single nucleotide polymorphism (SNP) array
Genetic Aberrations In Childhood Acute Lymphoblastic Leukaemia (All): Application Of High-Density Single Nucleotide Polymorphism Array (SNPA)
... Within the past year, new computer software tools have been developed by Affymetrix for data analysis of SNPA; these tools provide better and easier interpretation of results when compared with the manipulation of SNPA ...
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Comparative study of single-nucleotide polymorphism array and next generation sequencing based strategies on triploid identification in preimplantation genetic diagnosis and screen
... SNP array karotype to validate using NGS. The 9 triploid SNP array kayotype were shown in Supplementary Figure 1, one was amplification failure in our ...
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Characterization of polyploid wheat genomic diversity using a high-density 90000 single nucleotide polymorphism array
... intervarietal polymorphism with sequence variation that distinguished between the hybridization sites on the different genomes to which the SNP detection probes were predicted to hybridize (Table ...show ...
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Evaluation of single nucleotide polymorphism imputation using random forests
... haplotype data nor LD block data were used. Standard quality control was applied to genotype data of the Affymetrix GeneChip® Human Mapping 500k Array Set (488,146 SNPs) as recommended [1,2,4,13]. SNPs with a call ...
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Detection of three closely located single nucleotide polymorphisms in the EAAT2 promoter: Comparison of single strand conformational polymorphism (SSCP), pyrosequencing and Sanger sequencing
... capillary array electrophoresis technology) [6]. Due to these drawbacks single-strand conformation polymorphism (SSCP) is still very frequently used across many different fields for SNP detection ...
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A High-Density Linkage Map of the Ancestral Diploid Strawberry, Fragaria iinumae, Constructed with Single Nucleotide Polymorphism Markers from the IStraw90 Array and Genotyping by Sequencing
... of single nucleotide polymorphism (SNP) genotyping: the IStraw90 Array (hereafter “Array”), and genotyping by sequencing ...the Array and 893 from ...
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A genetic study and meta-analysis of the genetic predisposition of prostate cancer in a Chinese population
... performed single-nucleotide polymorphism (SNP) array analysis on a cohort of Chinese cases and controls and then meta-analysis with data from the existing Chinese prostate cancer genome-wide ...
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Usefulness of Single Nucleotide Polymorphism Data for Estimating Population Parameters
... gration, selection, and other factors. Many researchers This parameter is estimated using the Metropolis-Has- have recently begun collecting single nucleotide poly- tings method of Kuhner et al. (1995), ...
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Association between neonatal resuscitation and a single nucleotide polymorphism rs1835740
... Aim: The aim of this work is to test if three single nucleotide polymorphisms (SNPs) implicated in glutamate homeostasis or signalling and cellular survival are associated with birth condition. Methods: ...
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Frequency of M287T/AS3MT Single Nucleotide Polymorphism in an Iranian Population
... either single agent or in combination with ATRA for successful treatment of Acute Promyelocytic Leukemia (APL) ...this polymorphism, characterization of AS3MT gene and the utilization of pharmacokinetic ...
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New techniques to detect genomic variation
... This thesis outlines the rapid development of molecular techniques for detecting genomic variation. It describes advantages and disadvantages of specific techniques, and shows their application in the search for ...
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Functional Characterization of the OPRM1 A118G Single Nucleotide Polymorphism in Mice
... A single nucleotide polymorphism (SNP) in exon 1 of the µ-opioid receptor gene (OPRM1), in which an adenine to guanine substitution (A118G) exchanges an asparagine for an aspartic acid at a putative ...
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Reconstituting the Frequency Spectrum of Ascertained Single-Nucleotide Polymorphism Data
... Assume that we know the panel depth for both ascer- tainment experiments and that the discovery panel is part of the sample used to obtain the frequency spec- trum (as in case 1).. Furth[r] ...
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Computational Analysis of Single Nucleotide Polymorphism (SNPs) in HumanSLC5A1 Gene
... Abstract: Glucose galactose malabsorption (GGM) is an autosomal recessive disease manifesting within the first weeks of life. It is characterized by a selective failure to absorb dietary glucose and galactose from the ...
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Comparison of tagging single nucleotide polymorphism methods in association analyses
... We examined five regions known to harbor genetic asso- ciations in a small, well characterized sample [7]. SNPs in these chromosomes 5, 6, 20, and 21 regions were associ- ated with lymphocyte expression levels of ...
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A functional single nucleotide polymorphism of SET8 is prognostic for breast cancer
... RFLP-PCR was used to identify the genotypes of the SET8 (rs16917496 C/T) polymorphism within the 3′- UTR in patients and breast cancer cells. The amplification conditions were: 95°C for 5 min, 35 cycles of 95°C ...
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A common polymorphism near the interleukin-6 gene modifies the association between dietary fat intake and insulin sensitivity
... Background: Increasing evidence suggests a role for inflammation in the development of type 2 diabetes. Elevated levels of inflammatory cytokines, including interleukin-6, have been associ- ated with insulin resistance, ...
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Genetic evidence linking lung cancer and COPD: a new perspective
... of single nucleotide polymorphism associations in COPD and lung cancer to develop risk models may offer very important clinical utilities in risk prediction and risk stratification to enhance early ...
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The impact of single nucleotide polymorphism selection on prediction of genomewide breeding values
... The study focuses on the impact of different sets of single nucleotide polymorphisms (SNPs) selected from the available data set on prediction of genomewide breeding values (GBVs) of animals. Correlations ...
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Association of Osteopontin Gene Single Nucleotide Polymorphism with Systemic Lupus Erythematosus.
... gene polymorphism with systemic lupus erythematosus. A single nucleotide polymorphism (SNP) at position 9250 with replacement of C by T in exon 7 of the OPN gene (OPN gene 9250) is newly ...
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