Serine peptidase
Inhibitor of serine peptidase 2 enhances Leishmania major survival in the skin through control of monocytes and monocyte-derived cells
... Leishmania can directly modulate DC signaling and responses, such as their capacity to migrate, mature, present antigen, and produce cytokines (49, 50). In this study, we demonstrated that L. major inhibits the ...
18
The PDZ domain of the SpoIVB serine peptidase facilitates multiple functions
... FIG. 1. The SpoIVB PDZ domain. (A) Schematic diagram showing the position of the PDZ domain of SpoIVB (residues 102 to 187). The arrow indicates the site of the first self-cleavage reaction in the SpoIVB polypeptide. ...
11
Trypsin like serine peptidase profiles in the egg, larval, and pupal stages of Aedes albopictus
... The pupal stage exhibited a complex and stage-specific proteolytic profile, composed of six bands of activity. Compared to the larval profile, which showed activities in a wide pH range (3.5 – 10), the pupal stage ...
11
Campylobacter jejuni gene cj0511 encodes a serine peptidase essential for colonisation
... jejuni peptidase-related gene htrA is required for heat-shock resistance, oxygen tolerance and invasion of INT407 human epithelial cells ...another peptidase, ClpP, is associated with a biofilm formation ...
5
Analysis of the individual and aggregate genetic contributions of previously identified serine peptidase inhibitor Kazal type 5 (SPINK5), kallikrein related peptidase 7 (KLK7), and filaggrin (FLG) polymorphisms to eczema risk
... inherited, but is not a major genetic contributor to eczema risk • A previously reported association of a KLK7 insertion and eczema could not be confirmed • There is no evidence for epis[r] ...
36
The Bacillus subtilis signaling protein SpoIVB defines a new family of serine peptidases
... of serine peptidase families, especially those of the PA(S) clan (23, 24), and is found at position 363, and we take this as evidence that the SpoIVB serine peptidase has a cata- lytic triad ...
10
Comparative Genomic Studies of hypothetical proteins in Cyanophages
... (GPO) serine peptidase ; SlyX ; Baculovirus polyhedron envelope protein, PEP, C terminus ; FlgN protein ; Prominin ; Tat binding protein 1(TBP-1)-interacting protein (TBPIP) ;Axonemal dynein light chain ; ...
18
Increased expression of antisense lncRNA <em>SPINT1-AS1</em> predicts a poor prognosis in colorectal cancer and is negatively correlated with its sense transcript
... In the current study, we focused on one of the NATs termed serine peptidase inhibitor, Kunitz type 1 antisense RNA1 (SPINT1-AS1). Until now, the status of SPINT1-AS1 in CRC has not been explored; thus, we ...
10
Novel host genetic variations associated with spontaneous clearance of a single source outbreak of HCV1b infections
... protease serine 11A (TMPRSS11A), and one in the serine peptidase inhibitor kunitz type 2 (SPINT2) showed the closest associations ( p<10 − 5 ...
9
Proteolytic profiling and comparative analyses of active trypsin like serine peptidases in preimaginal stages of Culex quinquefasciatus
... trypsin-like serine peptidase activities were observed during the time-course assays (24 h for eggs, 2 h for larvae and 12 h for ...trypsin-like serine peptidase repertoire may help larvae to ...
11
<p>Decreased expression of SPINT1-AS1 and SPINT1 mRNA might be independent unfavorable prognostic indicators in esophageal squamous cell carcinoma</p>
... In this study, we investigated the expression of SPINT1-AS1 in matched ESCC and normal tissues by quantitative real-time polymerase chain reaction (qRT- PCR) method. We further analyzed the relationship between ...
9
Specificity of Coxsackievirus B3 Interaction with Human, but Not Murine, Decay-Accelerating Factor: Replacement of a Single Residue within Short Consensus Repeat 2 Prevents Virus Attachment
... Based on previous observations (4, 5, 14), we suspected that the specificity of virus binding would reside within the SCR domains rather than within the membrane-proximal serine-threonine do- main. To confirm ...
5
Vigilin interacts with signal peptide peptidase
... An alternative effect of the SPP-vigilin interaction is that vigilin could modulate the putative functions of SPP in protein quality control in the ER. Testing this hypoth- esis will req[r] ...
13
Leptinreceptorgenepolymorphism and its relationship with functional traits in Baluchi sheep using PCR SSCP
... is. Serine was converted to the amino acid glutamate. Serine compound is involved in the manufacture of fat and ...protein. Serine was converted to ...
6
The nucleotide binding oligomerization domain containing protein 1 (NOD1) polymorphism S7N does not affect receptor function
... these, serine 7 and tyrosine 49 are also found as rare polymorphisms in the African-American population and European-American populations ...Mutating serine 7 to either an aspartic acid or an asparagine to ...
5
Characterization of a novel variant of the second domain of bikunin with increased leukocyte elastase inhibitory activity
... with serine proteases using the crystal structure of the Kunitz protease inhibitor domain of protease nexin 2 complexed with human factor XIa as a reference to identify novel ...
10
Identification and characterisation of gut proteases in the fig tree skeletoniser moth, Choreutis nemorana Hübner (Lepidoptera: Choreutidae)
... Insects need an adequate source of protein in order to grow and maintain themselves. Proteins comprised in amino acids and these organic com- pounds are fundamental for growth, reproduction, and as a structural element ...
8
Epstein-Barr Virus LMP1 Activates EGFR, STAT3, and ERK through Effects on PKCδ
... on serine and tyrosine and treatment with EGF induced abundant tyrosine phosphorylation of STAT3 and expression of a subset of known STAT3 target genes ...serum-independent serine phosphorylation of STAT3, ...
10
<p>Inhibition of Serine Metabolism Promotes Resistance to Cisplatin in Gastric Cancer</p>
... extra serine relative to those recorded in cells treated with cisplatin and NCT-503 (Figure 2G and ...with serine restored the sensitivity of gastric cancer cells to this chemotherapeutic ...
10
DOSAGE COMPENSATION OF SERINE-4 TRANSFER RNA IN DROSOPHILA MELANOGASTER
... Although the analysis is compli- cated by the fact that not all of the serine genes are present at 12DE, by the possibility that serine genes other than isoaccep[r] ...
13