Screening Trial
Estimates of sensitivity and specificity can be biased when reporting the results of the second test in a screening trial conducted in series
... negative screening trial are differ- ent than estimates obtained from a trial design that utilizes only a single ...the trial that supplied ...series trial design, and 2) correct for ...
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Applying quantitative bias analysis to estimate the plausible effects of selection bias in a cluster randomised controlled trial: secondary analysis of the Primary care Osteoarthritis Screening Trial (POST)
... ritis Screening Trial (POST) – a pragmatic, cluster randomised, parallel, two-arm trial in primary care in which 45 practices were block-randomised 1:1 to inter- vention or control using a balance ...
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The Danish Cardiovascular Screening Trial (DANCAVAS): study protocol for a randomized controlled trial
... An offer for screening is known to reduce the quality of life in the period leading up to the examination, but the effect fades out in the absence of a positive finding. It is unclear if a sustained reduction in ...
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Standardisation of information submitted to an endpoint committee for cause of death assignment in a cancer screening trial – lessons learnt from CAP (Cluster randomised triAl of PSA testing for Prostate cancer)
... cancer screening trials differential misclassification may arise from two well-known sources of potential death certificate ...the screening process itself which are not traced back to screening but ...
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Bias in trials comparing paired continuous tests can cause researchers to choose the wrong screening modality
... Cancer screening trials in particular are susceptible to paired screening trial bias, because the secondary test is typ- ically ...Negative screening results cannot lead to biopsy because ...
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Overdiagnosis and overtreatment of breast cancer: Estimates of overdiagnosis from two trials of mammographic screening for breast cancer
... mammographic screening confers a substantial and significant reduction in breast cancer ...a screening programme, which has led to concerns about overdiagnosis, that is to say, the diagnosis of disease ...
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Participation in lung cancer screening programs: are there gender and social differences? A systematic review
... of screening trials for early detection of lung cancer have been, or are be- ing, conducted using both chest X-ray (CXR) and low-dose computed tomography (LDCT) ...LDCT screening led to a substantial 20% ...
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2040.pdf
... recommend screening in an asymptomatic population at this ...of screening, the evidence is either of poor quality (key questions one and two) or entirely lacking (key questions three and ...a ...
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Treating anxiety after stroke (TASK): the feasibility phase of a novel web-enabled randomised controlled trial
... large trial. Feasibility of remotely performed trial procedures need to be tested in stroke and TIA patients: online self-screening and recruitment, remote eligibility confirmation, electronic ...
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A randomized controlled trial of eicosapentaenoic acid and/or aspirin for colorectal adenoma prevention during colonoscopic surveillance in the NHS Bowel Cancer Screening Programme (The seAFOod Polyp Prevention Trial): study protocol for a randomized controlled trial
... at screening colonoscopy on the basis of aden- oma number and (endoscopic) size, confirmed later by the histopathology ...Specialist Screening Practitioner (SSP) or Research Nurse (RN) when the histological ...
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Can a combined screening/treatment programme prevent premature failure of renal transplants due to chronic rejection in patients with HLA antibodies: study protocol for the multicentre randomised controlled OuTSMART trial
... In summary, this trial will identify a group of patients at high risk of premature transplant failure. Therapy will be optimised for these at-risk patients, many of whom will be identified before they have started ...
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A Randomized Trial on Screening for Social Determinants of Health: the iScreen Study
... before screening is widely ...Our screening tool was designed for 1-way communication from patients to clini- cal providers (in this case, study staff) and focused exclusively on disclosure rates between ...
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Systems intervention to promote colon cancer screening in safety net settings: protocol for a community-based participatory randomized controlled trial
... CRC screening as well as increase the likelihood that screening is referred and com- ...randomized trial using Community-Based Participatory Research (CBPR) methods, we met with our Colon Cancer ...
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Update to the study protocol, including statistical analysis plan, for the multicentre, randomised controlled OuTSMART trial: a combined screening/treatment programme to prevent premature failure of renal transplants due to chronic rejection in patients with HLA antibodies
... Length of follow-up was amended to be variable such that each participant will undergo 32 months of inten- sive follow-up post randomisation (or additionally 32 months after becoming HLA Ab+ at one of the re- ...
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Recruitment of young women to a trial of chlamydia screening – as easy as it sounds?
... this trial: young, multi- ethnic sexually active female students from 11 Further Education (FE) colleges and 11 universities in Greater ...this trial and the methods developed to try and overcome them ...
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Evaluation of a toolkit to improve cardiovascular disease screening and treatment for people with type 2 diabetes: protocol for a cluster randomized pragmatic trial
... and screening for cardio- vascular disease; and a pad of tear-off sheets for patients with a cardiovascular risk self-assessment tool and a list of recommended risk reduction ...
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Effectiveness and cost effectiveness of routine third trimester ultrasound screening for intrauterine growth restriction: study protocol of a nationwide stepped wedge cluster randomized trial in The Netherlands (The IRIS Study)
... of screening for and management of IUGR and is, therefore, expected to have important clinical ...ultrasound screening on maternal prenatal and post- natal psychological functioning and on long-term ...
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Selection of resistance sources to common bean anthracnose by field phenotyping and DNA marker-assisted screening
... field trial to screen the common bean genotypes for reaction to anthracnose was carried out at Embrapa Arroz e Feijão (Santo Antônio de Goiás, GO, Brazil), during the fall/winter growing season of 2014, using a ...
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The feasibility and acceptability of trial procedures for a pragmatic randomised controlled trial of a structured physical activity intervention for people diagnosed with colorectal cancer: findings from a pilot trial of cardiac rehabilitation versus usual care (no rehabilitation) with an embedded qualitative study
... has recently reported that staff did not approach people who ‘do not look like an exerciser’ [46]. Hence, research teams should make an effort to ensure that all staff de- fine eligibility criteria appropriately. If ...
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Delayed Diagnosis of Kawasaki Disease: What Are the Risk Factors?
... tively explored the reasons for diagnosis after day 10 of illness during an outbreak in Colorado. In contrast to our prospective study in which 16% of children received the diagnosis after day 10 of illness, they found ...
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