Skeletal muscle function
Characterization and utilization of the flexor digitorum brevis for assessing skeletal muscle function
... assess skeletal muscle function and delineate regulatory mechanisms is essential to uncovering therapeutic approaches that preserve functional independence in a disease ...state. Skeletal ...
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Poloxomer 188 Has a Deleterious Effect on Dystrophic Skeletal Muscle Function
... fatal muscle wasting disease for which there is currently no cure and limited palliative ...cardiac muscle function, the effects of P188 on dystrophic skeletal muscle function ...
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Dietary and exercise manipulation of skeletal muscle function in older humans
... Analysis of body composition is a way to measure skeletal muscle mass. Body composition allows for the measurement of different body compartments based on the physical properties of the particular body ...
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25-hydroxyvitamin D3 and 1,25-dihydroxyvitamin D3 exert distinct effects on human skeletal muscle function and gene expression
... S1 Table. Bivariate correlations between serum 25OHD3 and gene expression in skeletal muscle. VDR = Vitamin D Receptor, RXRG = Retinoid X Receptor, Gamma; PPARD = Perox- isome Proliferator Activated ...
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Testing of therapies in a novel nebulin nemaline myopathy model demonstrate a lack of efficacy
... improve skeletal muscle perform- ance in our neb −/− ...increase skeletal muscle ...improve skeletal muscle ...facial muscle structure in neb −/− zebrafish, and observed ...
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Modifying function and fibrosis of cardiac and skeletal muscle from mdx mice
... and skeletal muscle function in mdx ...improving skeletal muscle function or ...cardiac function and coronary flow ...
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The effects of obesity on skeletal muscle contractile function
... isolated skeletal muscle function (Table 1) can enhance understanding of the mechanisms underpinning altered in vivo muscle ...isolated skeletal muscle approach permits direct ...
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Mitochondrial content is preserved throughout disease progression in the mdx mouse model of Duchenne muscular dystrophy, regardless of taurine supplementation
... taurine synthesis improves skeletal muscle function in the mdx mouse model for Duchenne muscular 587. dystrophy[r] ...
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A Longitudinal, Integrated, Clinical, Histological and mRNA Profiling Study of Resistance Exercise in Myositis
... decreasing muscle fibrosis, not only by suppressing the synthesis of collagen and other ECM components, but also by increasing col- lagenolysis and elastolysis by matrix metalloproteinases, such as matrix metal- ...
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The mitochondrial calcium uniporter underlies metabolic fuel preference in skeletal muscle
... For muscle fatigue experiments, mice were anesthetized with an intraperitoneal injection of pentobarbital, a midline incision running from the ankle to the thigh was created, and the skin and fascia were gently ...
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Molecules in motion: influences of diffusion on metabolic structure and function in skeletal muscle
... dark muscle from a variety of swimming and non-swimming crabs are generally applicable and independent of ...white muscle from black sea bass (Centropristis striata), suggesting that these subcellular ...
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Skeletal muscle expression and abnormal function of beta myosin in hypertrophic cardiomyopathy
... in skeletal muscle of hypertrophic cardiomyopathy ...in skeletal muscle by Western blot analysis, translocated actin filaments slower than normal controls in an in vitro motility ...
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Modifying function and fibrosis of cardiac and skeletal muscle from mdx mice
... vascular function (Mane et ...hastens muscle degeneration (Anderson & Vargas ...If muscle fibres express sufficient levels of nNOS, elevated l-arginine concentrations could augment NO synthesis ...
251
Skeletal muscle mechanics, energetics and plasticity
... in muscle architectures in individuals with spastic ...include: muscle size, muscle belly length, fascicle length, sarcomere length, and pennation ...of muscle mass in stroke survivors and ...
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MEF2: a central regulator of diverse developmental programs
... Recently, MEF2 proteins were shown to be necessary and sufficient to drive chondrocyte hypertrophy (Arnold et al., 2007) (Fig. 7A). Interestingly, this function of MEF2 is tightly regulated by the opposing ...
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Repairing skeletal muscle: regenerative potential of skeletal muscle stem cells
... Skeletal muscle damaged by injury or by degenerative diseases such as muscular dystrophy is able to regenerate new muscle ...the muscle fiber ...
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A Review of Maximizing Muscle Building Capabilities with Anabolic Enzymes
... of muscle building is through the direct manipulation of the intracellular enzymes that play key roles in the chemical reactions that lead to muscle ...other muscle building variables that are ...
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Crossroads between peripheral atherosclerosis, western-type diet and skeletal muscle pathophysiology: emphasis on apolipoprotein E deficiency and peripheral arterial disease
... to skeletal muscle due to ApoE deficiency, but mechanistic insights remain to be established and validated in future ...the muscle as compared with wild type mice ...the skeletal muscle ...
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Redox regulation of muscle adaptations to contractile activity and aging
... function that occurs with aging and the accelerated loss of skeletal muscle fibers in SOD1KO mice.. may be caused by superoxide toxicity 38, 56.[r] ...
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STIM1 as a key regulator for Ca2+ homeostasis in skeletal-muscle development and function
... loaded with Ca 2+ underpins the fast kinetics (Figure 2). The pre-localization of STIM1 in the SR at triad junctions was observed in differentiated myotubes of the C2C12 cell line as well as in native skeletal ...
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