Scavenger receptor class B
Association of rs5888 SNP in the scavenger receptor class B type 1 gene and serum lipid levels
... The scavenger receptor class B type 1 (SCARB1) is the HDL receptor which binds HDL-C with high ...LDL-C receptor pathway, and plays an important role in reverse cholesterol ...
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Different Requirements for Scavenger Receptor Class B Type I in Hepatitis C Virus Cell-Free versus Cell-to-Cell Transmission
... Hepatitis C virus (HCV) is believed to initially infect the liver through the basolateral side of hepatocytes, where it engages at- tachment factors and the coreceptors CD81 and scavenger receptor ...
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Protein markers of dysfunctional HDL in scavenger receptor class B type I deficient mice
... SR-BI: scavenger receptor class B type I; TC: total cholesterol; TNF-α: tumor necrosis factor α; 2DE: 2D nondenaturing agarose-polyacrylamide gel ...
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Scavenger receptor class B member 1 protein: hepatic regulation and its effects on lipids, reverse cholesterol transport, and atherosclerosis
... Abstract: Scavenger receptor class B member 1 (SR-BI, also known as SCARB1) is the primary receptor for the selective uptake of cholesterol from high-density lipoprotein ...
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Scavenger receptor class B type I regulates cellular cholesterol metabolism and cell signaling associated with breast cancer development
... HDL receptor, the scavenger receptor class B, type I (SR-BI), and subsequent lipid transfer to the cell ...HDL receptor and has been shown to mediate the selective transfer of ...
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Regulation of scavenger receptor, class B, type I, a high density lipoprotein receptor, in liver and steroidogenic tissues of the rat
... The scavenger receptor, class B, type I (SR-BI) binds HDL and mediates the selective transfer of cholesteryl esters from HDL to cultured ...this receptor may deliver HDL-choles- terol ...
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Role of Scavenger Receptor Class B Type I in Hepatitis C Virus Entry: Kinetics and Molecular Determinants
... Scavenger receptor class B type I (SR-BI) is an essential receptor for hepatitis C virus (HCV) and a cell surface high-density-lipoprotein (HDL) ...for receptor oligomerization ...
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Scavenger Receptor Class B Type I and Hepatitis C Virus Infection of Primary Tupaia Hepatocytes
... Human scavenger receptor class B type I (SR-BI) represents an HCV receptor candidate mediating the cellular binding of E2 glycoprotein to HepG2 hepatoma ...
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Hepatic expression of scavenger receptor class B type I (SR BI) is a positive regulator of macrophage reverse cholesterol transport in vivo
... Plasma levels of HDL cholesterol (HDL-C) and its major protein apoA-I are inversely associated with the risk of atherosclerotic vas- cular disease. One mechanism by which HDL and apoA-I protect against atherosclerosis is ...
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The rs5888 single nucleotide polymorphism in scavenger receptor class B type 1 (SCARB1) gene and the risk of premature coronary artery disease: a case-control study
... Scavenger receptor class B type1 (SCARB1, also called SR-BI) is a multiligand cell surface receptor expresses both in macrophages and in the liver, indicating a major role for in the ...
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Scavenger Receptor Class B type 1 (SR-B1) and the modifiable risk factors of stroke
... SR-B1 is a complex receptor affected by many comor- bidities associated with stroke. The current literature shows that SR-B1 has both positive and negative effects. Some of the risk factors, such as smoking and ...
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Human scavenger receptor class B, type II (SR-BII) and cellular cholesterol efflux
... The selected transformants continued to grow on selection plates, suggesting that the yeast cells contained both expression plasmids. However, it was necessary to confirm that the required fusion proteins were being ...
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Scavenger Receptor Class B Is Required for Hepatitis C Virus Uptake and Cross-Presentation by Human Dendritic Cells
... BII overexpressed in nonphagocytotic human epithelial cells have been shown to mediate the binding and uptake of live, as well as dead, gram-negative and gram-positive bacteria, sug- gesting a conserved role for SR-BI ...
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Scavenger receptor class B type I is a multiligand HDL receptor that influences diverse physiologic systems
... Initially, scavenger receptor activity was identified as “AcLDL receptor activity” by Brown, Gold- stein, and colleagues (2), who were developing an in vitro model for the deposition of LDL ...
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Expression of the Scavenger Receptor Class B type I (SR BI) family in Drosophila melanogaster
... The Scavenger Receptors Class B Type I (SR-BI) are membrane proteins that belong to the CD36 family and participate in the selective uptake of high density lipoprotein cholesteryl ester in the ...
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The Tight Junction-Associated Protein Occludin Is Required for a Postbinding Step in Hepatitis C Virus Entry and Infection
... The precise mechanisms regulating hepatitis C virus (HCV) entry into hepatic cells remain unknown. However, several cell surface proteins have been identified as entry factors for this virus. Of these molecules, ...
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Glycine N-Methyltransferase Deficiency Affects Niemann-Pick Type C2 Protein Stability and Regulates Hepatic Cholesterol Homeostasis
... (ABCG1), scavenger receptor class B type 1 (SR-B1), 3-hydroxy-3-methyl-glutaryl- coenzyme A reductase (HMGCR), Niemann-Pick type C1 protein (NPC1), lysosome-associated membrane protein 1 ...
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Original Article Relationship between SR-BI genetic polymorphism and coronary heart disease and blood lipid level
... of scavenger receptor class B type I (SR-BI) exon 1 and intron 5 on blood lipid level and susceptibility to coronary heart disease (CHD) of Chinese Han popula- tion in ...
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Lupin protein isolate versus casein modifies cholesterol excretion and mRNA expression of intestinal sterol transporters in a pig model
... Methods: Two groups of pigs were fed cholesterol-containing diets with either 230 g/kg of lupin protein isolate from L. angustifolius or 230 g/kg casein, for 4 weeks. Faeces were collected quantitatively over a 5 d ...
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Scavenger Receptor CD163 and Its Biological Functions
... of scavenger receptor class B with a majority of functions that still remain unclear, however it has several applications in clinical medicine where its soluble form has a biological ...
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