Shanghai (China) Population

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Population dynamics of Neisseria gonorrhoeae in Shanghai, China: a comparative study

Population dynamics of Neisseria gonorrhoeae in Shanghai, China: a comparative study

Changes in relative Ne over time represent a valuable tool for inferring the current and past epidemiology of infectious diseases. Our analysis of population dynamics of N. gonorrhoeae over the past 40 years in Shanghai, inferred from the housekeeping genes, showed that rela- tive Ne has been increasing since the early 1980s with a leveling off from 2002 until 2005. The inference made from the porB gene was similar to that observed with the housekeeping genes. In contrast, the fluoroquinolone resistance genes showed a declining relative Ne since 1985. The appearance of antibiotic resistant strains would be predicted to cause a decrease in relative Ne since a limited number of strains with resistance muta- tions would have a selective advantage. This expectation was born out by the BEAST analysis of the fluoroquino- lone resistance genes. Additionally, a decrease in relative Ne estimated from the housekeeping and porB genes would also be predicted, due to a selective sweep. How- ever, the opposite pattern was observed in this popula- tion: relative Ne estimated from these genes increased (Figure 2). The most likely explanation for this finding is that fluoroquinolone antibiotics continue to be used widely in China and their continued use led to rapid diversification as the resistance genes spread throughout the gonococcal population. The evolutionary pattern of a rising relative Ne in housekeeping genes in the pre- sence of a declining relative Ne for resistance genes may have therefore broad application in clinical practice as an indication that antibiotics are being misused and the need for better strategies for managing the resistance. However, we cannot exclude the possibility that social and epidemiological factors also contributed to the increase in relative Ne inferred from the housekeeping and porB genes. The rise in incidence of gonorrhea in late 1990s has been mainly attributed to the influx of people into Shanghai and to economic development attracting more construction workers from the country- side to that area. This movement of people may have resulted in the importation of new strains into the city, fueling the increase in relative Ne. Conversely, the recent leveling off or decline in relative Ne observed in

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Investigation of Streptococcus pyogenes Carriage in Population Vulnerable to Scarlet Fever during 2015 2017 in Shanghai, China

Investigation of Streptococcus pyogenes Carriage in Population Vulnerable to Scarlet Fever during 2015 2017 in Shanghai, China

This study aimed to investigate the carriage of Streptococcus pyogenes in population vulnerable to scarlet fever and to compare their genotypic charac- terization between different age groups. Pharyngeal swabs were collected from 120 - 150 students in each of the three districts in Shanghai in May and December during 2015 to 2017, while emm typing and detection of 12 superan- tigen genes were performed to characterize the isolates. During 2015-2017, the average carriage rate in students was 5.7% (135/2,371), without significant difference between different years or districts. The carriage rate was signifi- cantly different between children from the three age groups, with 2.4% in 3 - 4 years, 5.4% in 5 - 9 years, and 9.1% in 10 - 14 years. Eight emm types were found, including emm 1, emm 4, emm 12, emm 22, emm 75, emm 89, emm 70 and emm 241, among which emm 12 accounted for 60%, and emm 1 27.5%. The predominance of emm 12 was found in each year, but the propor- tion of emm 12 was lower in 10 - 14 years (43.3%) than in 3 - 4 years (86.7%) and in 5 - 9 years (73.3%) ( P = 0.002 and 0.003). Superantigen genes of speB , speC , speG , ssa and smeZ were found in almost all the isolates. The average carriage of S. pyogenes in population vulnerable to scarlet fever was 5.7% in Shanghai, highest in 10 - 14 years (9.1%), while emm 12 was the predominant type.

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Familial aggregation and heritability of hypertension in Han population in Shanghai China: a case-control study

Familial aggregation and heritability of hypertension in Han population in Shanghai China: a case-control study

Tibetan (77.2%) [27]. it indicates that there are also eth- nic differences in hypertension susceptibility genes among different ethnic groups. In this study, the herit- ability of second-degree relatives and third-degree rela- tives were respectively 23.42 and 21.41%. The order of hypertension heritability was as follows: first-degree rela- tives > second- degree relatives > third-degree relatives. From the above stratified analysis results, the effect of genetic factors on the incidence of essential hypertension may be more obvious in first-degree relatives, and fell obviously as the level of kinship declined. The above re- sults show that the occurrence of hypertension in the Han population in Shanghai, China, is affected by both genetic and environmental factors, which is consistent with the reports of relevant manufacturers [28–30]. The formation of polygenic diseases is influenced by both the Table 2 The hypertension prevalence rate (%) of relatives in case and control group

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Association Between Family History and the Onset Age of Essential Hypertension in Han Population in Shanghai China

Association Between Family History and the Onset Age of Essential Hypertension in Han Population in Shanghai China

Abstract: Genetic factor is one of important influencing factors of essential hypertension, and family history (FH) is an important marker of genetic factors. To explore the association between family history and the onset age of essential hypertension in Han population in Shanghai China. According to l:l matched pairs design, 342 cases of hypertension and 342 controls were selected and investigate their nuclear family members in the case-control study. The diagnostic information of hypertension in all relatives of these two groups was investigated. The method of genetic epidemiology research was used to explore the effect of family history. The average prevalence of hypertension was 23.32%. The prevalence of hypertension of first-degree relatives was 33.99%; the prevalence of second- degree relatives was 17.60%; the prevalence of third-degree relatives was 13.51%. All prevalence of hypertension of case group relatives were significantly higher than that of control group relatives. The average onset age in population with positive FH is 48.74±11.16 years old, and the average onset age in population with negative FH is 54.38±9.87 years old. The difference about two FH groups showed statistically significant (t=4.589, P<0.001). The average onset age of offspring with father, mother, grandpa, grandma, maternal grandpa or maternal grandma positive was respectively 48.42± 11.16, 49.16±11.12, 39.55±11.95, 39.88±11.90, 43.67±9.77 or 43.64±10.21 years old; and the average onset age of children with father, mother, grandpa, grandma, maternal grandpa or maternal grandma negative was respectively 51.90± 10.81, 51.17±11.04, 51.07±10.59, 51.08±10.60, 50.50±11.09 or 50.57±11.06 years old. The difference about two groups showed statistically significant. Family history has a positive effect on the occurrence of hypertension, and lead to earlier age of onset of offspring. The effects are different among parent and grandparent in Han in Shanghai China.

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Kaposi`s sarcoma associated herpesvirus infection among female sex workers and general population women in Shanghai, China: a cross sectional study

Kaposi`s sarcoma associated herpesvirus infection among female sex workers and general population women in Shanghai, China: a cross sectional study

Currently, There is limited information on the trans- mission routes for KSHV infection in mainland Chinese populations. Moreover, no data is available for KSHV seroprevalence among sex workers in China, who have been found to be at high risk of sexually transmitted in- fections (STIs) including HIV. To determine whether heterosexual transmission of KSHV occurs frequently among female sex worker (FSW) is an important public health concern because of the link with HIV, and its po- tential threat to other populations. FSWs could poten- tially play a critical bridging role in spreading KSHV from their high-risk sexual partners to low-risk popula- tions, if a heterosexual transmission route of KSHV could be established. Understanding seroprevalence and potential risk factors of KSHV infection is a prerequisite for the prevention strategy for KSHV transmission and the subsequent diseases associated with this important oncogenic infection. Therefore, we conducted a cross- sectional study among a group of FSWs and a group of general population women (GW) in Shanghai, China, to explore the potential of heterosexual transmission of KSHV infection in China. In parallel, well established STIs including syphilis, HBV, HIV, and particularly herpes simplex virus 2 (HSV-2) infections were also examined. If KSHV could be transmitted through heterosexual con- tacts, we would expect to observe a higher prevalence of KSHV infection as well as higher prevalences of well established STIs such as syphilis and HSV-2 infections among risk-taking FSWs than low risk GW. We be- lieved that FSW, who were engaging in high risk hetero- sexual practices and were at risk for STIs, will provide a unique setting to gain insights into the possibility of heterosexual transmission of KSHV.

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Accuracy of self-reported cancer treatment data in young breast cancer survivors

Accuracy of self-reported cancer treatment data in young breast cancer survivors

Only three prior studies assessed recall of specific chemotherapy medications received, with variable results [5, 8, 9]. In 895 Australian women diagnosed with breast cancer between 1991 and 1998, agreement regarding specific chemotherapy regimens with a median recall period of 3.2 years ranged from 76 to 93% [5]. Another study of 939 Canadian women diagnosed between 1996 and 1998 with a median recall period of 3.0 years found that agreement rates regarding the specific type of medi- cations received ranged from 90 to 98% for endocrine therapies and from 55 to 89% for chemotherapies [8]. A population-based study of 5042 women diagnosed with breast cancer between 2002 and 2006 in Shanghai, China with a median time from diagnosis of 6.5 months identi- fied that agreement rates between medical records and patient self-report of chemotherapy ranged from 82 to 98% for the ten most commonly prescribed chemother- apy medications [7]. However, breast cancer treatments have become more complex in recent years. For example, trastuzumab +/− pertuzumab are two targeted therapies which are now used in most patients with human epidermal growth factor receptor [Her2]-positive tumors, and new endocrine treatment strategies are available including the combination of an aromatase inhibitor (letrozole, anastrozole, or exemestane) with a gonadotropin-releasing hormone agonist (e.g., goserelin or leuprolide) for women with premenopausal estrogen receptor [ER]-positive disease. None of these prior stud- ies included women diagnosed after 2006. One more recent study that evaluated the accuracy of self-report of fertility-threatening cancer treatments in 101 young cancer survivors of various cancer types including lymphoma, breast cancer, uterine cancer, and ovarian cancer found only a 68% accuracy of reporting exposure to alkylating agents at a median recall period of 2.4 years [11]. The objective of our study was to assess the accur- acy of patient self-reports of breast cancer treatments including newer chemotherapy regimens, targeted ther- apy, and endocrine therapy in a group of young breast cancer survivors.

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Original Article Prevalence of maternal passive smoking and its impact on pregnancy following implementation of an anti-smoking legislation in Shanghai, China: a cross-sectional study

Original Article Prevalence of maternal passive smoking and its impact on pregnancy following implementation of an anti-smoking legislation in Shanghai, China: a cross-sectional study

plementation of the Regulations on the Admi- nistration of Sanitation at Public Places” anti- smoking legislation, which included a ban on smoking in any indoor public place, was issued in 2011. Although there have been studies on the effects of the anti-smoking legislation on smoking prevalence and human health [12, 13], there have been less information on the impact of maternal passive smoking during pregnancy. Shanghai, as one of the largest cit- ies and with a large “floating population”, is rep- resentative of other cities in China with similar population patterns. Thus, we conducted a cross-sectional study in a tertiary maternal and infant hospital in Shanghai, to investigate the prevalence of maternal passive smoking and its impact on pregnancy complications and neonatal outcomes following the nationwide implementation of the indoor places anti-smok- ing legislation.

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Maternal age at menarche and offspring body mass index in childhood

Maternal age at menarche and offspring body mass index in childhood

Three previous studies from developed countries found that early maternal age of menarche (MAM) was associated with rapid infant growth and childhood obes- ity in offspring [8 – 10]. Another study also showed that women with earlier MAM were more likely to have overweight children at 4 to 5 years of age [11]. However, little is known as to the relationship of MAM with off- spring BMI beyond preschool stage into childhood in a developing country. Childhood is a critical stage for the establishment of adipose tissue and contributes to the development of adiposity in the later life [12]. Thus, to further examine the intergenerational role of MAM played in childhood body mass index (BMI), we took advantage of a large population-based cross-sectional study, ‘ the Shanghai Children ’ s Health, Education and

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Search for anomalous electroweak production of WW/WZ in association with a high-mass dijet system in pp collisions at root S=8 TeV with the ATLAS detector

Search for anomalous electroweak production of WW/WZ in association with a high-mass dijet system in pp collisions at root S=8 TeV with the ATLAS detector

We acknowledge the support of ANPCyT, Argentina; YerPhI, Armenia; ARC, Australia; BMWFW and FWF, Austria; ANAS, Azerbaijan; SSTC, Belarus; CNPq and FAPESP, Brazil; NSERC, NRC and CFI, Canada; CERN; CONICYT, Chile; CAS, MOST and NSFC, China; COLCIENCIAS, Colombia; MSMT CR, MPO CR and VSC CR, Czech Republic; DNRF and DNSRC, Denmark; IN2P3-CNRS, CEA- DSM/IRFU, France; GNSF, Georgia; BMBF, HGF, and MPG, Germany; GSRT, Greece; RGC, Hong Kong SAR, China; ISF, I-CORE and Benoziyo Center, Israel; INFN, Italy; MEXT and JSPS, Japan; CNRST, Morocco; FOM and NWO, Netherlands; RCN, Norway; MNiSW and NCN, Poland; FCT, Por- tugal; MNE/IFA, Romania; MES of Russia and NRC KI, Russian Federation; JINR; MESTD, Serbia; MSSR, Slovakia; ARRS and MIZŠ, Slovenia; DST / NRF, South Africa; MINECO, Spain; SRC and Wal- lenberg Foundation, Sweden; SERI, SNSF and Cantons of Bern and Geneva, Switzerland; MOST, Tai- wan; TAEK, Turkey; STFC, United Kingdom; DOE and NSF, United States of America. In addition, individual groups and members have received support from BCKDF, the Canada Council, CANARIE, CRC, Compute Canada, FQRNT, and the Ontario Innovation Trust, Canada; EPLANET, ERC, FP7, Horizon 2020 and Marie Skłodowska-Curie Actions, European Union; Investissements d’Avenir Labex and Idex, ANR, Région Auvergne and Fondation Partager le Savoir, France; DFG and AvH Foundation, Germany; Herakleitos, Thales and Aristeia programmes co-financed by EU-ESF and the Greek NSRF; BSF, GIF and Minerva, Israel; BRF, Norway; Generalitat de Catalunya, Generalitat Valenciana, Spain; the Royal Society and Leverhulme Trust, United Kingdom.

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Analysis of risk factors for cervical lymph node metastasis of papillary thyroid microcarcinoma: a study of 268 patients

Analysis of risk factors for cervical lymph node metastasis of papillary thyroid microcarcinoma: a study of 268 patients

This retrospective study analyzed the clinical data of pathologically proven PTMC patients who were initially treated at Shanghai Ruijin Rehabilitation Hospital, Shanghai, China, between October 2017 and January 2019. Patients were included if 1) they received initial diagnosis and treatment for thyroid nodules; 2) they were diagnosed with PTMC by preoperative fine-needle biopsy and underwent conventional lobectomy of thy- roid carcinoma; 3) they had pathologically proven

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The clinical efficacy of Shi-style lumbar manipulations for symptomatic degenerative lumbar spondylolisthesis: protocol for a randomized, blinded, controlled trial

The clinical efficacy of Shi-style lumbar manipulations for symptomatic degenerative lumbar spondylolisthesis: protocol for a randomized, blinded, controlled trial

After the screening, patients will be randomized into two groups with an allocation ratio of 1:1. The randomization will be generated via SAS PROC PLAN software (SAS Inc., Cary, NC, USA) by an independent third-party clin- ical research organization (Institute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Science) and concealed from the researchers by a senior data manager who is not involved in the study. The group assignment list will be sealed in opaque envelopes and be opened by the researchers following informed consent procedures and baseline testing.

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catena Poly­[[silver(I) μ 4,4′ bi­pyridine κ2N:N′] perchlorate]

catena Poly­[[silver(I) μ 4,4′ bi­pyridine κ2N:N′] perchlorate]

The authors acknowledge ®nancial support from the National Science Foundation of China (grant No. 30100118), the National Science Foundation of Shanghai (grant No. 03ZR14073) and the Youth Science Foundation of Shanghai Higher Education (grant No. 03DQ23), and a Science Grant (No. 870) of the Key Subject of Applied Chemistry (No. 1) of Shanghai Teachers' University.

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Original Article Flora regulation of BuzhongYiqi decoction in patients with food allergies after surgery for anal fistula

Original Article Flora regulation of BuzhongYiqi decoction in patients with food allergies after surgery for anal fistula

trol group. sIgE was used to screen the aller- gens (n=14). Patients with blood diseases, cerebrovascular and cardiovascular diseases, diabetes mellitus, IBD, tuberculous anal fistula, malignancy, liver diseases, kidney diseases or mental illnesses were excluded from this study. BYD was administered twice daily for consecu- tive 2 weeks (after a meal in the morning and evening; n=100 ml for each). The components of BYD include astragalus (15 g), atractylodes (10 g), codonopsispilosula (15 g), angelica (6 g), dried tangerine (6 g), radix bupleuri (5 g), rattle- top (5 g) and prepared licorice root (5 g). They were under granule preparation, which was pro- duced with uniform technology, delivered by national pharmaceutical factory. They were concentrating agent of herb. Thus, the drug quality was guaranteed. These granules were purchased from JiangyinTianjiang Pharmaceu- tical Company and mixed in the Department of Pharmacy of Yueyang Hospital of Integrated Chinese and Western Medicine of Shanghai University of Traditional Chinese Medicine. Analysis of microbial diversity

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Original Article Retrospective analysis of corneal transplantation: a tertiary hospital database study over ten years

Original Article Retrospective analysis of corneal transplantation: a tertiary hospital database study over ten years

The indication for corneal transplantation varied from country to country, with the great- est variance between developing and devel- oped countries. Patients for corneal tran- splantation from America and Europe were mainly caused by corneal endothelium dystro- phy, pseudophakic bullous keratopathy and re-graft [2-5]. The indication of corneal trans- plantation in Australia was mostly due to kera- toconus, and then caused by re-graft and pseu- dophakic bullous keratopathy [5]. In Asia, corneal transplantation was mainly caused by infectious corneal diseases, ocular trauma scar and keratoconus [6]. Our study found that, simi- lar to other developing countries, the major indication of corneal transplantation in China were infectious corneal diseases/old kerato- leukoma (31.47%), and then re-graft (17.66%), ocular trauma (14.43%), and corneal endothe- lium decompensation (9.95%). Keratoleuko- ma (infectious and obsolete), which was the primary cause of corneal transplantation in this study, was common sequelae of corneal le- sions after corrupt the corneal stroma. Con- firmed infectious keratoleukoma was 106 eyes, accounting for 13.18% of total cases, with 18.58% infectious caused by virus. The Herpes simplex virus keratitis was the major cause of the blinding corneal disease globally, with char- Figure 4. Annually changing pattern for PKP & PKP+ and LK & LK+ (PKP:

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Measurement of W boson angular distributions in events with high transverse momentum jets at root s=8 TeV using the ATLAS detector

Measurement of W boson angular distributions in events with high transverse momentum jets at root s=8 TeV using the ATLAS detector

We acknowledge the support of ANPCyT, Argentina; YerPhI, Armenia; ARC, Australia; BMWFW and FWF, Austria; ANAS, Azerbaijan; SSTC, Belarus; CNPq and FAPESP, Brazil; NSERC, NRC and CFI, Canada; CERN; CONICYT, Chile; CAS, MOST and NSFC, China; COLCIENCIAS, Colombia; MSMT CR, MPO CR and VSC CR, Czech Republic; DNRF and DNSRC, Denmark; IN2P3-CNRS, CEA- DSM/IRFU, France; GNSF, Georgia; BMBF, HGF, and MPG, Germany; GSRT, Greece; RGC, Hong Kong SAR, China; ISF, I-CORE and Benoziyo Center, Israel; INFN, Italy; MEXT and JSPS, Japan; CNRST, Morocco; FOM and NWO, Netherlands; RCN, Norway; MNiSW and NCN, Poland; FCT, Por- tugal; MNE/IFA, Romania; MES of Russia and NRC KI, Russian Federation; JINR; MESTD, Serbia; MSSR, Slovakia; ARRS and MIZŠ, Slovenia; DST / NRF, South Africa; MINECO, Spain; SRC and Wallenberg Foundation, Sweden; SERI, SNSF and Cantons of Bern and Geneva, Switzerland; MOST, Taiwan; TAEK, Turkey; STFC, United Kingdom; DOE and NSF, United States of America. In addition, individual groups and members have received support from BCKDF, the Canada Council, CANARIE, CRC, Compute Canada, FQRNT, and the Ontario Innovation Trust, Canada; EPLANET, ERC, FP7, Ho- rizon 2020 and Marie Skłodowska-Curie Actions, European Union; Investissements d’Avenir Labex and Idex, ANR, Région Auvergne and Fondation Partager le Savoir, France; DFG and AvH Foundation, Ger- many; Herakleitos, Thales and Aristeia programmes co-financed by EU-ESF and the Greek NSRF; BSF, GIF and Minerva, Israel; BRF, Norway; Generalitat de Catalunya, Generalitat Valenciana, Spain; the Royal Society and Leverhulme Trust, United Kingdom.

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Original Article Factors affecting the outcome of hemi hip arthroplasty in elderly patients with femoral neck fractures

Original Article Factors affecting the outcome of hemi hip arthroplasty in elderly patients with femoral neck fractures

The morbidity of femoral neck fractures has increased in China. Although uncemented bipo- lar hemi hip arthroplasty has been widely used in clinical practice, the postoperative prognosis is not always satisfactory [1, 2]. The outcome of hemi hip arthroplasty is affected by many fac- tors such as the patients’ age, body mass index (BMI), and comorbidities. Inappropriate periop- erative management affects the patients’ post- operative rehabilitation. Therefore, treating fe- moral neck fractures in elderly patients should reduce the risk of surgery and meet the patients’ basic functional demands. Presently, many studies have only focused on the out- come of total hip arthroplasty because of osteoarthritis [3-5]. There is a lack of research related to femoral neck fractures in elderly patients with complex conditions treated by hemi hip arthroplasty.

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Original Article Relationship between angiotensinogen genetic polymorphism and glioma in Chinese population

Original Article Relationship between angiotensinogen genetic polymorphism and glioma in Chinese population

Glioma is one of the common intracranial tumors. Currently, the exact etiology and patho- genesis are not fully understood. Studies show that a variety of factors including environmen- tal and genetic factors are involved in its inci- dence and development [1-5]. Human angio- tensinogen (AGT), as one member of renin- angiotensin-aldosterone system (RAAS), not only is involved in regulating blood pressure and stabilizing fluid balance, but also can inhib- it tumor cell proliferation, migration and tumor vascularization [6-8]. AGT gene exon 2 has a point mutation, which can transform the No. 235 methionine (Met) into a threonine (Thr). Several studies have investigated the correla- tion between AGT M235T gene polymorphism and various tumors [9-11]. However, the asso- ciation of association of AGT M235T gene poly- morphism with glioma remains unclear. In this study, the polymerase chain reaction-restric- tion fragment length polymorphism (PCR-RFLP) was used to study the relationship between AGT M235T gene polymorphism and glioma in Chinese Han population, in order to provide a theoretical basis for further investigating the

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Original Article Application of a nomogram in detection of lymph node metastases in T1 colorectal cancer

Original Article Application of a nomogram in detection of lymph node metastases in T1 colorectal cancer

erative pathology with corre- sponding ICD-10 codes [ade- nocarcinoma (8010, 8020- 8022, 8140-8141, 8144- 8145, 8210-8211, 8220- 8221, 8230-8231, 8260- 8263), mucinous adenocarci- noma (8470, 8472-8473, 8480-8481), signet ring cell carcinoma (8490)]; and (3) complete medical data includ- ing the patient’s age and race, gender, marital status, tumor site, tumor size, differentia- tion, the status of lymph node involvement, and follow-up period data. The exclusion cri- teria included the following: (1) preoperative radiotherapy; (2) no cancer-directed surgery and local excision only; or (3) presence of non-first-tumors and synchronous distant me- tastases. This study was approved by the institutional ethics review board of Shanghai Electric Power Hospital, Shanghai, China. In total, 19,238 colorectal can- cer patients were eligible for analysis.

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Measurements of top-quark pair differential cross-sections in the e mu channel in pp collisions at root s=13 TeV using the ATLAS detector

Measurements of top-quark pair differential cross-sections in the e mu channel in pp collisions at root s=13 TeV using the ATLAS detector

We acknowledge the support of ANPCyT, Argentina; YerPhI, Armenia; ARC, Australia; BMWFW and FWF, Austria; ANAS, Azerbaijan; SSTC, Belarus; CNPq and FAPESP, Brazil; NSERC, NRC and CFI, Canada; CERN; CONICYT, Chile; CAS, MOST and NSFC, China; COLCIENCIAS, Colombia; MSMT CR, MPO CR and VSC CR, Czech Republic; DNRF and DNSRC, Denmark; IN2P3-CNRS, CEA-DSM/IRFU, France; SRNSF, Georgia; BMBF, HGF, and MPG, Germany; GSRT, Greece; RGC, Hong Kong SAR, China; ISF, I-CORE and Benoziyo Center, Israel; INFN, Italy; MEXT and JSPS, Ja- pan; CNRST, Morocco; NWO, Netherlands; RCN, Norway; MNiSW and NCN, Poland; FCT, Portugal; MNE/IFA, Romania; MES of Russia and NRC KI, Russian Federation; JINR; MESTD, Serbia; MSSR, Slovakia; ARRS and MIZŠ, Slovenia; DST/NRF, South Africa; MINECO, Spain; SRC and Wallen- berg Foundation, Sweden; SERI, SNSF and Cantons of Bern and Geneva, Switzerland; MOST, Taiwan; TAEK, Turkey; STFC, United Kingdom; DOE and NSF, United States of America. In addition, indi- vidual groups and members have received support from BCKDF, the Canada Council, CANARIE, CRC, Compute Canada, FQRNT, and the Ontario Innovation Trust, Canada; EPLANET, ERC, ERDF, FP7, Horizon 2020 and Marie Skłodowska-Curie Actions, European Union; Investissements d’Avenir Labex and Idex, ANR, Région Auvergne and Fondation Partager le Savoir, France; DFG and AvH Foundation, Germany; Herakleitos, Thales and Aristeia programmes co-financed by EU-ESF and the Greek NSRF; BSF, GIF and Minerva, Israel; BRF, Norway; CERCA Programme Generalitat de Catalunya, Generalitat Valenciana, Spain; the Royal Society and Leverhulme Trust, United Kingdom.

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Microbiological analysis of endotracheal aspirate and endotracheal tube cultures in mechanically ventilated patients

Microbiological analysis of endotracheal aspirate and endotracheal tube cultures in mechanically ventilated patients

Background: To compare the microbiological culture within endotracheal aspirate specimens (ETAs) and endotracheal tube specimens (ETTs) in patients undergoing mechanical ventilation (MV) by statistical tools. Method: ETAs and ETTs from a total number of 81 patients, who were undergoing MV at the intensive care unit (ICU) of Jiading Central Hospital Affiliated Shanghai University of Medicine & Health Sciences from September 1st, 2017 to August 31st, 2018, were collected for microbiological culture analysis. Correlation of ETAs and ETTs cultures were obtained by Spear-men correlation analysis, while the consistency of the two specimens was determined by Kappa analysis and principal component analysis (PCA).

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