Rarg, and Rorc Genes in Clear Cell Renal Cell Carcinoma
... stages I–III of clear-cell renal-cell carcinoma and adjacent morphologically normal tissues were taken during surgical resection from patients with primary ccRCC without neoadjuvant ...
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Retinoic acid receptors and nuclear orphan receptors in the development of Xenopus laevis
... Int J Dev lliol 40 255 262 (\ 9%) 255 Retinoic acid receptors and nuclear orphan receptors in the development of Xenopus laevis CHRISTINE DREYER* and HEIDRUN ELLINGER ZIEGELBAUER' Max Planck Institut[.] ...
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Hamm, Wolfgang (2012): Charakterisierung des Liganden des antiviralen Rezeptors Retinoic Acid-Inducible Gene I. Dissertation, LMU München: Medizinische Fakultät
... Um zu zeigen, dass die Erkennung sowie die anschließende Signalweiterleitung nach Stimulation mit 5ʼ-Triphosphat-Haarnadel-RNAs von RIG-I abhängig ist, wurde ein posttranskriptioneller Gen-Knockdown von bestimmten ...
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Expression of retinoic acid-binding proteins and retinoic acid receptors in sebaceous cell carcinoma of the eyelids
... cellular retinoic acid-binding proteins (CRABP1, CRABP2), fatty acid- binding protein 5 (FABP5), retinoic acid receptors -α, −β, and -γ (RAR-α, −β, −γ), and retinoid X ...
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TLR, NLR agonists, and other immune modulators as infectious disease vaccine adjuvants
... Uric acid crystals activate NALP3 inflammasome [46] and it has recently been reported that Influenza virus can induce uric acid in bronchalveolar lavage fluid and serum in mice ...uric acid, which is ...
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Hessel, Esther (2007): Die Rolle von Insulin-Like Growth Factor Binding Protein-2 (IGFBP-2) in der chemisch induzierten Kolonkarzinogenese der Maus. Dissertation, LMU München: Tierärztliche Fakultät
... Die Assays für die TaqMan PCR wurden mit der Online-basierten ProbeFinder Software im Assay Design Center der Universal ProbeLibrary erstellt. Dabei wurden die Sequenzen in den Datenbanken Ensembl, RefSeq und EMBL anhand ...
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Silver nanoparticles impair retinoic acid inducible gene I mediated mitochondrial anti viral immunity by blocking the autophagic flux in lung epithelial cells
... Although previous studies have described that AgNPs could alter the autophagic flux in lung epithelial cells, a phenomenon associated to cytotoxicity, 34 the physiological consequences of autophagy modulation had not ...
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ERF and ETV3L are retinoic acid inducible repressors required for primary neurogenesis
... RAR was predicted to be involved in the pre-patterning stage of neurogenesis, with less pivotal roles during earlier stages of neural induction or the later process of lateral inhibition because treatment with RA ...
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Roles of retinoic acid receptors and of Hox genes in the patterning of the teeth and of the jaw skeleton
... Int I De\' Bioi 39 111 121 (1995) III Roles of retinoic acid receptors and of Hox genes in the patterning of the teeth and of the jaw skeleton MANUEL MARK"?, DAVID LOHNES'+, CATHY MENDELSOHN", VALERIE[.] ...
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COMPREHENSIVE REVIEW ON TREATMENT OF CANCER USING RETINOIC ACID RECEPTORS
... A cell-surface receptor named retinoic acid 6 (STRA6) mediates vitamin A uptake from RBP. Intracellular retinoid bioavailability is regulated by the presence of specific cytoplasmic retinol and ...
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Identification of influential proteins in the classical retinoic acid signaling pathway
... RA metabolism is crucial in RA signaling not only because the CYP can limit the amount of RA available to interact with RARs, but also because some RA metabo- lites can induce the transcription of some target genes ...
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Human serum RNase-L level is inversely associated with metabolic syndrome and age
... RIG‑1: retinoic acid‑inducible gene 1; 2‑5A: ppp5′A[2′p5′A]n; IFN: interferon; MyoD: myogenic differentiation‑1; HuR: Hu antigen R; TTP: tristetraprolin; Pref‑1: pre‑adipocyte factor‑1; CEBP: ...
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Modulation of procollagen gene expression by retinoids Inhibition of collagen production by retinoic acid accompanied by reduced type I procollagen messenger ribonucleic acid levels in human skin fibroblast cultures
... of retinoic acid ethyl ester (RO-10-9359) resulted in a slight increase in procollagen production in these ...all-trans-retinoic acid was accompanied by a similar reduction in pro alpha ...
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Retinoic Acid-Inducible Gene I Mediates Early Antiviral Response and Toll-Like Receptor 3 Expression in Respiratory Syncytial Virus-Infected Airway Epithelial Cells
... including retinoic acid-inducible gene I (RIG-I)- dependent and Toll-like receptor (TLR)-dependent ...IFN-stimulated gene 15 (ISG15) expres- sion levels were ...
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