secondary injury
Neuroprotection from secondary injury by polyethylene glycol requires its internalization
... The issue of a possible action of PEG in reducing the severity of secondary injury seemed likely to depend on PEG entering cells that have relatively intact cell membranes, but are compromised. Such ...
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Natural IgM antibodies that bind neoepitopes exposed as a result of spinal cord injury , drive secondary injury by activating complement
... mice. Injury correlated with colocalized deposition of IgM and C3d in injured spinal cords from both mAb reconstituted Rag1 − / − mice and untreated wild-type ...
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Osthole confers neuroprotection against cortical stab wound injury and attenuates secondary brain injury
... following injury was also associated with a lower number of microglia/ macrophages and neutrophils at the injury site and re- duced levels of the proinflammatory cytokines IL-6 and ...reduce ...
11
Targeted disruption of the beta chemokine receptor CCR1 protects against pancreatitis associated lung injury
... of secondary injury in this ...pancreatic injury results directly in chemokine synthesis within this organ, which leads to local amplification of cyto- kine ...pancreatic injury to the ...
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Traumatic Spinal Cord Injury; Theranostic Applications of Advanced MRI Techniques
... of injury to spinal white matter tracts. Thus, as a biomarker for injury severity, DTI measurements of diffusion throughout the spinal cord after an injury might be taken into ...the secondary ...
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Individualized perfusion targets in hypoxic ischemic brain injury after cardiac arrest
... mitigate secondary injury in HIBI and are sup- ported by emerging observational literature, guideline statements recommend a MAP threshold of ≥ 65 mmHg ...
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2504.pdf
... Review of the secondary injury theory of acute spinal cord trauma with emphasis on vascular mechanisms. Chapman JR, Anderson PA[r] ...
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Nanomedicine strategies for treatment of secondary spinal cord injury
... immune system, reducing inflammation around the injury site. Although it may attenuate oxidative stress and cytok ines from immune cells, it does not address the process of stress from dead or dying cells. ...
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PubMedCentral-PMC5220558.pdf
... the secondary injury phase of TBI induces dysfunction in glutamate reuptake transporters and exacerbates the deleterious effects of elevated extracellular ...
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The effect of erythropoietin to pulmonary injury and mast cells secondary to acute pancreatitis
... Background: Acute pancreatitis is a life-threatening necroinflammatory disease that is characterized by systemic inflammatory response syndrome and acute lung injury even in its very first days. Erythropoietin ...
6
Molecular mechanisms of inflammation and tissue injury after major trauma-is complement the "bad guy"?
... cell injury after complement activation ...brain injury renders neurons vulnerable to MAC-mediated lysis by shedding of the glycosyl-phos- phatidyl-inositol (GPI)-anchored glycoprotein CD59 from neuronal ...
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Beyond intracranial pressure: optimization of cerebral blood flow, oxygen, and substrate delivery after traumatic brain injury
... Under physiological conditions, the relationship between CBF and CPP is linked to the cerebral autoregulatory capacity, thus CBF remains constant over a wide range of CPP. After TBI, depending on the nature of the lesion ...
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Clinical spectrum and therapeutic approach to hepatocellular injury in patients with hyperthyroidism
... the patient had developed drug-induced hepatotoxicity. She was followed up as an outpatient and showed progres- sive elevation of hepatic enzymes, although thyroid tests had reverted to normal. Antismooth muscle ...
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Viability-Dependent Promoting Action of Adult Neural Precursors in Spinal Cord Injury
... (A) Schematic drawing of the transverse spinal cord at the level of the lesion in NSC- transplanted cells animals. The green fluorescent cells transplanted by endovenous in- jection, and which reached the site of the ...
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Acute kidney injury secondary to thrombotic microangiopathy associated with idiopathic hypereosinophilic syndrome: a case report and review of the literature
... Idiopathic hypereosinophilic syndrome (HES) is charac- terized by an absolute eosinophil count greater than 1500 cells/mm 3 observed at least twice with a minimum interval of 4 weeks, multiorgan involvement, and pres- ...
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Antioxidant activity of pomegranate juice reduces emphysematous changes and injury secondary to cigarette smoke in an animal model and human alveolar cells
... Results: Acutely, a significant increase in interleukin (IL)-1β, IL-6, and tumor necrosis factor (TNF)-α expression, apoptosis, and OS was noted in CS when compared to Control. PJ significantly attenuated the expression ...
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Minimal surgery achieved good visual acuity in selected patients with magnetic intravitreal foreign body and traumatic cataract
... no secondary glau- coma, endophthalmitis, or retinal injury and identifica- tion of the metallic-like foreign body suspended in the vitreous cavity, primary removal of IVFD was performed by direct external ...
5
Original Article Celastrol attenuates ventilator induced lung injury in mouse through inhibition of MAPK pathway
... USA), secondary antibodies and phosphate buffer saline (Beyotime Institute of Biotechnology, China), Chemiluminescence detection kit (Millipore, USA), SYBR Green PCR kit for real time PCR (Thermo, USA), reverse ...
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Motivational Interviewing to Reinforce Coping and Improve Quality of Life in Patients with Spinal Cord Injury
... pinal Cord Injury (SCI) often occurs unex- pectedly. It may be caused as a result of falls, road traffic accidents, assaults, or pathologi- cal processes like the tuberculosis of the spine [1, 2]. However, the ...
6
Post traumatic glenohumeral cartilage lesions: a systematic review
... example of a focal humeral cartilage lesion is shown in Figure 2. Cartilage lesions on the convex surface of the humeral head may be due to high compressive or shearing forces [23,28]. Dislocation and subluxation are ...
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