Si/sub 3/N/sub 4/:H
Immobilized transferrin Fe<sub>3</sub>O<sub>4</sub>@SiO<sub>2</sub> nanoparticle with high doxorubicin loading for dual-targeted tumor drug delivery
... DMP was suspended in 10 mL phosphate-buffered saline (PBS) solution, and incubated with 5 mg EDC and 5 mg NHS for 30 minutes at room temperature. Then, the products were separated using magnetic separation and ...
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The effect of magnetic nanoparticles of Fe<sub>3</sub>O<sub>4</sub> on immune function in normal ICR mice
... Nanotechnology offers an efficient alternative for cancer diagnostics and tumor target treatment due to the unique properties of nanostructures, such as large surface-to-volume ratio, porous structure, embedded effect, ...
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Effect of Fe<sub>3</sub>O<sub>4</sub>-magnetic nanoparticles on acute exercise enhanced KCNQ<sub>1</sub> expression in mouse cardiac muscle
... Forty-two mice were randomly assigned to either the non- exercised control group (n = 6) or exercise groups (n = 36). Thirty-six mice were placed into plastic cylinders (23 cm tall × 14 cm diameter) ...
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Biosafety evaluation of Janus Fe<sub>3</sub>O<sub>4</sub>-TiO<sub>2</sub> nanoparticles in Sprague Dawley rats after intravenous injection
... molecular weights. Immunoblots for expression of p38, p-p38, JNK, p-JNK, HO-1, ERK, c-Jun, cleaved caspase 3, Bcl2, Bax, P50, p53, Nrf2, Akt, and GAPDH were detected. All antibodies for Western blot in this study ...
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Daunorubicin-loaded magnetic nanoparticles of Fe<sub>3</sub>O<sub>4</sub> overcome multidrug resistance and induce apoptosis of K562-n/VCR cells <em>in vivo</em>
... MNPs-Fe 3 O 4 , which has no cytotox- icity to cells, is able to reverse ...Fe 3 O 4 fail to further suppress the growth of K562-n tumor ...
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Decreased bacteria activity on Si<sub>3</sub>N<sub>4</sub> surfaces compared with PEEK or titanium
... (Si 3 N 4 ) – were tested to understand their respective susceptibility to bacterial infection with Staphylococcus epidermidis, Staphlococcus aureus, Pseudomonas aeruginosa, Escherichia coli ...
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NH<sub>4</sub>HCO<sub>3</sub> gas-generating liposomal nanoparticle for photoacoustic imaging in breast cancer
... NH 4 HCO 3 solutions with regard to time ...NH 4 HCO 3 solution quickly reached a peak value and decreased soon ...NH 4 HCO 3 ...NH 4 HCO 3 decomposes into CO 2 , ...
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Effect of interaction of magnetic nanoparticles of Fe<sub>3</sub>O<sub>4</sub> and artesunate on apoptosis of K562 cells
... and the blots were stained with specific primary antibodies, including anti-bcl-2, anti-bax, anti-survivin, anti-bcl-rambo, anti-active caspase-3, and anti-GAPDH antibodies overnight at 4 ° C. Then, the ...
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Biocompatibility of magnetic Fe<sub>3</sub>O<sub>4</sub> nanoparticles and their cytotoxic effect on MCF-7 cells
... Fe 3 O 4 nano magnetofluid (0.5, 1.0, 1.5, and 2.0 g/L Fe 3 O 4 ), and a simple magnetic field irradiation group (a negative control group plus magnetic field ...and 4 kW with an output ...
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Preparation of Fe<sub>3</sub>O<sub>4</sub> magnetic nanoparticles coated with gallic acid for drug delivery
... All the materials used in this study were of analytical grade and required no further purification. Iron (II) chloride tetra- hydrate (FeCl 2 ⋅ 4H 2 O $ 99%) and iron (III) chloride hexahy- drate (FeCl 3 ⋅ 6H 2 O, ...
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Synthesis of composite magnetic nanoparticles Fe<sub>3</sub>O<sub>4</sub> with alendronate for osteoporosis treatment
... Fe 3 O 4 , Dex/Fe 3 O 4 , and Bis/Dex/Fe 3 O 4 was verified by XRD (Figure ...Fe 3 O 4 pattern published by ...Dex/Fe 3 O 4 and Bis/Dex/ Fe 3 O ...
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The changes of T lymphocytes and cytokines in ICR mice fed with Fe<sub>3</sub>O<sub>4</sub> magnetic nanoparticles
... Fe 3 O 4 magnetic nanoparticles (Fe 3 O 4 ...Fe 3 O 4 -MNPs were synthesized, and their characteristics such as particle size, zeta potential, and X-ray diffraction patterns were ...
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Magnetic Fe<sub>3</sub>O<sub>4</sub> nanoparticles and chemotherapy agents interact synergistically to induce apoptosis in lymphoma cells
... MNP-Fe 3 O 4 with different chemo- therapeutics may provide new clinical options in the treatment of ...MNP-Fe 3 O 4 with other compounds, eg, adriamycin, daunorubicin, and dexamethasone, all ...
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Fe<sub>3</sub>O<sub>4</sub>/Au magnetic nanoparticle amplification strategies for ultrasensitive electrochemical immunoassay of alfa-fetoprotein
... HAuCl 4 solution containing ...in 3% bovine serum albumin and phosphate-buffered solution at 37 ° C for one hour to block excess active groups and nonspecific binding sites on the ...
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Preparation and in vitro evaluation of doxorubicin-loaded Fe<sub>3</sub>O<sub>4</sub> magnetic nanoparticles modified with biocompatible copolymers
... Fe 3 O 4 -PLGA-PEG 2000 -doxorubicin has dose-dependent and time-dependent cytotoxicity against the A549 lung can- cer cell line (IC 50 ...Fe 3 O 4 -PLGA-PEG 3000 -doxorubicin has dose- ...
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Multifunctional magnetic Fe<sub>3</sub>O<sub>4</sub> nanoparticles combined with chemotherapy and hyperthermia to overcome multidrug resistance
... Fe 3 O 4 -MNP increased to ...Fe 3 O 4 -MNP- DNR-5-BrTet the temperature increased to ...Fe 3 O 4 -MNP throughout the ...Fe 3 O 4 -MNP or Fe 3 O 4 ...
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Magnetic nanoparticles of Fe<sub>3</sub>O<sub>4</sub> enhance docetaxel-induced prostate cancer cell death
... culture dishes; cells were either untreated (control), or treated with DTX (1 nM) or MgNPs-Fe 3 O 4 (10 µ g/mL or 100 µ g/mL) in the absence or presence of DTX (1 nM). Aspirated medium was collected to ...
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Fe<sub>3</sub>O<sub>4</sub>-based PLGA nanoparticles as MR contrast agents for the detection of thrombosis
... Fe 3 O 4 with a PLGA- and cRGD-based delivery system to synthesize NPs in this study did not increase ...within 3 h and returned to normal values after 24 h; we thus determined that, ...
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Biocompatibility of Fe<sub>3</sub>O<sub>4</sub>@Au composite magnetic nanoparticles in vitro and in vivo
... Fe 3 O 4 -MNPs was about 20 nm. After modification of the Fe 3 O 4 -MNPs with gold shell, the average diameter of the resulting core–shell Fe 3 O 4 @Au composite MNPs was about ...
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Pharmacokinetic parameters and tissue distribution of magnetic Fe<sub>3</sub>O<sub>4</sub> nanoparticles in mice
... Fe 3 O 4 MNPs in the various organs and tissues is shown in Figures 3 and ...Fe 3 O 4 MNPs at all time points between the experimental and control groups, there were statistically ...
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