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signaling systems

Phosphate sink containing two component signaling systems as tunable threshold devices

Phosphate sink containing two component signaling systems as tunable threshold devices

... biological systems and reengineer existing ...of signaling circuits hampered by limited understanding of their systems dynamics and experimental ...two-component signaling systems offer ...

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Mitochondrial Two-Component Signaling Systems in Candida albicans

Mitochondrial Two-Component Signaling Systems in Candida albicans

... These signaling cascades originated in prokaryotes and were inherited by eukaryotes via endosymbiotic lateral gene transfer from ancestral ...two-component signaling pathway that seem to be targeted to the ...

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Shared signaling systems in myeloid cell mediated muscle regeneration

Shared signaling systems in myeloid cell mediated muscle regeneration

... invaded injured muscle and expressed high levels of IL-4 following CTX injections into muscle (Heredia et al., 2013). Ablation of IL-4 expression slowed the recovery of normal muscle architecture (Heredia et al., 2013), ...

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Computer simulation: A new scientific approach to the study of language evolution

Computer simulation: A new scientific approach to the study of language evolution

... of signaling system evolution that would otherwise remain ...by signaling systems and the low-level behaviors of the individual signalers and receivers that constitute these ...

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Genotyping of Pseudomonas aeruginosa isolates from pulmonary infections in non-cystic fibrosis bronchiectasis patients

Genotyping of Pseudomonas aeruginosa isolates from pulmonary infections in non-cystic fibrosis bronchiectasis patients

... Comparative genomics of isolates of a Pseudomonas aeruginosa epidemic strain associated with chronic lung infections of cystic fibrosis patients... The multiple signaling systems regulat[r] ...

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Indian Railway: At a Glance

Indian Railway: At a Glance

... automatic signaling, construction of low height subways substituting level crossings, rail under bridges and over ...in signaling systems, the effects of freight traffic and human factors such as ...

5

Theoretical Foundations for Preference Representation in Systems Engineering

Theoretical Foundations for Preference Representation in Systems Engineering

... Tremendous cost growths associated with Major Defense Acquisition Programs (MDAPs) is a crucial problem posed to the Department of Defense (DoD). Although as of 2016, cost growth is significantly lower than historical ...

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Sustainable Feedbacks of Colombian Paramos Involving Livestock, Agricultural Activities, and Sustainable Development Goals of the Agenda 2030

Sustainable Feedbacks of Colombian Paramos Involving Livestock, Agricultural Activities, and Sustainable Development Goals of the Agenda 2030

... The work was executed taking as main reference the Páramo ecosystems of Colombia, almost all located on the Andes mountain range (Figure 2). It is estimated that about 300,000 to 500,000 people are currently populating ...

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Abstract: Drylands today are facing a landscape-scale water storage problem. Throughout the

Abstract: Drylands today are facing a landscape-scale water storage problem. Throughout the

... The occurrences of droughts and a general increase in aridity are drying upland soils, decreasing vegetation, and resulting in scouring floods across the American Southwest. The complexity and scale of ecosystems and ...

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Abstract: The operating landscape of 21st century systems is characteristically ambiguous,

Abstract: The operating landscape of 21st century systems is characteristically ambiguous,

... autonomous systems, their resources, and capabilities to enable new functionality, performance, and missions exceeding functions, performance, or mission of the individual constituent ...integrating systems ...

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Expression of protein-tyrosine phosphatases in Acute Myeloid Leukemia cells: FLT3 ITD sustains high levels of DUSP6 expression

Expression of protein-tyrosine phosphatases in Acute Myeloid Leukemia cells: FLT3 ITD sustains high levels of DUSP6 expression

... attenuated Dusp6 expression were, however, moderately impaired in proliferation, indicating that high DUSP6 levels may not play a negative but rather some positive role in FLT3 ITD dependent cell growth. Forced overex- ...

15

Brfl Post-Transcriptionally Regulates Pluripotency and Differentiation Responses Downstream of Erk MAP Kinase

Brfl Post-Transcriptionally Regulates Pluripotency and Differentiation Responses Downstream of Erk MAP Kinase

... AU-rich element mRNA binding proteins (AUBPs) represent an important class of regulators required for the proper development of embryonic and adult tissues in the mouse (66), but whether they have developmentally ...

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Nonclassical Systemics of Quasicoherence: From Formal Properties to Representations of Generative Mechanisms. A Conceptual Introduction to a Paradigm-Shift

Nonclassical Systemics of Quasicoherence: From Formal Properties to Representations of Generative Mechanisms. A Conceptual Introduction to a Paradigm-Shift

... complex systems such as collective behaviors, ...with systems whose components are in large numbers (potentially tending to infinity), mutating and unstable; and when coherences occur in a nonconstant way ...

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Production Strategy Development: Simulation of Dependencies Using Recurrent Fuzzy Systems

Production Strategy Development: Simulation of Dependencies Using Recurrent Fuzzy Systems

... The aim of this paper is to present a method for the efficient development of production strategies in Africa, based on a recurrent fuzzy system. For this purpose, the theoretical background of production strategies, ...

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Dominant Factors for an Eective Selection System: An Australian Education Sector Perspective

Dominant Factors for an Eective Selection System: An Australian Education Sector Perspective

... In more recent times, with the advancements in IT, several applications of technologies in the selection processes are also being upgraded using artificial intelligence. This is necessary due to the uncertainty and ...

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Application of Model-Based Systems Engineering Concepts to Support Mission Engineering

Application of Model-Based Systems Engineering Concepts to Support Mission Engineering

... the Systems Modeling Language ...end systems engineering ...Oriented Systems Engineering, IBM Harmony for Systems Engineering, Vitech Corporation’s Model-Based Systems Engineering ...

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The Rural-Urban Food Systems’ Links with the Agenda 2030: From FAO Guidelines on Food Supply and Distribution Systems to a Dairy Sector Application in the Area of Bogota

The Rural-Urban Food Systems’ Links with the Agenda 2030: From FAO Guidelines on Food Supply and Distribution Systems to a Dairy Sector Application in the Area of Bogota

... food systems aimed to minimize food gaps have to be indirectly obtained by tuning the policies applied in other sectors (land use, road logistics, job dynamics, urban dynamics, resource use efficiency, health, ...

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Developing a Systems Architecture Model to Study the Science, Technology and Innovation in International Studies

Developing a Systems Architecture Model to Study the Science, Technology and Innovation in International Studies

... the Systems Architecture Model, responds to the conceptual and practical difficulties of the description and the study of complex systems like the international system ...

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Circular Economy for Food: A Systemic Interpretation of 40 Case Histories in the Food System in Their Relationships with SDGs

Circular Economy for Food: A Systemic Interpretation of 40 Case Histories in the Food System in Their Relationships with SDGs

... As we state in the introduction, food can embody the principles of the circular economy, but it can also provide support to identifying a track for its theoretical-practical evolution and in adjusting its goals ...

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Abstract: Developing causal loop diagrams (CLDs) involves identifying stakeholders and endogenous

Abstract: Developing causal loop diagrams (CLDs) involves identifying stakeholders and endogenous

... First, modellers and/or stakeholders must identify variables into endogenous (arising from within) and exogenous variables (beyond the system) [2]. Exogenous variables are important considerations to understanding a ...

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