Shh signaling pathway
Original Article Expression of Shh signaling pathway factors in gastrointestinal stromal tumor tissues and their associations with clinical pathological factors
... of Shh signaling pathway factors in Gastrointestinal stromal tumor (GIST) tissues and their associations with clinical pathological ...of Shh signaling pathway proteins ...
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RKIP reduction enhances radioresistance by activating the Shh signaling pathway in non-small-cell lung cancer
... Our research found that RKIP expression was elevated in NSCLC samples that were more sensitive to radiotherapy and that the silencing of RKIP could increase the radioresistance of cancer cells and could promote tumor ...
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Pancreatic stellate cells contribute pancreatic cancer pain via activation of sHH signaling pathway
... the sHH signaling pathway played a key role in the regulation of TRPV1 and pain factors (SP and ...the sHH signaling pathway are important for pancreatic ...
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Changes in the number of CD31<sup>−</sup>CD45<sup>−</sup>Sca-1<sup>+</sup> cells and Shh signaling pathway involvement in the lungs of mice with emphysema and relevant effects of acute adenovirus infection
... canonical Shh signaling pathway components, including Shh, Ptch1, Gli1, Gli2, and Gli3, were signifi- cantly reduced in patients with COPD compared to those in control smokers, which was ...
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Original Article Activation of SHH signaling pathway promotes vasculogenesis in post-myocardial ischemic-reperfusion injury
... in SHH signal on vasculogenesis during ...of SHH signal proteins expression on CMECs apoptosis and proliferation, as well as the deep ...of SHH on CMECs vasculogenesis in post-MIRI and to explore the ...
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The Sonic hedgehog pathway independently controls the patterning, proliferation and survival of neuroepithelial cells by regulating Gli activity
... Wnt signaling in promoting the proliferation and survival of neural progenitors at least in dorsal regions of the caudal neural tube (Dickinson et ...that Shh may also play a major ...to Shh ...
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Inhibition of SHH pathway mechanisms by arsenic trioxide in pediatric medulloblastomas: a comprehensive literature review.
... the SHH pathway is the mutation of inhibitory regulatory ...the SHH signaling pathway, the PTCH1 mutation seems to be sufficient for the development of ...that SHH ...
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Glucocorticoids and neonatal brain injury: the hedgehog connection
... (Shh) signaling pathway, a crucial regulator of brain devel- opment and neural stem/progenitor cells (see the related study beginning on page ...suppress Shh-induced proliferation of ...
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Sonic Hedgehog Pathway as the Prognostic Marker in Patients with Extensive Stage Small Cell Lung Cancer
... (Shh) signaling pathway is known to play a crucial role in carcinogenesis in various malignancies, in- cluding lung cancer regarding tumorigenesis, angiogenesis, and cellular ...of Shh ...
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Quantitative analyses link modulation of sonic hedgehog signaling to continuous variation in facial growth and shape
... enhance SHH-signaling activity (GLI3 and PTC, respectively) and phenotypic outcomes range from hypertelorism to midline clefts (Balk and Biesecker, ...the SHH- signaling pathway as a ...
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<p>Curcumin Affects Gastric Cancer Cell Migration, Invasion and Cytoskeletal Remodeling Through Gli1-β-Catenin</p>
... (Shh) signaling pathway plays an important role in embryonic development, adult tissue maintenance and ...18,19 Shh canonical signaling occurs when Shh binds to Ptch1, Smo ...
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Identification of COX5B as a novel biomarker in high-grade glioma patients
... KEGG pathway is a collection of manually drawn pathway maps representing our knowledge of the molecular interaction and reaction network for cellular processes, human diseases, and so ...
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Otic ablation of smoothened reveals direct and indirect requirements for Hedgehog signaling in inner ear development
... of Shh acting directly on the otic epithelium comes from the observation that Gli1, a transcriptional target of the Shh pathway, is expressed in a graded manner along the dorsoventral axis of the ...
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Combined detection of IL-6 and IL-8 is beneficial to the diagnosis of early stage esophageal squamous cell cancer: a preliminary study based on the screening of serum markers using protein chips
... The differentially expressed proteins were loaded into the DAVID 6.7 online server to annotate their functionality under the maximum false discovery rate of 0.05. The involved biological processes and signaling ...
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Brfl Post-Transcriptionally Regulates Pluripotency and Differentiation Responses Downstream of Erk MAP Kinase
... microRNA pathway, AUBPs are known regulators of splicing, mRNA stability, translational efficiency and RNA transport (68), and could provide an additional layer of developmental regulation that complements other ...
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Identification of key pathways and genes in <em>TP53 </em>mutation acute myeloid leukemia: evidence from bioinformatics analysis
... receptor signaling proteins, serine-threonine kinase activity, and protein tyrosine kinase ...MAPK signaling pathway and pathways in cancer (Figure ...
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SHH pathway inhibition is protumourigenic in adamantinomatous craniopharyngioma.
... the SHH pathway has been demonstrated in gene expression analyses of ACP (Holsken et ...the SHH pathway ...the SHH 315 pathway may be activated in a paracrine manner (Theunissen ...
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Autocrine Sonic hedgehog signaling promotes gastric cancer proliferation through induction of phospholipase Cγ1 and the ERK1/2 pathway
... The secreted SHH levels were detected by ELISA. One hundred microliters of cell supernatant was used for the SHH assay using an ELISA kit (Lifespan, BioSciences, USA). Briefly, a total of 100 μl per well of ...
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Original Article Pathway analysis of esophageal squamous cell carcinoma using iTRAQ-based quantitative proteomic approach
... Wnt signaling pathway was very important dur- ing the development of ...Wnt signaling pathway of ESCC were list- ed in the KEGG diagram with pathway ID ko04310 (Figure ...Wnt ...
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Identification of key gene pathways and coexpression networks of islets in human type 2 diabetes
... STRING database (http://string-db.org) was applied to develop DEG-encoded proteins and PPI network. Confi- dence score > 0.4 was set as significant. The PPI network was visualized by the Cytoscape software (Version ...
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