SLE/lupus
Systemic Lupus Erythematosus (SLE)
... for lupus patients depending on severity and activity such that the rheumatologist may have different treatments over the patient's lifetime that need to be ...control lupus over the lifetime helping ...
7
Systemic Lupus Erythematosus (SLE) with Lupus Nephritis in a 15 Year-Old Male – A Case Report
... a lupus diagnosis. Lupus is known as the 'great imitator' because its symptoms mimic many other ...illness. Lupus symptoms can also be unclear, can come and go, and can ...with SLE surveyed ...
6
Susceptibility of BAFF-var allele carriers to severe SLE with occurrence of lupus nephritis
... of SLE has evolved from conventional drugs providing a general immunosuppres- sive function to novel biological-targeting strategies, of which belimumab is an important and successful thera- peutic agent [7, ...
10
Pathogenese des systemischen Lupus erythematodes (SLE) im Kindesalter
... Systemic lupus erythematosus (SLE) is a sys- temic autoimmune disorder that can affect any organ of the human ...pediatric SLE has been ...of SLE in the various age ...
6
A study of cutaneous manifestations in systemic lupus erythematosus
... with SLE and is the strongest overall predictor of morbidity and mortality 34 ...active SLE and the presence of renal ...in SLE are more likely to be localized to one part of the ...C3. Lupus ...
129
Polymorphisms of Toll-like receptor-4 and CD14 in systemic lupus erythematosus and rheumatoid arthritis
... of lupus-like syndrome, increasing the production of auto- antibodies and worsening the renal function impairment ...of SLE and ...and lupus severity was markedly ...
6
New onset non infectious pulmonary manifestations among patients with systemic lupus erythematosus in Sweden
... with SLE who together with their matched comparators from the general popu- lation could be followed with minimal ...cident SLE to evaluate pulmonary disease complications in patients with established and ...
6
Tumor necrosis factor α release in peripheral blood mononuclear cells of cutaneous lupus and dermatomyositis patients
... elevated levels of IFNa and IFNb (both type I IFNs) [27,28]. Because pDCs are the main cell type producing IFNa and IFNb, they have been implicated in disease pathogenesis. A higher proportion of pDCs are also pre- sent ...
11
Neuropsychological patterns in systemic lupus erythematosus patients with depression
... All statistical analyses were conducted with the SAS statistical analysis package (version 9.1; SAS Institute Inc., Cary, NC, USA). Data are presented as means ± SDs for continuous var- iables and as numbers of subjects ...
10
Population and family studies of three disease related polymorphic genes in systemic lupus erythematosus
... multiplex SLE families, 41 unrelated lupus patients, and 88 unrelated healthy ...and SLE in these ...sporadic SLE, the study fails to support this association in familial SLE ...in ...
8
Systemic lupus erythematosus and thrombosis
... that SLE patients are un- able to degrade the NETs (neutrophil extra-cellular traps) complex which regulates apoptotic processes [43]; NETs emerge as a possible mediator of vascular damage and an activator of the ...
10
A short overview on systemic drug induced lupus erythematosus
... The mechanisms to how treatment with anti-TNFα induces lupus are not clear but most likely are different from classic DILE, though three hypothesis have been forwarded [49]. First hypothesis is TNF blockers ...
15
Chicken or the Egg: Anorexia Nervosa and Systemic Lupus Erythematosus in Children and Adolescents
... One patient was diagnosed with AN 15 months after being diagnosed with SLE and 12 months after starting prednisone. Her AN symptoms, including body image dissatisfaction, fear of fat, and desire to lose weight, ...
6
Anti C1q antibodies antedate patent active glomerulonephritis in patients with systemic lupus erythematosus
... full-blown lupus nephritis [10,23,27-29,32-36] or before the diagnosis of lupus nephritis ...with lupus nephritis [32]. Among flares of proliferative lupus nephritis, 20% occurred at a time ...
8
Suppression of lupus nephritis and skin lesions in MRL/lpr mice by administration of the topoisomerase I inhibitor irinotecan
... suppress lupus nephritis in NZB/NZW mice [20], a finding that was based on serendipity obtained from cancer research ex- ...and SLE in ...suppressed lupus nephritis and prolonged survival in NZB/NZW ...
11
IL-22 production of effector CD4+ T-cells is altered in SLE patients
... with lupus nephritis or active disease. Notwithstanding, immunosuppressive treatment could have impact on the capacity to produce effector cytokines. In our present study there was no correlation between the ...
10
Management and outcomes of pregnancy with or without lupus nephritis: a systematic review and meta-analysis
... LN as one of the most serious manifestations of SLE apparently increases the risk of both maternal and fetal adverse outcomes. Our data further support the importance of pregnancy planning, pre-conception ...
17
Systemic lupus erythematosus induced by anti tumour necrosis factor alpha therapy: a French national survey
... of lupus syndrome, due to pre-existing lupus syndrome or due to mixed connective tissue disease before introduction of anti-TNF alpha ...'anti-TNF-induced SLE' based on three ACR criteria (Table ...
7
Systemic lupus erythematosus and pulmonary arterial hypertension: links, risks, and management strategies
... or it could be associated with human immunodeficiency virus, schistosomiasis, portal hypertension, and congenital heart disease as well as with connective tissue diseases (CTDs). PAH related to left heart diseases is ...
9
Bullous lesions as a manifestation of systemic lupus erythematosus in two Mexican teenagers
... of SLE with blisters healed within 3 weeks with potent topical ...of SLE with blisters, the patient's condition was well controlled with progressively decreasing doses of predni- sone and ...
6