Site-specific post-translational modification
PTM-ssMP: A Web Server for Predicting Different Types of Post-translational Modification Sites Using Novel Site-specific Modification Profile
... PTM site prediction because the local sequence of the PTM site is generally conserved ...ubiquitination site prediction server which build prediction model using feature extraction method based on ...
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Post translational modification of Parkin
... Post-translational modification of proteins by small ubiqui- tin like modifiers (SUMO) or in general SUMOylation is still not fully unravelled, though holds the indications that like ubiquitination ...
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Ubiquitination of HTLV I Tax in response to DNA damage regulates nuclear complex formation and nuclear export
... with specific cellular proteins is controlled, in part, by post-translational ...their modification status and/or interactions with host cell ...and post-translational modifica- ...
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Post-translational modification-regulated leukocyte adhesion and migration
... infection site to maximise their antigen uptake capacity ...antigen- specific T cells in the lymph nodes cease migration upon contact with antigen-presenting dendritic cells, forming a stable immunological ...
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Epigenetic marking of sperm by post-translational modification of histones and protamines
... methylation site, two acetyl- ation sites together, and two acetylation and one methylation sites (Figure 5B and C, and [see Additional file 3: Figure ...of specific fragment ...
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Surf the Post-translational Modification Network of p53 Regulation
... individual modification and a specific ...one site exerts various effects in different con- texts and under different stresses, even if the effects are seemingly ...
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Post-translational modification of Rauscher leukemia virus precursor polyproteins encoded by the gag gene.
... JLS-V9 cells 51 chronically infected with R-MuLV and SC-1 wild mouse cell cultures 13 producing MCF murine virus 14, originally received from Janet Hartley National Cancer Institute, Bet[r] ...
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Microcystin-LR (MCLR) Induces a Compensation of PP2A Activity Mediated by α4 Protein in HEK293 Cells
... PP2A activity was measured by two methods, both determine the amount of free phosphate by measuring the absorbance of a molybdate: malachite green: phosphate complex. First was with a ser- ine/threonine phosphatase assay ...
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POST-TRANSLATIONAL MODIFICATION OF XANTHINE DEHYDROGENASE IN A NATURAL POPULATION OF DROSOPHILA MELANOGASTER
... We are thus presented with a view of genetic variation for the xanthine dehydrogenase locus that encompasses both a high degree of structural gene heterozygosity (previously repor[r] ...
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The pupylation pathway and its role in mycobacteria
... The post-translational modification Pup that recruits proteins for degradation by bacterial proteasomes is functionally related to the eukaryotic ubiquitin (Ub) tag without showing any sequence or ...
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DNA methylation and histone post-translational modification stability in post-mortem brain tissue
... immunohistochemistry allows regional and subcellular evaluation of antibody binding patterns. Isolation of nuclei from frozen preceded Western blotting; the histone purifi- cation procedures might be associated with some ...
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Regulation of liver mitochondrial metabolism during hibernation by post-translational modification
... phosphorylation is not enzyme-catalyzed and apparently involves non-covalent bonds, which may represent a way by which mitochondrial metabolism can be regulated in response to intramitochondrial energy status since free ...
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Epigenetic mechanisms in cancer: push and pull between kneaded erasers and fate writers
... Improving the bioavailability and delivery of synthetic compounds and natural products to the target site is a rapidly growing area of research. Accumulating evidence shows that nanotechnological delivery has been ...
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Epigenetic modifications in rheumatoid arthritis
... histone modification around the promoter region of the mir-127 gene by 5-AZA and PBA treatment restored miR-127 expression in cancer cells with subsequent suppression of the proto-oncogene BCL6 ...
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A Fast and Quantitative Method for Post-translational Modification and Variant Enabled Mapping of Peptides to Genomes.
... Figure 8. Schematic of mapping visualization and color coding. (A) In the standard BED output file, peptides mapping to an exon are shown as single blocks (left), while peptides mapping across multiple exons highlight ...
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Predicting the pathway involved in post-translational modification of Elongation factor P in a subset of bacterial species
... EF-P modification pathway that was lost in specific phyla or if it appeared later on, as for example in the proteobacteria ancestor, and then was horizontally transferred in other ...
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Detection and analysis of disease-associated single nucleotide polymorphism influencing post-translational modification
... Post-translational modification (PTM) plays a crucial role in biological functions and corresponding disease developments. Discovering disease-associated non-synonymous SNPs (nsSNPs) altering PTM ...
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Targeting the SUMO pathway for neuroprotection in brain ischaemia
... Brain ischaemia is a complex pathological process that involves many signalling path- ways. Traditionally, single signalling pathways or functional processes have been explored as targets for therapeutic strategies that ...
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A STUDY ON THE ROLE OF DIETARY AGENT MOMORDICA CHARANTIA L ON PROTEIN GLYCATION
... spontaneous post translational modification of proteins by excess sugars causing formation of advanced glycation end products (AGEs) in diabetic individuals and responsible for diabetes ...pinpoint ...
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The Effects of Extreme Media on Political Behavior, Attitudes, and Media Selection
... In conjunction with the mechanistic study, we developed a chemical biology strategy for facile labeling and detection of substrates of MOF enzyme at cellular level. In this approach, a panel of Ac‐CoA analogs conjugated ...
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