Salvianolic Acid B
Original Article Salvianolic acid B ameliorates hydrogen peroxide-induced barrier disruption in monolayer Caco-2 cells
... disorders. Salvianolic acid B (Sal B), a natural bioactive component from Salvia miltiorrhiza, has been re- ported to exert protection in various types of ...Sal B on the barrier ...
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Salvianolic acid B, a novel autophagy inducer, exerts antitumor activity as a single agent in colorectal cancer cells
... Salvianolic Acid B (Sal B), an active compound extracted from the Chinese herb Salvia miltiorrhiza, is attracting more and more attention due to its biological activities, including ...
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Original Article Salvianolic acid B reduces brain inflammation and oxidative stress after experimental intracerebral hemorrhage
... vianolic acid B significantly reduced these positive ce- lls when compared to the ICH+vehicle group (Figure ...of Salvianolic acid B signifi- cantly reduced these high- er level as ...
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Study on salvianolic acid B in the reduction of epidural fibrosis in laminectomy rats
... Salvianolic acid B (Sal B), a major bioactive component of the traditional Chinese medical agent, Salvia miltior- rhiza, is widely accepted for use against cardiovascular dis- eases ...Sal ...
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Original Article Protective effect of salvianolic acid B on NASH rat liver through restoring intestinal mucosal barrier function
... of Salvianolic acid B (Sal B) on the disease progress of NASH and change of intestinal barrier ...Sal B every day at a dose of 20 mL/kg body ...Sal B-treated ...Sal B ...
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Salvianolic acid B protects against myocardial damage caused by nanocarrier TiO<sub>2</sub>; and synergistic anti-breast carcinoma effect with curcumin via codelivery system of folic acid-targeted and polyethylene glycol-modified TiO<sub>2</sub> nanoparticles
... folic acid (FA)-targeted and polyethylene glycol (PEG)-modified TiO 2 ...and salvianolic acid B were prepared by emulsion evaporation– solidification at low ...curcumin, salvianolic ...
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Dihydromyricetin and Salvianolic acid B inhibit alpha synuclein aggregation and enhance chaperone mediated autophagy
... [29–31]. Salvianolic acid B (Sal B) is one of the bioactive com- pounds of Salvia miltiorrhiza Bunge extracted from the root of Salvia miltiorrhiza and has been shown to exert various ...
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Hepatoprotective effect of Matrine salvianolic acid B salt on Carbon Tetrachloride-Induced Hepatic Fibrosis
... adopted salvianolic acid B and Matrine as raw materials to prepare Matrine salvianolic acid B salt, which is first reported in this ...Matrine salvianolic acid ...
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Original Article Salvianolic acid B protects against spinal cord injuries via microRNA-21/PTEN/AKT pathways in rats
... Recently, salvianolic acid B (Sal B), a compound extracted from Salvia miltiorrhiza, has been demon- strated to hold antioxidant, anti-inflammatory, and antiapoptotic ...Sal B on spinal ...
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Original Article Salvianolic acid B attenuates lung ischemia-reperfusion injury in rat possibly by inhibiting the P2X7/NLRP3 signaling pathway
... LIRI. Salvianolic acid B (Sal B) is a natural active product extracted from Salvia miltiorrhiza Bge, and protects cardiac myocytes as well as neurons from ischemia-reperfusion ...Sal B ...
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Novel anti infective potential of salvianolic acid B against human serious pathogen Neisseria meningitidis
... Biomax Ultrafree-15 centrifugal filter devises with 100 kDa cut offs were obtained from Millipore. d-biotinoyl-ε-aminocaproic acid-N-hydroxysuccinimide ester, streptavidin-POD conjugate, and ABTS-substrate were ...
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Salvianolic acid B promotes bone formation by increasing activity of alkaline phosphatase in a rat tibia fracture model: a pilot study
... Sal B-treated group at week 1 post-fracture (Figure ...Sal B-treated group (Figure ...Sal B-treated group (Figure 5). These results suggest that Sal B could play a leading role in the ...
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<p>Salvianolic Acid B Improves Chronic Mild Stress-Induced Depressive Behaviors in Rats: Involvement of AMPK/SIRT1 Signaling Pathway</p>
... The activation of AMPK and SIRT1 has been reported to have protective effects on neurons in nervous system diseases. Previous studies have shown that the expression of antioxidant defense related gene could be promoted ...
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Salvianolic acid B protects against lipopolysaccharide-induced behavioral deficits and neuroinflammatory response: involvement of autophagy and NLRP3 inflammasome
... Next, we analyzed the expression of NLRP3 inflamma- some components (Fig. 5). We found that the protein levels of NLRP3 (Fig. 5a, b, p < 0.01) and ASC (Fig. 5d, p < 0.01) were significantly increased in the ...
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Modulation of growth and angiogenic potential of oral squamous carcinoma cells in vitro using salvianolic acid B
... Nucleic acid isolation and cDNA probe preparation Total RNA was isolated from cell culture flasks using RNAbee (Biogenesis), purified using chloroform, precipi- tated using cold isopropanol, washed using 75% ...
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Metabolomic profiles of myocardial ischemia under treatment with salvianolic acid B
... of b-adrenoceptor and decrease the concentration levels of cAMP, PKA and Ca 2+ , lead- ing to slow heart rate, decreased myocardial contracti- lity, reduced cardiac output, and decreased myocardial oxygen ...fatty ...
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Conversion of salvianolic acid B into salvianolic acid A in tissues of Radix Salviae Miltiorrhizae using high temperature, high pressure and high humidity
... The HPLC mobile phase consisted of 0.03% (v/v) formic acid aqueous solution (A) and acetonitrile (B), and its gradient program was the same as those HPLC analysis described above. The mass spectrometer was ...
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Roles of astrocytic connexin-43, hemichannels, and gap junctions in oxygen-glucose deprivation/reperfusion injury induced neuroinflammation and the possible regulatory mechanisms of salvianolic acid B and carbenoxolone
... kinase B (PKB), protein kinase C (PKC), mitogen-activated pro- tein kinase (MAPK), and casein kinase 1 (CK1) ...of salvianolic acids against cerebral I/R injury ...
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Salvianolic acid B reduced the formation of epidural fibrosis in an experimental rat model
... Sal B [13]. To determine whether the Sal B-induced changes in the VEGF levels were dose- dependent, Western blot targeting VEGF was performed at post-operative week 8 in the present ...
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Salvianolic acid B induced upregulation of miR 30a protects cardiac myocytes from ischemia/reperfusion injury
... Sal B could reduce beclin-1 expression, and miR-30a mimics reduced beclin-1 expression ...Sal B. Taken together, these data demonstrate that Sal B can alleviate I – R-injured myocardial cells through ...
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