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Skin wounds

Evaluation of matricellular proteins as potential therapeutics for the treatment of human chronic skin wounds

Evaluation of matricellular proteins as potential therapeutics for the treatment of human chronic skin wounds

... myofibroblast differentiation, where deletion of osteopontin attenuates TGFβ-dependent increases in α-SMA and ED-A FN expression (Lenga et al., 2008). CCN2 (further discussed below) promotes myofibroblast differentiation ...

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Comparison of Purse String Versus Conventional Closure of Ileostomy Skin Wounds

Comparison of Purse String Versus Conventional Closure of Ileostomy Skin Wounds

... Abstract- Background- Ileostomy closure is common surgical procedure done in most center across the globe. The aim of the study was to compare the purse string(PS) versus conventional linear closure(CLC) of ileostomy ...

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A porcine model for pathomorphological age assessment of surgically excised skin wounds

A porcine model for pathomorphological age assessment of surgically excised skin wounds

... of skin wounds in pigs is often requested in veterinary forensic pathology [1, ...2]. Wounds in pigs are primarily caused by external trauma, and the age of wounds submitted for forensic ...

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Computational analysis identifies putative prognostic biomarkers of pathological scarring in skin wounds

Computational analysis identifies putative prognostic biomarkers of pathological scarring in skin wounds

... by skin cells, such as keratinocytes and fibroblasts [45, ...and skin fibro- sis [39, 40]. Therefore, high levels of TIMP-1 in skin wounds are also likely to be predictive of pathological ...

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Immunohistological changes in skin wounds during the early periods of healing in a rat model

Immunohistological changes in skin wounds during the early periods of healing in a rat model

... Figure 1. Basic staining of skin wounds 2, 6, and 14 days after surgery. Day 2: thickness of cut edge of the epidermis (E) and beginning of cell proliferation and migration beneath the demarcation line ...

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Topical haemostatic agents for skin wounds: a systematic review

Topical haemostatic agents for skin wounds: a systematic review

... Haemostatic agents are particularly useful for patients requiring larger split skin graft harvests, burn wound deb- ridement, or for other reasons why minimisation of (topi- cal) blood loss is desired. According ...

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Effect of nanostructured extract morinda  citrofolia l. (noni) in infected wounds in rats

Effect of nanostructured extract morinda citrofolia l. (noni) in infected wounds in rats

... activity due to the phenolic compounds (anthraquinones) exist in the noni fruit. Thus, the effects of these compounds have been shown to have a direct effect in reversing the natural resistance of some bacteria to the ...

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A REVIEW ON ALOE VERA-THE WONDER MEDICINAL PLANT

A REVIEW ON ALOE VERA-THE WONDER MEDICINAL PLANT

... of skin wounds indicating the role of Aloe vera treatment in accelerating expression of vascular endothelial growth factor (VEGF) and TGF β-1 (stimulates fibroblasts to better reconstruct the extracellular ...

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Delayed wound repair and impaired angiogenesis in mice lacking syndecan 4

Delayed wound repair and impaired angiogenesis in mice lacking syndecan 4

... the syndecan-4 gene was disrupted by homologous recombination in embryonic stem cells to test the hypothesis that syndecan-4 contributes to wound repair. Mice heterozygous or homozygous for the disrupted syndecan-4 gene ...

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New Technique for Reconstructing Fresh Massive Wounds with Skin Flaps in Equine

New Technique for Reconstructing Fresh Massive Wounds with Skin Flaps in Equine

... equine skin injuries, including those with significant tissue loss, can be successfully managed with proper ...massive skin wounds has passed through many major key-points both in fixation material ...

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INVESTIGATION OF WOUND HEALING ACTIVITY OF LINSEED OIL (LINUM USITATISSIMUM) IN ANTISEPTIC CREAM

INVESTIGATION OF WOUND HEALING ACTIVITY OF LINSEED OIL (LINUM USITATISSIMUM) IN ANTISEPTIC CREAM

... damage. Wounds make the disorder the tissue integrity and loss of cellular level biological activity of living ...the skin is broken, or as a preventive measure before piercing the skin ...the ...

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Complex pediatric wound care with a dedicated pediatric wound care service: a review of our 12-year experience

Complex pediatric wound care with a dedicated pediatric wound care service: a review of our 12-year experience

... and/or follow-up emergency department visit; avoidance of an operating room visit when feasible; and avoidance of a prolonged hospital stay for pain management of wounds that require multiple dressing changes and ...

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Altered wound healing in mice lacking a functional osteopontin gene (spp1)

Altered wound healing in mice lacking a functional osteopontin gene (spp1)

... Immunostaining for OPN was performed with purified goat IgG of an antibody generated against rat OPN, OP199 (25). Antibody was used at a concentration of 10–18 m g/ml. Detection was done using either a ...

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A STUDY OF WOUND INFECTIONS AND MICROBIAL WOUND ISOLATES AT PRINCE SAUD BIN JALAWI HOSPITAL, SAUDI ARABIA

A STUDY OF WOUND INFECTIONS AND MICROBIAL WOUND ISOLATES AT PRINCE SAUD BIN JALAWI HOSPITAL, SAUDI ARABIA

... Introduction: The wound is a breach in the integrity of skin that leads to subcutaneous tissue exposure. Wound infection is one of the principal cause of patient morbidity and mortality. They are also considered ...

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COMPERATIVE EFFICACY OF THREE INDIGENOUS MEDICINAL PLANTS (TURMERIC, GARLIC, AND ALOE) WITH LOCALLY AVAILABLE PATENT DRUG NEBANOL® AGAINST ARTIFICIALLY INDUCED WOUND IN GUINEA PIGS

COMPERATIVE EFFICACY OF THREE INDIGENOUS MEDICINAL PLANTS (TURMERIC, GARLIC, AND ALOE) WITH LOCALLY AVAILABLE PATENT DRUG NEBANOL® AGAINST ARTIFICIALLY INDUCED WOUND IN GUINEA PIGS

... The comparative efficacy of three indigenous medicinal plants i.e. turmeric, garlic, aloe and locally available patent drug Nebanol against artificially induced wound have been examined in twenty-five guinea pigs. ...

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A study of Laparotomy Wound Closure with Skin Staples

A study of Laparotomy Wound Closure with Skin Staples

... WITH SKIN STAPLES” is a bonafide and genuine research work carried out by me in the Department of General Surgery, Madurai Medical College, during the period of September 2013 to August 2014, under the guidance ...

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Effectiveness of interventions for optimising adherence to treatments for the prevention and management of scars: protocol for a systematic review and meta-analysis

Effectiveness of interventions for optimising adherence to treatments for the prevention and management of scars: protocol for a systematic review and meta-analysis

... following wounds of the skin can be complex and time consuming, and patients may experience difficulties adhering to these ...reducing skin scars in adults and children and to determine the ...

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Protein nanocoatings on synthetic polymeric nanofibrous membranes designed as carriers for skin cells

Protein nanocoatings on synthetic polymeric nanofibrous membranes designed as carriers for skin cells

... Advanced skin substitutes should mimic the morphology, composition, and functions of the original ...used skin substitutes have not yet met all these requirements, and they have several limiting ...for ...

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Deregulation of the pRb-E2F4 axis alters epidermal homeostasis and favors tumor development

Deregulation of the pRb-E2F4 axis alters epidermal homeostasis and favors tumor development

... mice regarding hair loss and aberrant anagen entry. Lgr6 is a bona fide epidermal stem cell marker [36] particularly involved in wound repair as well as in the formation of new hair follicles [37]. Importantly, the ...

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Current and future applications of nanotechnology in plastic and reconstructive surgery

Current and future applications of nanotechnology in plastic and reconstructive surgery

... nonhealing wounds (foot, pressure, and venous stasis ulcers, and miscellaneous wounds) were treated with a nanocrystalline sliver dressing [Figure ...those wounds treated with nanocrystalline ...

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