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sIL-2R

Fulminant hepatitis and elevated levels of sIL-2R in thyroid storm

Fulminant hepatitis and elevated levels of sIL-2R in thyroid storm

... We report the case of a 48-year-old man with thyroid storm associated with fulminant hepatitis and elevated levels of soluble interleukin-2 receptor (sIL-2R). Fatigue, low-grade fever, shortness of breath, ...

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Original Article The plasma level of soluble IL-2 receptor (sIL-2R) is elevated in children with acute Kawasaki disease

Original Article The plasma level of soluble IL-2 receptor (sIL-2R) is elevated in children with acute Kawasaki disease

... of sIL-2R in patients with acute KD, but also the relation- ship between sIL-2R, Tregs and the IL-2/STAT5 signaling ...of sIL- 2R and IL-2/IL-2Rβ/STAT5 ...

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Interferon Gamma (IFN-γ) and Soluble Interleukin-2 Receptor (sIL-2R): Combined Diagnostic Markers of Tuberculous Pleural Effusion

Interferon Gamma (IFN-γ) and Soluble Interleukin-2 Receptor (sIL-2R): Combined Diagnostic Markers of Tuberculous Pleural Effusion

... and sIL-2R measurements have been evaluated individually in the diagnosis of pleural TB, obtained results for all three markers together in the same patient to improve the diagnostic efficacy of tuberculous ...

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A predictive tool for an effective use of 18F-FDG PET in assessing activity of sarcoidosis

A predictive tool for an effective use of 18F-FDG PET in assessing activity of sarcoidosis

... positive sIL-2R result alone (8 points; positive predictive value ...normal sIL-2R level, PET appeared only to be indicated in those with a total HRCT score of <6 points (positive ...

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Antenatal corticosteroids impact the inflammatory rather than the antiangiogenic profile of women with preeclampsia

Antenatal corticosteroids impact the inflammatory rather than the antiangiogenic profile of women with preeclampsia

... We found that, in sPE and spPE, the maternal circulatory levels of ET-1 are increased. Our findings that steroid treat- ment was associated with an increase in the maternal serum concentration of ET-1 despite the overall ...

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Age-Dependent Levels of Select Immunological Mediators in Sera of Healthy Children

Age-Dependent Levels of Select Immunological Mediators in Sera of Healthy Children

... The detection of cytokines and soluble immunological re- ceptors in sera bears diagnostic relevance in many diseases. In specialized diagnostics, the evaluation of cytokine profiles can improve medical care and ...

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Elevated circulating soluble interleukin-2 receptor in patients with chronic liver diseases is associated with non-classical monocytes

Elevated circulating soluble interleukin-2 receptor in patients with chronic liver diseases is associated with non-classical monocytes

... between sIL-2R and (non- classical) monocytes raises the possibility that sIL-2R could serve as a surrogate marker for monocyte subset ...with sIL-2R, further indicating that ...

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Clinical significance of serum 2,5-oligoadenylate synthetase and soluble interleukin-2 receptor in hemophiliacs positive and negative for human immunodeficiency virus type 1.

Clinical significance of serum 2,5-oligoadenylate synthetase and soluble interleukin-2 receptor in hemophiliacs positive and negative for human immunodeficiency virus type 1.

... We measured serum 2,5-oligoadenylate synthetase (2,5-AS) levels and soluble interleukin-2 receptor (sIL-2R) levels in human immune deficiency virus type 1 (HIV-1)-positive and HIV-1-nega[r] ...

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Altered expression of inflammatory cytokines in primary osteoarthritis by human T lymphotropic virus type I retrovirus infection: a cross sectional study

Altered expression of inflammatory cytokines in primary osteoarthritis by human T lymphotropic virus type I retrovirus infection: a cross sectional study

... PTHrP, sIL-2R and IL-6 concentrations in SF positive for IgM antibody against HTLV-I antigen, a marker of persistent viral replication, were higher than of IgM-negative ...

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Increased soluble IL-2 receptor levels in serum from a patient with painless thyroiditis

Increased soluble IL-2 receptor levels in serum from a patient with painless thyroiditis

... serum sIL-2R likely increases as a result of T cell activation ...of sIL-2R in patients with refractory Graves ’ disease ...serum sIL-2R, even in the absence of autoimmune ...

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Evaluation of the immunomodulatory effects of a South African commercial traditional immune booster in human peripheral blood mononuclear cells

Evaluation of the immunomodulatory effects of a South African commercial traditional immune booster in human peripheral blood mononuclear cells

... ranging from 100 to 10 μg/mL were shown to stimulate the secretion of pro-inflammatory cytokines and increase sIL-2R levels in immunosuppressed and PHA-treated PBMCs (Figs. 2 and 3). However, this product ...

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Electrospun Silybin Enriched Scaffolds of Polyethylene Oxide as Wound Dressings: Enhanced Wound Closure, Reepithelization in Rat Excisional Wound Model

Electrospun Silybin Enriched Scaffolds of Polyethylene Oxide as Wound Dressings: Enhanced Wound Closure, Reepithelization in Rat Excisional Wound Model

... iodine), SIL loaded nanofibrous scaffolds (SIL-NF3), plain nanofibrous scaffolds (NF-P), respectively and the wounds were wrapped with surgical bandage to keep the scaffolds in ...

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Differential effects of locally and systemically administered soluble glycoprotein 130 on pain and inflammation in experimental arthritis

Differential effects of locally and systemically administered soluble glycoprotein 130 on pain and inflammation in experimental arthritis

... dose ratio between i.a.- and i.p.-applied sgp130 was per- formed according to the same criteria as for etanercept in previous studies, where systemic application showed a beneficial effect [17], we cannot completely ...

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Molecular Epidemiology of sil Locus in Clinical Streptococcus pyogenes Strains

Molecular Epidemiology of sil Locus in Clinical Streptococcus pyogenes Strains

... the sil locus, composed of six genes encoding a quorum-sensing complex, gives rise to a highly inva- sive ...that sil prevalence is around 15%; fur- thermore, whereas a correlation between the presence of ...

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Therapeutic effects of bone marrow-derived mononuclear cells from healthy or silicotic donors on recipient silicosis mice

Therapeutic effects of bone marrow-derived mononuclear cells from healthy or silicotic donors on recipient silicosis mice

... An increase in IL-1β levels might stimulate epithelial- mesenchymal transition and myofibroblast activation through a TGF-β1-mediated mechanism, thus leading to lung fibrosis [29]. The fibrotic process involves modified ...

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Teoretična odvisnost sil od geometrije pri obodnem frezanju

Teoretična odvisnost sil od geometrije pri obodnem frezanju

... določanje sil, mo­ m entov in moči, ta veličina p ri natančnem raču­ n an ju nim a nobenega ...določitve sil. Vsa n ad aljn ja izvajanja so zato usm erjena le v do­ ločanje sil, mom entov in moči — ...

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Current dynamic of nivation hollows in the Alto Sil (Cantabrian Mountain)

Current dynamic of nivation hollows in the Alto Sil (Cantabrian Mountain)

... RESUMEN: Entre los años 2003 y 2009 se ha realizado un seguimiento de los neveros más persistentes de un sector de la Cordillera Cantábrica, el Alto Sil. Este trabajo ha permitido localizar 8 nichos de nivación ...

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Association of Src-Related Kinase Lyn with the Interleukin-2 Receptor and Its Role in Maintaining Constitutive Phosphorylation of JAK/STAT in Human T-Cell Leukemia Virus Type 1-Transformed T Cells

Association of Src-Related Kinase Lyn with the Interleukin-2 Receptor and Its Role in Maintaining Constitutive Phosphorylation of JAK/STAT in Human T-Cell Leukemia Virus Type 1-Transformed T Cells

... We next determined whether Lyn interacts with components of the IL-2R signaling pathway in HTLV-1-infected cell lines. Our reasoning for suspecting this involvement was based on known associations of Lyn with ...

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X-linked severe combined immunodeficiency disease and the gamma c receptor component: prospects for molecular diagnosis.

X-linked severe combined immunodeficiency disease and the gamma c receptor component: prospects for molecular diagnosis.

... When the cDNA for the IL-2R b chain was cloned and isolated IL-2R b chains were expressed on the membranes of nonlymphoid cells, they were unable to bind IL-2 (11, 25, 38, 54). This suggested that a third ...

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The preclinical pharmacology of the high affinity anti IL 6R Nanobody® ALX 0061 supports its clinical development in rheumatoid arthritis

The preclinical pharmacology of the high affinity anti IL 6R Nanobody® ALX 0061 supports its clinical development in rheumatoid arthritis

... Compound-binding properties, such as affinity, and biological activity next to target selectivity contribute to the highly specific and competitive profile of therapeutic antibodies. ALX-0061 was purposely designed as a ...

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